Hepatitis B virus genotypes and hepatitis B surface antigen mutations in family contacts of hepatitis B virus infected patients with occult hepatitis B virus infection

2009 ◽  
Vol 24 (4) ◽  
pp. 588-598 ◽  
Author(s):  
Gollapudi Tarun Kumar ◽  
Syed Naqui Kazim ◽  
Manoj Kumar ◽  
Syed Hissar ◽  
Ranjit Chauhan ◽  
...  
2008 ◽  
Vol 80 (8) ◽  
pp. 1344-1349 ◽  
Author(s):  
H.L. Zaaijer ◽  
P. Torres ◽  
A. Ontañón ◽  
L. González Ponte ◽  
M.H.G.M. Koppelman ◽  
...  

2007 ◽  
Vol 79 (3) ◽  
pp. 220-228 ◽  
Author(s):  
Sonali Sengupta ◽  
Shagufta Rehman ◽  
Hemlata Durgapal ◽  
Subrat Kumar Acharya ◽  
Subrat Kumar Panda

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Oluyinka Oladele Opaleye ◽  
Adeolu Sunday Oluremi ◽  
Adetona Babatunde Atiba ◽  
Moses Olubusuyi Adewumi ◽  
Olatunji Victor Mabayoje ◽  
...  

HIV has been known to interfere with the natural history of hepatitis B virus (HBV) infection. In this study we investigate the prevalence of occult hepatitis B virus infection (OBI) among HIV-infected individuals in Nigeria. Overall, 1200 archived HIV positive samples were screened for detectable HBsAg using rapid technique, in Ikole Ekiti Specialist Hospital. The HBsAg negative samples were tested for HBsAg, anti-HBc, and anti-HCV by ELISA. Polymerase chain reaction was used for HBV DNA amplification and CD4 counts were analyzed by cytometry. Nine hundred and eighty of the HIV samples were HBsAg negative. HBV DNA was detected in 21/188 (11.2%) of patients without detectable HBsAg. CD4 count for the patients ranged from 2 to 2,140 cells/μL of blood (mean = 490 cells/μL of blood). HCV coinfection was detected only in 3/188 (1.6%) of the HIV-infected patients (P>0.05). Twenty-eight (29.2%) of the 96 HIV samples screened were positive for anti-HBc. Averagely the HBV viral load was <50 copies/mL in the OBI samples examined by quantitative PCR. The prevalence of OBI was significantly high among HIV-infected patients. These findings highlight the significance of nucleic acid testing in HBV diagnosis in HIV patients.


2014 ◽  
Vol 165 (4) ◽  
pp. 773-778 ◽  
Author(s):  
Steven L. Veselsky ◽  
Tanja Y. Walker ◽  
Nancy Fenlon ◽  
Chong-Gee Teo ◽  
Trudy V. Murphy

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