The Association between T-Wave Morphology and Life-Threatening Ventricular Tachyarrhythmias in Patients with Congestive Heart Failure

2009 ◽  
Vol 32 (9) ◽  
pp. 1173-1177 ◽  
Author(s):  
YEN-HUNG LIN ◽  
LIAN-YU LIN ◽  
YING-SHREN CHEN ◽  
HUI-CHUN HUANG ◽  
JEN-KUANG LEE ◽  
...  
2021 ◽  
Vol 5 (6) ◽  
Author(s):  
Kyunghee Lim ◽  
Jong Sung Park ◽  
Byeol-A Yoon ◽  
Song-Hee Han

Abstract Background Necrotizing autoimmune myopathy is a rare subtype of idiopathic inflammatory myopathy; however, it can be associated with fatal cardiac manifestations. Case summary A 58-year-old female patient was referred for congestive heart failure with dysrhythmia. Electrocardiograms showed ventricular arrhythmias of various QRS complex morphologies and coupling intervals with beat-to-beat differences. Despite optimal medical therapy for heart failure, the patient was admitted for the progression of dyspnoea and generalized motor weakness. The burden of non-sustained ventricular tachycardia gradually increased, and ventricular fibrillation eventually occurred. In view of a differential diagnosis of an inflammatory myocardial diseases such as sarcoidosis, a cardiac biopsy was performed. However, pathologic examinations revealed only necrotic muscle fibres without granuloma. Further examinations revealed proximal dominant motor weakness, an elevated serum creatinine-phosphokinase level, myogenic potentials on needle electromyography, and biceps muscle biopsy findings that were compatible with necrotizing autoimmune myopathy. High-dose steroid therapy improved the patient’s motor weakness, including her respiratory impairment, and successfully suppressed ventricular arrhythmias. Discussion This case suggests that intensive immunosuppressive therapy with high-dose steroid could be useful in the necrotizing autoimmune myopathy manifested as congestive heart failure and life-threatening ventricular arrhythmias.


2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Maria Jesãºs Puchades Montesa ◽  
Nayara Panizo Gonzalez ◽  
Luis D'Marco ◽  
Miguel Gonzalez-Rico ◽  
Patricia Tomas ◽  
...  

Abstract Background and Aims Hyperkalemia (HK) is a potentially life-threatening condition, in patients with chronic kidney disease (CKD) and congestive heart failure (CHF). The majority of patients affected with CKD or CHF, must be treated with inhibitors of renin angiotensin aldosterone system (RAASi) and mineralocorticoid receptor antagonists (MRAs). However, the treatments previously mentioned, increase the risk of HK episodes, which is the main cause of RAASi and MRAs downtitration or discontinuation, representing an undesirable clinical scenario, given that the patients are at high risk of be deprived of their nephroprotective effect and cardio-renal benefits The aim of the study is: to analyze if, in patients with HK, CKD and CHF treated with RAASi and/or MRA, serum potassium (sK) reduction by Sodium zirconium cyclosilicate (SZC) treatment is non-inferior to RAASi and/or MRAs discontinuation or downtitration. Method Results The study will demonstrate results on serum electrolytes, renal function, albuminuria, KDQoL questionnaire and changes in relative overhydration (multifrequency bioimpedance -BCM Fresenius-) Conclusion The KEEP ON study will define the ability of SZC to facilitate the use of RAAS-I and / or MRA in patients with HK and cardiorenal syndrome allowing the maintenance of the medications recommended by international guidelines for the treatment of CHF at different degrees of CKD while maintaining the potential cardio-renal and nephroprotective benefit.


2004 ◽  
Vol 93 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Simona Sarzi Braga ◽  
Raffaella Vaninetti ◽  
Antonio Laporta ◽  
Anna Picozzi ◽  
Roberto F.E Pedretti

Author(s):  
Julia Ramírez ◽  
Michele Orini ◽  
Ana Mincholé ◽  
Violeta Monasterio ◽  
Iwona Cygankiewicz ◽  
...  

2019 ◽  
Vol 16 (3-4) ◽  
pp. 71-80
Author(s):  
A. M. Prasodo ◽  
M. Narendra ◽  
A. Joernil ◽  
Wahjoenarso Wahjoenarso ◽  
F. Kaspan

The picture of congestive heart failure in diphtheric myocarditis was mainly determined by poor general condition, hepatic enlargement + epigastric pain, dyspnea. Basal rales and peripheral edema were not observed. Cardiomegaly on X-ray examination supported the diagnosis. Congestive heart failure as a complication of diphtheric myocarditis occurred in 31.2% - 52% of cases with severe ECG changes and only in 5% of cases with ST depression or T wave changes. Of 29 cases with congestive heart failure only 3 survived. Apparently good results of digitalis treatment were obtained when only gallop rhythm, as an early sign of heart failure, was found. Extensive myocardial damage by diphtheria toxin may explain why no beneficial effect of digitalis treatment was obtained. Prophylactic digitalization before signs of congestive heart failure appeared, as suggested by several authors; was not performed in this study.


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