scholarly journals PERMANENT FECAL INCONTINENCE FOLLOWING BOTULINUM TOXIN INJECTION THERAPY FOR CHRONIC ANAL FISSURE

2003 ◽  
Vol 98 ◽  
pp. S146 ◽  
Author(s):  
Timothy D. Cassidy ◽  
Alejandro Pruitt ◽  
William B. Perry
Keyword(s):  
Botulinum Toxin ◽  
Fecal Incontinence ◽  
Anal Fissure ◽  
Chronic Anal Fissure ◽  
Botulinum Toxin Injection ◽  
Injection Therapy

scholarly journals Botulinum toxin injection versus internal anal sphincterotomy for the treatment of chronic anal fissure

2005 ◽  
Vol 25 (2) ◽  
pp. 140-142 ◽  
Author(s):  
Baghai-Wadji Massoud ◽  
Vahedian Mehrdad ◽  
Tolooie Baharak ◽  
Zohoor Alireza
Keyword(s):  
Botulinum Toxin ◽  
Anal Fissure ◽  
Chronic Anal Fissure ◽  
Botulinum Toxin Injection

Botulinum Toxin A with Fissurectomy is a Viable Alternative to Lateral Internal Sphincterotomy for Chronic Anal Fissure

2009 ◽  
Vol 75 (10) ◽  
pp. 925-928 ◽  
Author(s):  
Ohara Aivaz ◽  
Jessica Rayhanabad ◽  
Vincent Nguyen ◽  
Philip I. Haigh ◽  
Maher Abbas
Keyword(s):  
Botulinum Toxin ◽  
Fecal Incontinence ◽  
Anal Fissure ◽  
Chronic Anal Fissure ◽  
Botulinum Toxin A ◽  
Internal Sphincter ◽  
Viable Alternative ◽  
Lateral Internal Sphincterotomy ◽  
Toxin A ◽  
Internal Sphincterotomy

Lateral internal sphincterotomy (LIS) is the gold standard surgical treatment for anal fissure. However, it carries potential complications, including fecal incontinence. The goal of this retrospective study was to compare the outcome of botulinum toxin A injection coupled with fissurectomy ([BTX + FIS) versus LIS. There were 59 patients who underwent BTX + FIS or LIS over a 5-year period. LIS was performed in the standard fashion without fissurectomy. BTX + FIS entailed internal sphincter injection with 80 units of botulinum toxin A coupled with fissurectomy. Forty patients underwent LIS and 19 had BTX + FIS. The choice of operation was based on the patient's preference. Primary healing rate was 90 and 74 per cent in the LIS and BTX + FIS groups, respectively ( P = 0.13). The complication rate was 10 per cent in the LIS vs 0 per cent in the BTX + FIS groups ( P = 0.29). Complications of LIS included anal sepsis in one patient and flatal and/or fecal incontinence in three patients. During a mean follow up of 19 months; recurrence rate was 0 and 5 per cent in the LIS and BTX+FIS groups, respectively ( P = 0.32). The results of this study demonstrate that BTX + FIS is a viable alternative to LIS for patients with chronic anal fissure and should be considered as an alternative first-line surgical therapy.

Botulinum Toxin Injection Plus Topical Diltiazem for Chronic Anal Fissure

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Belen Herreros ◽  
Alejandro Espi ◽  
Cristina Montón ◽  
Eduardo García Granero ◽  
Vicente Sanchiz ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Anal Fissure ◽  
Chronic Anal Fissure ◽  
Botulinum Toxin Injection

scholarly journals Erratum to: Botulinum Toxin Injection for Treatment of Chronic Anal Fissure: Is There Any Dose-Dependent Efficiency? A Meta-Analysis

2016 ◽  
Vol 40 (12) ◽  
pp. 3063-3063 ◽  
Author(s):  
Adam Bobkiewicz ◽  
Wojciech Francuzik ◽  
Lukasz Krokowicz ◽  
Adam Studniarek ◽  
Witold Ledwosiński ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Anal Fissure ◽  
Chronic Anal Fissure ◽  
Meta Analysis ◽  
Botulinum Toxin Injection ◽  
Dose Dependent

scholarly journals A comparative study between lateral internal anal sphincterotomy and botulinum toxin injection in the treatment of chronic anal fissure

2021 ◽  
Vol 25 (2) ◽  
pp. 513-519
Author(s):  
Abdulqadir Zngana ◽  
Bawan Hiwa
Keyword(s):  
Botulinum Toxin ◽  
Comparative Study ◽  
Anal Fissure ◽  
Chronic Anal Fissure ◽  
Botulinum Toxin Injection ◽  
Lateral Internal Sphincterotomy ◽  
Internal Sphincterotomy ◽  
Hospitalization Period ◽  
Prospective Comparative Study ◽  
Group B

Background and objective: The gold standard for the treatment of chronic anal fissure is lateral internal sphincterotomy. Botulinum toxin injection provides temporary alleviation of sphincter spasm and allows the fissure to heal. This study aimed to compare the outcomes of lateral internal sphincterotomy and botulinum toxin injection treatments in patients with uncomplicated chronic anal fissure. Methods: A prospective comparative study was carried out at the surgical unit of Erbil teaching hospital, Erbil, Kurdistan Region of Iraq, from January 2017 to February 2018. Fifty-five patients were enrolled in this study. Five patients were excluded, and the remaining 50 patients were equally divided into two groups. Group A was managed with lateral internal sphincterotomy and group B with botulinum toxin. Postoperative pain relief, bleeding, fissure healing, incontinence, and relapse after six weeks and three months of follow-up were compared. Results: One month after treatment, 12% of the lateral internal sphincterotomy group had bleeding, while none of the botulinum toxin group (P = 0.234). Two patients (8%) of the lateral internal sphincterotomy group had pain while one (4%) of the botulinum toxin group (P >0.999).Three months after treatment, 4% of the lateral internal sphincterotomy group had bleeding, while none of the botulinum toxin group (P >0.999). None of the lateral internal sphincterotomy group had pain while one (4%) of the botulinum toxin group (P >0.999). Regarding healing, 96% of the lateral internal sphincterotomy group healed, while 92% in the botulinum toxin group (P >0.999). Conclusion: The outcome of lateral internal sphincterotomy and botulinum toxin were nearly the same, but lateral internal sphincterotomy required hospitalization, period off work, and risk of anesthesia. These risks were absent in botulinum toxin injection. Keywords: Chronic anal fissure; Lateral internal sphincterotomy; Botulinum toxin; Complications.

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