CLASSIFICATION OF MYCOBACTERIUM SIMIAE BY MEANS OF COMPARATIVE RECIPROCAL INTRADERMAL SENSITIN TESTING ON GUINEA-PIGS AND DEOXYRIBONUCLEIC ACID HYBRIDIZATION

2009 ◽  
Vol 90B (1-6) ◽  
pp. 101-107
Author(s):  
INGA BAESS ◽  
M. MAGNUSSON
Keyword(s):  
Guinea Pigs ◽  
Deoxyribonucleic Acid ◽  
Mycobacterium Simiae

SPECIES DIFFERENCES IN THE DEOXYRIBONUCLEIC AND RIBONUCLEIC ACID CONTENTS OF LIVERS OF NON-PREGNANT AND PREGNANT MICE, GUINEA-PIGS AND CATS

1953 ◽  
Vol 9 (1) ◽  
pp. 45-51 ◽  
Author(s):  
ROSA M. CAMPBELL ◽  
H. W. KOSTERLITZ
Keyword(s):  
Guinea Pig ◽  
Protein Content ◽  
Liver Cell ◽  
Ribonucleic Acid ◽  
Guinea Pigs ◽  
Deoxyribonucleic Acid ◽  
Species Differences ◽  
Liver Cells ◽  
Maternal Liver ◽  
Pregnant Mice

1. The protein content of liver cells is almost independent of the size of the animal (mice, cats and previous results on rats, Campbell & Kosterlitz [1949]), and varies with the amount of protein eaten. 2. As has already been shown for rats, the ribonucleic acid ('RNA') content of the liver cells of non-pregnant mice, guinea-pigs and cats varies directly with the protein content of the cells. For a given protein content the mouse and rat have more RNA than the guinea-pig and cat. 3. During pregnancy there is a rise of the deoxyribonucleic acid ('DNA') content of the livers and in the protein content of the liver cells of mice (and rats), but not of guinea-pigs. 4. An excess of RNA over that predicted from the protein content of the liver cell has previously been found for the rat during pregnancy, and ascribed to the action of a placental factor on the maternal liver. A similar excess of RNA has now been observed in the mouse and, to a less extent, in the guinea-pig. It appears to be absent in the cat. 5. Possible causes of some of these species differences are considered.

scholarly journals MULTIPLICATION AND SURVIVAL OF TUBERCLE BACILLI IN THE ORGANS OF MICE

1953 ◽  
Vol 97 (2) ◽  
pp. 189-206 ◽  
Author(s):  
Cynthia H. Pierce ◽  
René J. Dubos ◽  
Werner B. Schaefer
Keyword(s):  
Peritoneal Cavity ◽  
Guinea Pigs ◽  
Bacterial Population ◽  
Progressive Disease ◽  
Blood Stream ◽  
Experimental Animals ◽  
Virulent Strains ◽  
Different Levels

Cultures of tubercle bacilli (typical bovine and human strains) known to differ in the severity of the lesions they induce in experimental animals, were injected in various doses into the cerebrum, peritoneal cavity, or blood stream of mice. Quantitative determinations of the numbers of living bacilli present in the tissues at different intervals of time after infection led to the following classification of the cultures tested:— (a) Certain well known variant forms of tubercle bacilli were found to be unable to multiply in vivo, although they could survive for many weeks in the tissues of mice. These organisms proved to be truly avirulent. (b) Other variant forms underwent multiplication in vivo, even when extremely small infective doses were used, but could not give rise to progressive disease. It is proposed to designate these strains, which produce only abortive infections, as "attenuated." Different levels of attenuation could be detected. The maximum numbers of living bacilli that were recovered from the tissues corresponded directly to the severity and duration of the abortive lesions that could be produced by the strain in guinea pigs or in mice and were characteristic for each strain tested. The two BCG substrains tested were found to differ markedly in their level of attenuation. (c) The cultures virulent for guinea pigs were also capable of establishing a progressive infection in mice even when small infective doses were used. In the case of the attenuated and virulent strains, the population of living bacilli present in the lungs was at first much lower than that in the spleen, but it continued to increase in the former organs throughout the period of observation. This was notably true in the case of the virulent cultures. In contrast, the numbers of living bacilli in the spleen rapidly reached a maximum in the case of all cultures and then decreased progressively. For a given infective dose, and a given interval of time after inoculation, the maximum levels of living bacterial population attained in the spleen and in the lungs proved to be a direct expression of the virulence of the strain.

scholarly journals Deoxyribonucleic Acid Reassociation in the Classification of the Genus Rhodococcus Zopf 1891 (Approved Lists, 1980)

1980 ◽  
Vol 30 (3) ◽  
pp. 521-527 ◽  
Author(s):  
M. MORDARSKI ◽  
M. GOODFELLOW ◽  
I. KASZEN ◽  
A. TKACZ ◽  
G. PULVERER ◽  
...  
Keyword(s):  
Deoxyribonucleic Acid

scholarly journals Classification of Micrococci on the Basis of Deoxyribonucleic Acid Homology

1976 ◽  
Vol 94 (1) ◽  
pp. 97-106 ◽  
Author(s):  
N. Ogasawara-Fujita ◽  
K. Sakaguchi
Keyword(s):  
Deoxyribonucleic Acid

scholarly journals The Concept and Classification of Genomic (Genetic) Information

Lex Russica ◽  
2020 ◽  
pp. 50-58
Author(s):  
M. N. Maleina
Keyword(s):  
Ribonucleic Acid ◽  
Genetic Information ◽  
Biological Sample ◽  
Deoxyribonucleic Acid ◽  
Personal Data ◽  
Genomic Information ◽  
Genomic Technologies ◽  
And Storage ◽  
Living Being

The importance of genomic information has now increased due to the possibility of its practical use. Meanwhile, the understanding of the term “genomic information” is specified based on different criteria. Genomic information is proposed to be classified depending on the following criteria: 1) the origin of a biological sample, 2) the place of fixation and storage of genomic information, 3) the purpose of use, 4) the completeness of examination, 5) the relation of a person to the acquisition of his or her genomic information, 6) the scope of content. Genomic information can be presented as a generic concept referring to all biological objects, as a special concept (species) referring only to humans, and as subspecies reflecting specificity of such information in a particular area of activity. Genomic information of a living being (human, animal, plant, microorganism) is understood as data on certain fragments of deoxyribonucleic acid (sometimes ribonucleic acid) on the basis of which the living being is identified or other permitted activity is carried out.Human genomic information is defined as biometric personal data extracted from certain fragments of deoxyribonucleic acid (sometimes ribonucleic acid) of a living individual or corpse, on the basis of which it is possible to identify, determine genetic predispositions or extract patterns of the development of the human being obtained voluntarily, and, in cases provided for by the law, forced to be fixed in a biological sample and/or stored in an information map or database.It is proved that the existing laws on information or a new law dedicated to regulation of the application of genomic technologies should be amended instead of adopting a special law “On Genetic Information”. 

scholarly journals Classification of the "Rhodochrous" Complex and Allied Taxa Based upon Deoxyribonucleic Acid Reassociation

1977 ◽  
Vol 27 (1) ◽  
pp. 31-37 ◽  
Author(s):  
M. MORDARSKI ◽  
M. GOODFELLOW ◽  
K. SZYBA ◽  
G. PULVERER ◽  
A. TKACZ
Keyword(s):  
Deoxyribonucleic Acid

scholarly journals Deoxyribonucleic Acid Reassociation in the Classification of the 'rhodochrous' Complex and Allied Taxa

1976 ◽  
Vol 94 (2) ◽  
pp. 235-245 ◽  
Author(s):  
M. Mordarski ◽  
K. Szyba ◽  
G. Pulverer ◽  
M. Goodfellow
Keyword(s):  
Deoxyribonucleic Acid
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