Non-sentinel lymph node involvement in a patient with an atypical Spitz tumor and a positive sentinel node. Report of a case and review of the literature

2009 ◽  
Vol 36 (5) ◽  
pp. 586-590 ◽  
Author(s):  
Carmelo Urso ◽  
Lorenzo Borgognoni ◽  
Morena Doria ◽  
Galliano Tinacci ◽  
Enzo Zini
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Node ◽  
Lymph Node Involvement ◽  
Positive Sentinel Node ◽  
Review Of The Literature ◽  
Node Involvement

Predictive Factors for Additional Non-Sentinel Lymph Node Involvement in Breast Cancer Patients with One Positive Sentinel Node

2015 ◽  
Vol 101 (1) ◽  
pp. 78-83 ◽  
Author(s):  
Icro Meattini ◽  
Calogero Saieva ◽  
Silvia Bertocci ◽  
Giulio Francolini ◽  
Giacomo Zei ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Node ◽  
Cancer Patients ◽  
Predictive Factors ◽  
Lymph Node Involvement ◽  
Positive Sentinel Node ◽  
Breast Cancer Patients ◽  
Node Involvement

The Microanatomic Location of Metastatic Melanoma in Sentinel Lymph Nodes Predicts Nonsentinel Lymph Node Involvement

2004 ◽  
Vol 22 (16) ◽  
pp. 3345-3349 ◽  
Author(s):  
D.J. Dewar ◽  
B. Newell ◽  
M.A. Green ◽  
A.P. Topping ◽  
B.W.E.M. Powell ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Node ◽  
Metastatic Melanoma ◽  
Sentinel Node Biopsy ◽  
Lymph Node Involvement ◽  
Positive Sentinel Node ◽  
Sentinel Nodes ◽  
Node Biopsy ◽  
Node Involvement ◽  
Nonsentinel Lymph Node

Purpose Sentinel node biopsy is now widely accepted as the most accurate prognostic indicator in melanoma, and is important in guiding management of patients with clinical stage I or II disease. Patients with a positive sentinel node have conventionally undergone completion lymphadenectomy (CLND) of the involved basin, but only 20% have involvement beyond the sentinel node, suggesting that CLND may be unnecessary for the other 80% of patients. This study seeks to identify criteria that might be used to be more restrictive in selecting those who should undergo CLND. Methods A total of 146 patients were identified who had had a positive sentinel node biopsy for malignant melanoma. Their sentinel nodes and lymphadenectomy specimens were re-evaluated pathologically. The metastatic melanoma in each sentinel node was assessed according to its microanatomic location within the node (subcapsular, combined subcapsular and parenchymal, parenchymal, multifocal, or extensive), and this was correlated with the presence of involved nonsentinel nodes in the CLND. The depth of the metastases from the sentinel node capsule was also recorded. Results The metastatic deposits in the sentinel node were subcapsular in 26.0% of patients. None of these patients had any nonsentinel nodes involved on CLND. In the patients whose sentinel node metastases had a different microanatomic location, the rate of nonsentinel node involvement was 22.2% overall. Conclusion The microanatomic location of metastases within sentinel nodes predicts nonsentinel lymph node involvement. In patients with only subcapsular deposits in the sentinel node, it is possible that CLND could safely be avoided.

305 Level III lymph node involvement cannot be predicted following positive sentinel node biopsy

2010 ◽  
Vol 8 (3) ◽  
pp. 147
Author(s):  
E.K. Romano ◽  
C.C. Kirwan ◽  
M.S. Absar ◽  
S. Pritchard ◽  
M. Wilson ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Lymph Node Involvement ◽  
Positive Sentinel Node ◽  
Node Biopsy ◽  
Node Involvement
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