Malignant melanoma of the vulva: clinicopathological features

1991 ◽  
Vol 1 (2) ◽  
pp. 81-87 ◽  
Author(s):  
K. Blessing ◽  
N. M. Kernohan ◽  
I. D. Miller ◽  
A. I. Al Nafussi
Keyword(s):  
Lymph Node ◽  
Surgical Treatment ◽  
Survival Rate ◽  
Malignant Melanoma ◽  
Palliative Treatment ◽  
Elderly Women ◽  
Clinicopathological Features ◽  
Node Dissection ◽  
The Mean ◽  
Radical Vulvectomy

From the files of the Scottish Melanoma Group, we have identified 41 cases of vulval malignant melanoma, which represents 1.7% of all the melanomas occurring in women in Scotland, during the period 1979–1989. Thirty-seven were aged 50 years or older with the mean age being 70 years. The average Breslow depth of the lesions was 6.0 mm, with 29 being greater than 3.0 mm in depth. Nineteen cases were polypoidal and 37 were ulcerated. Six patients had radical vulvectomy with lymph node dissection, three had biopsy and palliative treatment, and the majority of the remaining patients had local excision only, with surgical margins of less than 2 cm. The 5-year survival rate (available for 23 patients) is 21.7%, compared to 72% for cutaneous melanoma in females, in general, in the same population. In this series, the survival rate is poor, as the lesions occurred in elderly women and the melanomas were thick at presentation. Surgical treatment appears to have been rather conservative in those who were dead from their disease at 5 years.

scholarly journals Paratesticular Tumors in the Service of Urology Ibn Rochd UHC: Epidemioclinical and Therapeutic Aspects

2020 ◽  
Vol 2 (5) ◽  
Author(s):  
W. Bai ◽  
M. Graiouid ◽  
G. Hatim ◽  
A. Doumer ◽  
M. Dakir ◽  
...  
Keyword(s):  
Lymph Node ◽  
Retrospective Study ◽  
Surgical Treatment ◽  
Lymph Node Dissection ◽  
Clinical Presentation ◽  
Age Of Onset ◽  
Urogenital System ◽  
Node Dissection ◽  
Scrotal Mass ◽  
The Mean

Objective: To analyze the frequency, clinical and therapeutic aspects of paratesticular tumors in the urology department of the Ibn Rochd UHC. Patients and methods: Retrospective study of 5 patients with partesticular tumors treated in the urology department of Ibn Rochd UHC between January 2014 and December 2019. The parameters studied were age, circumstances of discovery, histological type of the tumor and the treatment performed. Results: Five paratesticular tumors were recorded among all patients admitted for a tumor of the urogenital system, representing a prevalence of 0.52%. The mean age of onset was 27 years (range 17—65 years). The circumstances of discovery were a scrotal mass in 60% of the cases, that is to say three patients and an inguinoscrotal mass in two patients. Several histological types of tumors have been recorded: three cases of rhabdomyosarcomas, either 60%, one case of sarcoma, either 20%, and one case of fibroma. The modalities of the surgical treatment carried out were enlarged orchidectomy by upper inguinal approach with lymph node dissection in two patients, enlarged orchidectomy by upper inguinal approach without lymph node dissection in two cases and one case of tumerectomy. Conclusion: Paratesticular tumors are rare. They are found mainly in young adults. The clinical presentation is variable and the diagnosis often late. Management is multidisciplinary but remains essentially surgical. Our study illustrates the great histopathological variability of paratesticular tumors. 

scholarly journals Infectious Morbidity After Radical Vulvectomy

1994 ◽  
Vol 2 (3) ◽  
pp. 130-135 ◽  
Author(s):  
Steven A. Elg ◽  
Linda F. Carson ◽  
Doris C. Brooker ◽  
Jonathan R. Carter ◽  
Leo B. Twiggs
Keyword(s):  
Lymph Node ◽  
Lymph Node Dissection ◽  
Postoperative Infection ◽  
Inguinal Lymph Node ◽  
Tumor Stage ◽  
Cancer Type ◽  
Node Dissection ◽  
Inguinal Lymph Node Dissection ◽  
Infectious Morbidity ◽  
Radical Vulvectomy

Objective: This retrospective investigation describes the infectious morbidity of patients following radical vulvectomy with or without inguinal lymph node dissection.Methods: The charts of patients undergoing radical vulvectomy between January 1, 1986, and September 1, 1989, were reviewed for age, weight, cancer type, tumor stage, operative procedure(s), prophylactic antibiotic and its length of use, febrile morbidity, infection site, culture results, significant medical history, and length of use and number of drains or catheters used.Results: The study group was composed of 61 patients, 14 of whom underwent a radical vulvectomy and 47 who also had inguinal lymph node dissection performed. Twenty-nine patients (48%) had at least 1 postoperative infection. Five patients (8%) had 2 or more postoperative infections. The site and incidence of the infections were as follows: urinary tract 23%, wound 23%, lymphocyst 3%, lymphatics (lymphangitis) 5%, and bowel (pseudomembranous colitis) 3%. The most common pathogens isolated from both urine and wound sites were Pseudomonas aeruginosa, enterococcus, and Escherichia coli. A significant decrease in wound infection was demonstrated when separate incisions were made for inguinal lymph node dissection (P <0.05). The mean number of days to onset of postoperative infection for wound, urine, lymphatics, lymphocyst, and bowel were 11, 8, 57, 48, and 5, respectively.Conclusions: We conclude that the clinical appearance of post-radical vulvectomy infections is delayed when compared with other post-surgical wound infections. Second, utilizing separate inguinal surgical incisions may reduce infectious morbidity. Finally, tumor stage and type do not necessarily increase the infectious morbidity of radical vulvar surgery.

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