The impact of beta-blocker therapy on anemia after traumatic brain injury

Transfusion ◽  
2012 ◽  
Vol 52 (10) ◽  
pp. 2155-2160 ◽  
Author(s):  
Nina E. Glass ◽  
Lisa A. Kaltenbach ◽  
Sloan B. Fleming ◽  
Patrick G. Arbogast ◽  
Bryan A. Cotton
2009 ◽  
Vol 151 (2) ◽  
pp. 300
Author(s):  
B.A. Cotton ◽  
N.E. Glass ◽  
L.A. Kaltenbach ◽  
P. Arbogast

2008 ◽  
Vol 25 (4) ◽  
pp. E8 ◽  
Author(s):  
Timothy Y. Tran ◽  
Irie E. Dunne ◽  
John W. German

Traumatic brain injury (TBI) continues to carry a significant public health burden and is anticipated to worsen worldwide over the next century. Recently the authors of several articles have suggested that exposure to beta blockers may improve mortality rates following TBI. The exact mechanism through which beta blockers mediate this effect is unknown. In this paper, the authors review the literature regarding the safety of beta blockers in patients with TBI. The findings of several recent retrospective cohort studies are examined and implications for future investigation are discussed. Future questions to be addressed include: the specific indications for the use of beta blockers in patients with TBI, the optimal type and dose of beta blocker given, the end point of beta blocker therapy, and the safety of beta blockers in cases of severe TBIs.


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