Genetic polymorphisms of CD14 and Toll-like receptor-2 (TLR2) in patients with ulcerative colitis

2007 ◽  
Vol 22 (6) ◽  
pp. 925-929 ◽  
Author(s):  
Fangyu Wang ◽  
Tomomitsu Tahara ◽  
Tomiyasu Arisawa ◽  
Tomoyuki Shibata ◽  
Masakatsu Nakamura ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Genetic Polymorphisms ◽  
Toll Like Receptor ◽  
Toll Like Receptor 2

Genetic polymorphisms of CD14, Toll-like receptor-2 and Manan-binding lectin in ulcerative colitis

2007 ◽  
Vol 13 ◽  
pp. 653-654
Author(s):  
T Tahara ◽  
T Arisawa ◽  
F Wang ◽  
T Shibata ◽  
M Nakamura ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Genetic Polymorphisms ◽  
Toll Like Receptor ◽  
Toll Like Receptor 2 ◽  
Binding Lectin

Genetic polymorphisms of CD14, Toll-like receptor-2 and Manan-binding lectin in ulcerative colitis

2007 ◽  
Vol 13 (supplement) ◽  
pp. 653-654
Author(s):  
T Tahara ◽  
T Arisawa ◽  
F Wang ◽  
T Shibata ◽  
M Nakamura ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Genetic Polymorphisms ◽  
Toll Like Receptor ◽  
Toll Like Receptor 2 ◽  
Binding Lectin

Toll-like receptor 2 and 9 genetic polymorphisms and the susceptibility to B cell Non-Hodgkin Lymphoma in Egypt

2014 ◽  
Vol 93 (11) ◽  
pp. 1859-1865 ◽  
Author(s):  
Hala Aly Abdel Rahman ◽  
Mervat Mamdooh Khorshied ◽  
Ola M. Reda Khorshid ◽  
Shirihan Mahmoud Mahgoub
Keyword(s):  
B Cell ◽  
Hodgkin Lymphoma ◽  
Genetic Polymorphisms ◽  
Toll Like Receptor ◽  
Non Hodgkin Lymphoma ◽  
Toll Like Receptor 2

scholarly journals Expression of Toll-like Receptor 2 (TLR2), TLR4, and CD14 in Biopsy Samples of Patients With Inflammatory Bowel Diseases: Upregulated Expression of TLR2 in Terminal Ileum of Patients With Ulcerative Colitis

2007 ◽  
Vol 56 (3) ◽  
pp. 267-274 ◽  
Author(s):  
Lenka Frolova ◽  
Pavel Drastich ◽  
Pavel Rossmann ◽  
Klara Klimesova ◽  
Helena Tlaskalova-Hogenova
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Diseases ◽  
Terminal Ileum ◽  
Immunohistochemical Analysis ◽  
Toll Like Receptor ◽  
Tlr2 Expression ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Toll Like Receptor 2 ◽  
Active Disease

Dysregulation of innate and adaptive intestinal immune responses to bacterial microbiota is supposed to be involved in pathogenetic mechanisms of inflammatory bowel diseases (IBDs). We investigated expression of Toll-like receptor 2 (TLR2), TLR4, and their transmembrane coreceptor CD14 inbiopsy samples from patients with IBD and in non-inflamed gut mucosa from controls. Small intestine and colon samples were obtained by colonoscopy from patients with Crohn's disease (CD), ulcerative colitis (UC), and controls. Immunohistochemical analysis of cryostat sections using polyclonal and monoclonal antibodies specific for TLR2, TLR4, and CD14 showed a significant increase in TLR2 expression in the terminal ileum of patients with inactive and active UC against controls. Significant upregulation of TLR4 expression relative to controls was found in the terminal ileum and rectum of UC patients in remission and in the terminal ileum of CD patients with active disease. CD14 expression was upregulated in the terminal ileum of CD patients in remission and with active disease, in the cecum of UC patients in remission and with active disease, and in rectum of UC patients with active disease. Hence, dysregulation of TLR2, TLR4, and CD14 expression in different parts of the intestinal mucosa may be crucial in IBD pathogenesis.

Association between genetic polymorphisms of Toll-like receptor 2 (TLR2) and schizophrenia in the Korean population

Gene ◽  
2013 ◽  
Vol 526 (2) ◽  
pp. 182-186 ◽  
Author(s):  
Won Sub Kang ◽  
Jin Kyung Park ◽  
Sang Min Lee ◽  
Su Kang Kim ◽  
Hae Jeong Park ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Korean Population ◽  
Toll Like Receptor ◽  
Toll Like Receptor 2

Toll-like receptor 2 signaling is important for fas ligand on NKT cells, may contribute to liver injury induced by Salmonella infection

2001 ◽  
Vol 120 (5) ◽  
pp. A357-A357
Author(s):  
H SHIMIZU ◽  
Y FUKUDA ◽  
I NAKANO ◽  
Y KATANO ◽  
K NAGANO ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fas Ligand ◽  
Nkt Cells ◽  
Toll Like Receptor ◽  
Salmonella Infection ◽  
Toll Like Receptor 2
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