Auditory Event-Related Potentials and Reaction Times in Migraine Children

Cephalalgia ◽  
2004 ◽  
Vol 24 (7) ◽  
pp. 554-563 ◽  
Author(s):  
G Buodo ◽  
D Palomba ◽  
M Sarlo ◽  
C Naccarella ◽  
PA Battistella

Cognitive processing was investigated interictally in 18 children with migraine without aura and 18 age-matched controls by measuring event-related potentials (ERPs) and reaction times (RTs) during an acoustic oddball paradigm. Results showed that N100 amplitude evoked by frequent stimuli was significantly smaller in patients compared with controls. Habituation of target P300 amplitude was observed in patients but not in controls. Mean RTs were equivalent in the two groups, but migraine children made more errors than controls.

2007 ◽  
Vol 18 (02) ◽  
pp. 107-116 ◽  
Author(s):  
Angela C. Garinis ◽  
Barbara K. Cone-Wesson

The effect of stimulus level on cortical auditory event-related potentials (ERPs) evoked by consonant-vowel (CV) contrasts, /ta/, /da/, and /sa/, was investigated. The lowest level at which CVs were discriminated with >95% accuracy was determined for 15 normally hearing adults. ERPs were obtained at 0, 20, and 40 dB SL above this level during active listening. ERP latencies decreased as level increased. P300 amplitude did not vary with CV level or type; however, obligatory ERPs decreased in amplitude as level increased. The effect of level on P300 latency is likely related to the cognitive processing speed needed to perform speech discrimination. Obligatory ERP amplitude results suggest that attention demands vary with level during discrimination of speech features. Se investigó el efecto del nivel del estímulo en potenciales auditivos corticales relacionados con el evento (ERP) evocados por contrastes consonante-vocal (CV), /ta/, /da/ y /sa/. Se determinó en 15 adultos normoyentes el nivel menor al que se discriminaron los CV con > 95% de exactitud. Los ERP fueron obtenidos a 0, 20 y 40 dB SL por encima de este nivel durante audición activa. Las latencias de los ERP disminuyeron conforme los niveles aumentaron. La amplitud de la P300 no varió con el nivel o el tipo de los CV; sin embargo, las amplitudes siempre bajaron conforme subió el nivel. El efecto del nivel sobre las P300 parece estar relacionado con la velocidad de procesamiento cognitivo necesaria para realizar discriminación del lenguaje. Los resultados obligatorios de la amplitud de los ERP sugieren que las demandas de atención varían durante la discriminación de rasgos del lenguaje.


Open Medicine ◽  
2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Hakan Tekeli ◽  
Hasan Koçoğlu ◽  
Cabir Alan ◽  
Mustafa Emir Tavşanlı ◽  
Halit Yaşar ◽  
...  

AbstractBackground: Hypospadias is a common urogenital system disorder. The frenulum, which is the most sensitive area of the glans penis, is not present in patients with hypospadias. This may lead to a failure in sexual and ejaculatory function, and cause emotional problems affecting cognitive processes.Aim: We aimed to study auditory Event Related Potentials (ERP) in patients with hypospadias to understand the status of cognitive function.Materials and Methods: Seventeen patients with hypospadias who presented to the Urology Outpatient Clinic of Çanakkale Military Hospital, and 11 healthy individuals of similar age were chosen. The auditory oddball paradigm with ERP from the Cz and Fz head regions were studied. The latency and amplitude of the P300 wave were measured.Results: Both, the study and control groups consisted of young males. Although the study group had a longer P300 latency and lower P300 amplitude when compared to control group, the results were not statistically significant (p: 0.059 and 0.346 respectively).Conclusion: Although the results are not statistically significant, our findings indicate that there may be cognitive changes in patients with hypospadias. Further studies of larger sample size and older patient cohorts are needed.


1991 ◽  
Vol 1 (1) ◽  
pp. 48-55 ◽  
Author(s):  
Dana L. Oviatt ◽  
Paul R. Kileny

Auditory event-related evoked potentials (ERP) were recorded from 10 cochlear implant recipients and 10 age-matched hearing subjects using an oddball paradigm in which frequently occurring tone bursts of 500 Hz were interspersed within rarely occurring tone bursts of 1000, 2000, or 3000 Hz. Signals were delivered acoustically to both groups of subjects through a loudspeaker. P-300 peak latencies for the implant recipients were significantly longer than those for the hearing subjects for the 500–1000 and 500–2000 Hz frequency contrast conditions, but not for the 500–3000 Hz contrast condition. For the hearing subjects, P3 latency did not change significantly across the three frequency contrast conditions; however, for the implant recipients, P3 latencies were significantly longer for the 500–1000 Hz signal contrasts than for 500–2000 and 500–3000 Hz signal contrasts. These results suggest that although implant recipients had more difficulty than hearing subjects in discriminating the 500–1000 and 500–2000 Hz contrasts, the implant recipients and hearing subjects discriminated the widest 500–3000 Hz frequency contrast equally well. The ERP appears to be a reliable index of signal detection and discrimination in cochlear implant recipients and consequently may be useful for device programming and for monitoring the progress of these individuals.


2020 ◽  
Vol 16 (4) ◽  
pp. 314-320
Author(s):  
Jinsook Kim ◽  
Kieun Lee ◽  
Eunsung Lee

Purpose: This study was to determine the effects of response tasks, such as button pressing and mental counting, and handedness on N100, N200, and P300 auditory event-related potential (AERP).Methods: A total of 50 normal-hearing young adults with the average age of 21.6 (±1.5) years participated in this study. Among them, 15 men and 15 women were right-handed and 10 men and 10 women were left-handed. An oddball paradigm was used to deliver 30 stimuli of 2 kHz target tone bursts and 120 stimuli of 1 kHz nontarget tone bursts. The stimuli were presented at 70 dB sound pressure level with the rate of 1/s.Results: The button pressing task elicited significantly smaller N100 and larger P300 amplitudes than the mental counting task. N200 latency was significantly lower and P300 amplitude was higher in left-handed participants than those who are right-handed. Appearance percentages of right-/left-handed participants for N100, N200, and P300 were 80/95%, 85/85%, and 75/75% for the button pressing task and 80/90%, 80/80%, and 70/70% for mental counting task, respectively.Conclusion: The significant difference in appearance percentage between response tasks supported that P300 was a strong endogenous potential. N100 and N200 were thought to have both endogenous and exogenous characteristics. A more sensitive approach in selecting the task of response for the target stimuli and careful consideration for the handedness is necessary for AERP recordings.


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