GABAAReceptor Subtype-Selective Efficacy: TPA023, an α2/α3 Selective Non-sedating Anxiolytic and α5IA, an α5 Selective Cognition Enhancer

John R. Atack

doi:10.1111/j.1527-3458.2007.00034.x

GABAAReceptor Subtype-Selective Efficacy: TPA023, an α2/α3 Selective Non-sedating Anxiolytic and α5IA, an α5 Selective Cognition Enhancer

CNS Drug Reviews ◽

10.1111/j.1527-3458.2007.00034.x ◽

2008 ◽

Vol 14 (1) ◽

pp. 25-35 ◽

Cited By ~ 3

Author(s):

John R. Atack

Keyword(s):

Subtype Selective

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Induction of β-defensin expression in Crohn's disease: Activity relate expression profile and subtype selective upregulation in gastrointestinal tissues

Gastroenterology ◽

10.1016/s0016-5085(01)81588-2 ◽

2001 ◽

Vol 120 (5) ◽

pp. A320-A320

Author(s):

A DEWEERTH ◽

M BLAEKER ◽

A REISSER ◽

M SCHULZ

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Disease Activity ◽

Expression Profile ◽

Crohn’S Disease Activity ◽

Subtype Selective

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GABA(A) receptor subtype-selective loreclezole analogues targeting an α6-specific site

Intrinsic Activity ◽

10.25006/ia.7.s1-a3.12 ◽

2019 ◽

Vol 7 (Suppl. 1) ◽

pp. A3.12

Author(s):

Doris Enz

Keyword(s):

Specific Site ◽

Receptor Subtype ◽

Gaba A ◽

Subtype Selective

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Faculty Opinions recommendation of Reversal of a vigilance decrement in the aged rat by subtype-selective nicotinic ligands.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1013858.191524 ◽

2003 ◽

Author(s):

Trevor W Robbins

Keyword(s):

Vigilance Decrement ◽

Aged Rat ◽

Subtype Selective

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Faculty Opinions recommendation of Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1064759.517678 ◽

2007 ◽

Author(s):

Hugh Rosen

Keyword(s):

Biological Evaluation ◽

Receptor Agonists ◽

Sphingosine 1 Phosphate ◽

Subtype Selective ◽

Synthesis And Biological Evaluation ◽

Receptor Agonists And Antagonists

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Subtype-selective desensitization of alpha 2-adrenergic receptors. Different mechanisms control short and long term agonist-promoted desensitization of alpha 2C10, alpha 2C4, and alpha 2C2.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)74065-4 ◽

1992 ◽

Vol 267 (35) ◽

pp. 25473-25479

Author(s):

M.G. Eason ◽

S.B. Liggett

Keyword(s):

Adrenergic Receptors ◽

Short And Long Term ◽

Subtype Selective

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Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

PLoS ONE ◽

10.1371/journal.pone.0152405 ◽

2016 ◽

Vol 11 (4) ◽

pp. e0152405 ◽

Cited By ~ 84

Author(s):

Aristos J. Alexandrou ◽

Adam R. Brown ◽

Mark L. Chapman ◽

Mark Estacion ◽

Jamie Turner ◽

...

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Axonal Conduction ◽

Presynaptic Release ◽

Subtype Selective

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A Bipartite Recombinant Yeast System for the Identification of Subtype-Selective Estrogen Receptor Ligands

Molecular Biotechnology ◽

10.1007/s12033-008-9141-9 ◽

2009 ◽

Vol 41 (3) ◽

pp. 307-307

Author(s):

Kaiwei Liang ◽

Liuqing Yang ◽

Zhimin Xiao ◽

Jian Huang

Keyword(s):

Estrogen Receptor ◽

Recombinant Yeast ◽

Receptor Ligands ◽

Estrogen Receptor Ligands ◽

Subtype Selective

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SKF-82958 Is a Subtype-selective Estrogen Receptor-α (ERα) Agonist That Induces Functional Interactions between ERα and AP-1

Journal of Biological Chemistry ◽

10.1074/jbc.m109320200 ◽

2001 ◽

Vol 277 (3) ◽

pp. 1669-1679 ◽

Cited By ~ 17

Author(s):

Marian R. Walters ◽

Martin Dutertre ◽

Carolyn L. Smith

Keyword(s):

Estrogen Receptor ◽

Estrogen Receptor Α ◽

Functional Interactions ◽

Skf 82958 ◽

Subtype Selective

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A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit

Journal of Biological Chemistry ◽

10.1074/jbc.m115.676551 ◽

2015 ◽

Vol 290 (48) ◽

pp. 28834-28846 ◽

Cited By ~ 11

Author(s):

Jingyi Wang ◽

Alexander Kuryatov ◽

Zhuang Jin ◽

Jack Norleans ◽

Theodore M. Kamenecka ◽

...

Keyword(s):

Nicotinic Acetylcholine Receptors ◽

Acetylcholine Receptors ◽

Allosteric Modulator ◽

Positive Allosteric Modulator ◽

Nicotinic Acetylcholine ◽

Α Subunit ◽

Subtype Selective

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Subtype-selective conopeptides targeted to nicotinic receptors:Concerted discovery and biomedical applications

Channels ◽

10.4161/chan.2.2.6276 ◽

2008 ◽

Vol 2 (2) ◽

pp. 143-152 ◽

Cited By ~ 49

Author(s):

Baldomero M Olivera ◽

Maryka Quik ◽

Michelle Vincler ◽

J. Michael McIntosh

Keyword(s):

Biomedical Applications ◽

Subtype Selective

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