MALIGNANT FIBROUS HISTIOCYTOMA WITH GRANULAR CELLS, MIMICKING A GRANULAR CELL TUMOR: Light, Electron Microscopic and Immunohistochemical Observation of a Case

1985 ◽  
Vol 35 (6) ◽  
pp. 1555-1560
Author(s):  
Akira Tanimura ◽  
Kazuhiko Nagayama ◽  
Yasuhiro Nakamura ◽  
Syunichi Tanaka ◽  
Tatsuo Tanaka
Keyword(s):  
Malignant Fibrous Histiocytoma ◽  
Granular Cell Tumor ◽  
Fibrous Histiocytoma ◽  
Granular Cell ◽  
Cell Tumor ◽  
Granular Cells ◽  
Electron Microscopic

Multifocal Granular Cell Tumor of the Esophagus and Proximal Stomach With Infiltrative Pattern

1999 ◽  
Vol 123 (10) ◽  
pp. 967-973 ◽  
Author(s):  
Odile David ◽  
Shriram Jakate
Keyword(s):  
Gastrointestinal Tract ◽  
Granular Cell Tumor ◽  
African American Woman ◽  
American Woman ◽  
Granular Cell ◽  
Cell Tumor ◽  
Granular Cells ◽  
Review Of The Literature ◽  
Proximal Stomach

Abstract The granular cell tumor is a solitary painless nodule that arises most commonly on the skin or the tongue. The vast majority are benign. Approximately 5% to 9% of granular cell tumors have been reported in the gastrointestinal tract, most commonly in the esophagus. We report a case of a 45-year-old African American woman with multifocal granular cell tumors of the esophagus and proximal stomach. Two lesions within the distal esophagus and proximal stomach were characteristic nodular granular cell tumors. Within the mid esophagus there was poorly defined transmural involvement by benign-appearing granular cells. This pattern of infiltration by benign cells is uncharacteristic. A review of the literature with emphasis on the determination of malignancy is also presented.

Giant Granular Cell Tumor of the Suprasellar Area; Immunocytochemical and Electron Microscopic Studies

Neurosurgery ◽  
1984 ◽  
Vol 15 (2) ◽  
pp. 246-251 ◽  
Author(s):  
Boleslaw H. Liwnicz ◽  
Boleslaw H. Liwnicz ◽  
Regina G. Liwnicz ◽  
Stephen J. Huff ◽  
Bert H. McBride ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Granular Cell Tumor ◽  
Periodic Acid ◽  
Granular Cell ◽  
Cell Tumor ◽  
Electron Microscopic ◽  
Periodic Acid Schiff ◽  
Computed Tomographic ◽  
Suprasellar Region ◽  
Microscopic Studies

Abstract We describe a case of a granular cell tumor (GCT) of the suprasellar region with an 11-year history in a 26-year-old woman. The computed tomographic scan showed a midline, contrast-enhancing, noncalcified mass. The biopsy was diagnosed as GCT. The tumor was treated with radiation therapy. At necropsy, a large, homogeneous GCT surrounded by gliosis was found. The tumor cells were filled with granules positive for periodic acid-Schiff, diastase-resistant. The cells did not contain glial fibrillary acidic protein or S-100 protein. Electron microscopy showed tumor cells filled with innumerable lysosomal structures. No intermediate filament was found within the cytoplasm. The tumor cells were not surrounded by a basement membrane. Based on this study and on our review of the literature, the suggestion that GCT has a multicellular origin is upheld.

Granular Cell Variants in a Rat Schwannoma. Evidence of Neurogenic Origin of Granular Cell Tumor (Myoblastoma)

1978 ◽  
Vol 15 (6) ◽  
pp. 725-731 ◽  
Author(s):  
J. J. Berman ◽  
J. M. Rice ◽  
J. Strandberg
Keyword(s):  
Schwann Cells ◽  
Granular Cell Tumor ◽  
Periodic Acid ◽  
Granular Cell ◽  
Cell Tumor ◽  
Granular Cells ◽  
Periodic Acid Schiff ◽  
Pas Reaction ◽  
Granular Cytoplasm ◽  
General Configuration

A large, intraabdominal rat schwannoma had numerous granule-containing cells cytologically identical to cells of granular cell tumor (myoblastoma). The small eosinophilic granules stained positively by the periodic acid-Schiff (PAS) reaction, with intensity not reduced by diastase pretreatment. Granules stained positively with the Tibor Pap silver impregnation for reticulin and by electron microscopy were identical to myoblastoma cell granules. The nuclei of granular cells were morphologically identical to those of the neoplastic Schwann cells. The granular cells were in numerous foci within the tumor, frequently were seen in mitosis, and possessed an extremely variable volume of cytoplasm. They seemed to evolve from neoplastic Schwann cells. Cells with only a narrow perinuclear rim of granular cytoplasm were of the same size and general configuration as adjacent neoplastic Schwann cells, while cells with increasing volumes of granular cytoplasm were increasingly swollen and round. One area of the tumor was composed almost entirely of such large cells and was histologically identical to classic granular cell tumor.

Granular cell tumor of the pituitary stalk

1994 ◽  
Vol 80 (6) ◽  
pp. 1103-1107 ◽  
Author(s):  
Catherine Lafitte ◽  
Bruno Aesch ◽  
Françoise Henry-Lebras ◽  
Franck Fetissof ◽  
Michel Jan
Keyword(s):  
Granular Cell Tumor ◽  
Histopathological Examination ◽  
Granular Cell ◽  
Brain Parenchyma ◽  
Magnetic Resonance Images ◽  
Cell Tumor ◽  
Pituitary Stalk ◽  
Electron Microscopic ◽  
Content Type ◽  
Microscopic Studies

✓ The case is described of a granular cell tumor of the pituitary stalk in a 40-year-old woman with secondary amenorrhea. A computerized tomography scan showed a large contrast-enhancing mass, and T1-weighted magnetic resonance images demonstrated a tumor isointense to the brain parenchyma with nonhomogeneous enhancement after intravenous administration of gadolinium diethylenetriamine penta-acetic acid. Histopathological examination, especially immunocytochemical and electron microscopic studies, showed elements supporting an astrocytic origin for this type of tumor, a hypothesis advanced by many authors but still controversial.

Abstract #804: Granular Cell Tumor of the Neurohypophysis

2017 ◽  
Vol 23 ◽  
pp. 163
Author(s):  
Dalitza Alvarez-Valentin ◽  
Milliette Alvarado Santiago ◽  
Loida Gonzalez-Rodriguez ◽  
Margarita Ramirez-Vick ◽  
Juan Perez-Berenguer
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor
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