The tetrapeptide acetyl-serine-aspartyl-lysine-proline improves skin flap survival and accelerates wound healing

2006 ◽  
Vol 14 (3) ◽  
pp. 306-312 ◽  
Author(s):  
Yves Fromes ◽  
Jian-Miao Liu ◽  
Milica Kovacevic ◽  
Jérôme Bignon ◽  
Joanna Wdzieczak-Bakala
Keyword(s):  
Wound Healing ◽  
Skin Flap ◽  
Flap Survival ◽  
Skin Flap Survival

scholarly journals Photocrosslinked gelatin hydrogel improves wound healing and skin flap survival by the sustained release of basic fibroblast growth factor

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Toshihiro Kushibiki ◽  
Yoshine Mayumi ◽  
Eiko Nakayama ◽  
Ryuichi Azuma ◽  
Kenichiro Ojima ◽  
...  
Keyword(s):  
Wound Healing ◽  
Sustained Release ◽  
Visible Light ◽  
Skin Flap ◽  
Ease Of Use ◽  
Light Irradiation ◽  
Potential Candidate ◽  
Flap Survival ◽  
Gelatin Hydrogel ◽  
Skin Flap Survival

AbstractBiomaterials traditionally used for wound healing can act as a temporary barrier to halt bleeding, prevent infection, and enhance regeneration. Hydrogels are among the best candidates for wound healing owing to their moisture retention and drug-releasing properties. Photo-polymerization using visible light irradiation is a promising method for hydrogel preparation since it can easily control spatiotemporal reaction kinetics and rapidly induce a single-step reaction under mild conditions. In this study, photocrosslinked gelatin hydrogels were imparted with properties namely fast wound adherence, strong wet tissue surface adhesion, greater biocompatibility, long-term bFGF release, and importantly, ease of use through the modification and combination of natural bio-macromolecules. The production of a gelatin hydrogel made of natural gelatin (which is superior to chemically modified gelatin), crosslinked by visible light, which is more desirable than UV light irradiation, will enable its prolonged application to uneven wound surfaces. This is due to its flexible shape, along with the administration of cell growth factors, such as bFGF, for tissue regeneration. Further, the sustained release of bFGF enhances wound healing and skin flap survival. The photocrosslinking gelatin hydrogel designed in this study is a potential candidate to enhance wound healing and better skin flap survival.

The Effects of Vasonatrin Peptide on Random Pattern Skin Flap Survival

2014 ◽  
Vol 72 (1) ◽  
pp. 94-99 ◽  
Author(s):  
Shi-Ping Wang ◽  
Zhi-Yong Lan ◽  
Wei Xia ◽  
Xi Zhao ◽  
Ge-Jia Ma ◽  
...  
Keyword(s):  
Skin Flap ◽  
Random Pattern ◽  
Flap Survival ◽  
Skin Flap Survival

Effect of Aspirin and Heparin on Random Skin Flap Survival in Rats

2008 ◽  
Vol 34 (6) ◽  
pp. 785-790 ◽  
Author(s):  
AVSHALOM SHALOM ◽  
TAL FRIEDMAN ◽  
MELVYN WESTREICH
Keyword(s):  
Skin Flap ◽  
Flap Survival ◽  
Skin Flap Survival

Improved skin flap survival with nicotinic acid and nicotinamide in rats

1990 ◽  
Vol 86 (6) ◽  
pp. 1249
Author(s):  
John C. Kelleher ◽  
M. J. Im ◽  
J. E. Hoopes
Keyword(s):  
Nicotinic Acid ◽  
Skin Flap ◽  
Flap Survival ◽  
Skin Flap Survival

The effect of phenoxybenzamine, phentolamine and 6-hydroxydopamine on skin flap survival in rats

1975 ◽  
Vol 19 (2) ◽  
pp. 83-87 ◽  
Author(s):  
M.R. Wexler ◽  
M. Kalisman ◽  
R. Yeschua ◽  
Z. Neuman
Keyword(s):  
Skin Flap ◽  
Flap Survival ◽  
Skin Flap Survival ◽  
6 Hydroxydopamine

scholarly journals Inducible nitric oxide synthase (iNOS) activity promotes ischaemic skin flap survival

2001 ◽  
Vol 132 (8) ◽  
pp. 1631-1638 ◽  
Author(s):  
Anthony J Kane ◽  
Jane E Barker ◽  
Geraldine M Mitchell ◽  
David R B Theile ◽  
Rosalind Romero ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Inducible Nitric Oxide Synthase ◽  
Skin Flap ◽  
Inos Activity ◽  
Flap Survival ◽  
Skin Flap Survival ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide
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