Innate Vα14+natural killer T cells mature dendritic cells, leading to strong adaptive immunity

2007 ◽  
Vol 220 (1) ◽  
pp. 183-198 ◽  
Author(s):  
Shin-Ichiro Fujii ◽  
Kanako Shimizu ◽  
Hiroaki Hemmi ◽  
Ralph M. Steinman
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Natural Killer ◽  
Adaptive Immunity ◽  
Natural Killer T Cells ◽  
Killer T Cells ◽  
Natural Killer T

scholarly journals Co-accumulation of Dendritic Cells and Natural Killer T Cells within Rupture-prone Regions in Human Atherosclerotic Plaques

2005 ◽  
Vol 53 (6) ◽  
pp. 781-785 ◽  
Author(s):  
Yuri V. Bobryshev ◽  
Reginald S.A. Lord
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Natural Killer ◽  
Natural Killer T Cells ◽  
Nkt Cells ◽  
Atherosclerotic Plaques ◽  
Lipid Antigens ◽  
Atherosclerotic Lesions ◽  
Killer T Cells ◽  
Natural Killer T

We previously reported that CD1d, a molecule responsible for the presentation of lipid antigens, is expressed in atherosclerotic lesions and that its expression is restricted to dendritic cells. Recent studies demonstrating that CD1d-restricted natural killer T (NKT) cells are involved in atherogenesis prompted the present study investigating whether NKT cells are present in human atherosclerotic lesions and, if so, whether there is an association between NKT cells and dendritic cells. We found that NKT cells do accumulate in rupture-prone shoulders of atherosclerotic plaques and observed direct contacts of dendritic cells with NKT cells in rupture-prone regions of plaque.

Bacillus Calmette-Guérin-pulsed dendritic cells stimulate natural killer T cells and γδT cells

2007 ◽  
Vol 14 (6) ◽  
pp. 532-538 ◽  
Author(s):  
Michio Naoe ◽  
Yoshio Ogawa ◽  
Kumiko Takeshita ◽  
Jun Morita ◽  
Sanju Iwamoto ◽  
...  
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Natural Killer ◽  
Natural Killer T Cells ◽  
Bacillus Calmette Guerin ◽  
Γδt Cells ◽  
Killer T Cells ◽  
Natural Killer T
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