Urodynamic study alterations in a patient with stiff person syndrome

Abstract Objective To evaluate whether performing preoperative urodynamic study influences postoperative urinary symptoms of women with stress urinary incontinence that underwent transobturator sling. Methods Retrospective analysis of patients treated for stress urinary incontinence by transobturator sling from August 2011 to October 2018. Predictor variables included preoperative urodynamic study, age, incontinence severity, body mass index, preoperative storage symptoms and previous anti-urinary incontinence procedure. Outcome variables were postoperative subjective continence status, storage symptoms and complications. Logistic regression after propensity score was employed to compare outcomes between patients who underwent or not pre-operative urodynamic study. Results The present study included 88 patients with an average follow-up of 269 days. Most patients (n = 52; 59.1%) described storage symptoms other than stress urinary incontinence, and 38 patients (43.2%) underwent preoperative urodynamic studies. Logistic regression after propensity score did not reveal an association between urinary continence outcomes and performance of preoperative urodynamic study (odds ratio 0.57; confidence interval [CI]: 0.11–2.49). Among women that did not undergo urodynamic study, there was a subjective improvement in urinary incontinence in 92% of the cases versus 87% in those that underwent urodynamic study (p = 0.461). Furthermore, postoperative storage symptoms were similar between women who did not undergo urodynamic study and those who underwent urodynamic study, 13.2% versus 18.4%, respectively (p = 0.753). Conclusion Preoperative urodynamic study had no impact on urinary incontinence cure outcomes as well as on urinary storage symptoms after the transobturator sling in women with stress urinary incontinence.

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Respective implications of glutamate decarboxylase antibodies in stiff person syndrome and cerebellar ataxia

Orphanet Journal of Rare Diseases ◽

10.1186/1750-1172-6-3 ◽

2011 ◽

Vol 6 (1) ◽

pp. 3 ◽

Cited By ~ 49

Author(s):

Mario U Manto ◽

Christiane S Hampe ◽

Veronique Rogemond ◽

Jerome Honnorat

Keyword(s):

Cerebellar Ataxia ◽

Glutamate Decarboxylase ◽

Stiff Person Syndrome

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Poster 360 Acute Rehabilitation of a Patient with Stiff Person Syndrome (SPS) and GAD-Antibody Cerebellar Ataxia: A Case Report

PM&R ◽

10.1016/j.pmrj.2016.07.288 ◽

2016 ◽

Vol 8 (9) ◽

pp. S278-S279

Author(s):

Nicole A. Strong ◽

Nicholas F. Love ◽

Kristen M. Brusky ◽

Sara Salim

Keyword(s):

Case Report ◽

Cerebellar Ataxia ◽

Stiff Person Syndrome ◽

Acute Rehabilitation

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Incidence of Bacteriuria after Urodynamic Study with or without Antibiotic Prophylaxis in Women with Urinary Incontinence

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics ◽

10.1055/s-0037-1604066 ◽

2017 ◽

Vol 39 (10) ◽

pp. 534-540 ◽

Cited By ~ 5

Author(s):

Elizabeth Hirakauva ◽

Ana Bianchi-Ferraro ◽

Eliana Zucchi ◽

Marcio Kajikawa ◽

Manoel Girão ◽

...

Keyword(s):

Urinary Incontinence ◽

Placebo Group ◽

Urinary Tract ◽

Antibiotic Prophylaxis ◽

Urine Culture ◽

Placebo Control ◽

Urodynamic Study ◽

Group A ◽

Group B ◽

Group D

Introduction The presence of bacteria in urine is called bacteriuria, which may be symptomatic or asymptomatic. The manipulation of the urinary tract during urodynamic study (UDS), which is an invasive procedure, can result in urinary tract infection (UTI). Studies on the use of prophylactic antibiotics for UDSs are contradictory. Some investigators concluded that they were valuable and others did not. The objective of this study is to evaluate the efficacy of antibiotic prophylaxis before UDS. This is a placebo-control randomized double-blind study. Methods Two-hundred and seventeen women affected by urinary incontinence were eligible for this study. All patients had presented negative urine culture previous to the UDS. They were randomized in four groups: group A received placebo, group B received 500 mg of levofloxacin, group C received 80 mg trimethoprim and 400 mg sulfamethoxazole and group D received 100 mg of nitrofurantoin. A urine culture was performed 14 days after the UDS. Results We observed asymptomatic bacteriuria after the UDS in five patients in group A, one in group B, one in group C and one in group D. Only one patient on group A had symptomatic bacteriuria. We didn't observe statistical difference between the groups. When we recategorized the patients in two groups, the incidence of bacteriuria was significantly higher in the placebo group compared with the antibiotic group. Conclusion The conclusion is that antibiotic prophylaxis before the UDS did not reduce the incidence of UTI in women within the target population.

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