Aromatase inhibitors and bipolar mood disorder: a case report

2006 ◽  
Vol 8 (5p1) ◽  
pp. 516-518 ◽  
Author(s):  
Guy M. Goodwin
Keyword(s):  
Case Report ◽  
Mood Disorder ◽  
Aromatase Inhibitors ◽  
Bipolar Mood Disorder

scholarly journals A Case Report: Clozapine in Diabetic Patient with Bipolar Mood Disorder

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
_ Vera ◽  
Christine Sitha
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Case Report ◽  
Weight Gain ◽  
Blood Glucose ◽  
Mood Disorder ◽  
Diabetic Woman ◽  
Diabetic Patients ◽  
Metabolic Abnormalities ◽  
Bipolar Mood Disorder

Depression and diabetes are often occur together and their morbidity has a significant impact of health outcomes. Antidepressants dan antipsychotics may cause metabolic abnormalities, as well as neurologic abnormalities. 52 years old diabetic woman presented to Immanuel Teaching Hospital with slurred speech. Since ten years ago, she had bipolar  mood  disorder, which was recently treated with clozapine. As patient consumed higher dose of clozapine (beyond her psychiatrist’s supervision), she had uncontrolled blood glucose level, fever, and slurred speech. The side effects of clozapine (weight gain, increased insulin resistance, dysarthria, fever) were discussed in this case report. During hospitalization, with strict supervision of clozapine use, the symptoms resolved. In diabetic patients with comorbid psychiatric disorders, a good collaboration between internist and psychiatrist is required to manage the patients effectively and comprehensively. Keywords: bipolar mood disorder, clozapine, diabetes mellitus, depression

scholarly journals Kleptomania, mood disorder and lithium

1992 ◽  
Vol 50 (4) ◽  
pp. 543-546 ◽  
Author(s):  
Fábio Lopes Rocha ◽  
Maria Elizabete Guimarães Rocha
Keyword(s):  
Major Depression ◽  
Mood Disorder ◽  
Mood Disorders ◽  
Pharmacological Treatment ◽  
Lithium Therapy ◽  
Bipolar Mood Disorder

Kleptomania has been found in association with major depression in a fairly large number of reports in recent years. We describe a patient with concurrent DSM-III-R Bipolar Mood Disorder and Kleptomania, whose symptoms remitted completely, apparently in response to lithium therapy, which raised the possibility that pharmacological treatment may benefit kleptomania. Further studies are needed to establish the possible relationship between kleptomania, mood disorders and lithium therapy.

scholarly journals Subepithelial Corneal Deposits Associated with Exemestane

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Annahita Amireskandari ◽  
Elena Nguyen ◽  
David Hinkle ◽  
Thomas Mauger
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Aromatase Inhibitors ◽  
Initial Visit ◽  
Slight Improvement ◽  
Number Of Patients ◽  
Corneal Deposits ◽  
Eye Clinic ◽  
New Onset

This is a case report of corneal deposits noted in a 69-year-old female patient taking the aromatase inhibitor, exemestane, after undergoing a mastectomy and chemotherapy for breast cancer. The patient presented to our eye clinic for a new-onset floater in one eye, and bilateral subepithelial opacities were found incidentally on exam. The patient completed a 5-year course of the medication shortly after her initial visit with us and was noted to have a slight improvement in the density of the opacities on a follow-up visit 3 months later. We believe these corneal changes were most likely secondary to exemestane. The effect of aromatase inhibitors on the eye deserves further exploration as an increasing number of patients are prescribed these medications.

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