Cytomegalovirus Antibodies in Endolymphatic Sac Biopsies of Patients with Endolymphatic Hydrops and Ménière's Disease

1997 ◽  
Vol 830 (1) ◽  
pp. 314-318 ◽  
Author(s):  
I. KAUFMAN ARENBERG ◽  
GARY CABRIAC ◽  
STEFAN MARKS ◽  
JULIE G. ARENBERG ◽  
PETER R. PFEIFFER ◽  
...  
Neurosurgery ◽  
2008 ◽  
Vol 63 (5) ◽  
pp. E1001-E1001 ◽  
Author(s):  
Daniel H. Coelho ◽  
J. Thomas Roland ◽  
John G. Golfinos

Abstract OBJECTIVE AND IMPORTANCE In rare cases, posterior fossa meningiomas can involve the endolymphatic sac. Such involvement can result in endolymphatic hydrops and a constellation of symptoms suggestive of Ménière's disease. The diagnosis and management of patients with these tumors is discussed. CLINICAL PRESENTATION Three patients, each of whom presented with symptoms consistent with Ménière's disease, were found to have posterior fossa meningiomas limited to the dura overlying the endolymphatic sac. INTERVENTION All 3 patients were diagnosed by magnetic resonance imaging and underwent complete surgical resection. In all cases, the symptoms resolved after tumor removal. CONCLUSION Clinicians should have a degree of suspicion of posterior fossa meningioma when patients present with symptoms suggestive of Ménière's disease. Failure to do so may result in delayed diagnosis or worse outcomes for an otherwise treatable tumor.


2017 ◽  
Vol 21 (02) ◽  
pp. 179-183 ◽  
Author(s):  
Maria Flores García ◽  
Carolina Llata Segura ◽  
Juan Cisneros Lesser ◽  
Carlo Pane Pianese

Introduction The endolymphatic sac is thought to maintain the hydrostatic pressure and endolymph homeostasis for the inner ear, and its dysfunction may contribute to the pathophysiology of Ménière's disease. Throughout the years, different surgical procedures for intractable vertigo secondary to Ménière's disease have been described, and though many authors consider these procedures as effective, there are some who question its long-term efficacy and even those who think that vertigo control is achieved more due to a placebo effect than because of the procedure itself. Objective To review the different surgical procedures performed in the endolymphatic sac for the treatment of Ménière's disease. Data Sources PubMed, MD consult and Ovid-SP databases. Data Synthesis We focus on describing the different surgical procedures performed in the endolymphatic sac, such as endolymphatic sac decompression, endolymphatic sac enhancement, endolymphatic sac shunting and endolymphatic duct blockage, their pitfalls and advantages, their results in vertigo control and the complication rates. The senior author also describes his experience after 30 years of performing endolymphatic sac surgery. Conclusions The endolymphatic sac surgery, with all its variants, is a good option for patients with incapacitating endolymphatic hydrops, providing a high percentage of vertigo control and hearing preservation.


Author(s):  
I. Kaufman Arenberg ◽  
E. Rauchbach ◽  
J.P. Murray ◽  
G.J. Spector

The role of the endolymphatic sac (ELS) in the pathogenesis of endolymphatic hydrops (ELH) or Meniere's disease is considered of great importance. An experimental model of ELH, the histopathologic correlate of Meniere's disease, has been utilized to study the effect of excess endolymph and endolymphatic hypertension on the inner ear of the lemon shark (Negation brevirostris). This study investigates the changes which occur to the ELS when the ELH is produced either by cautery of the external endolymphatic duct (ELD) orifice or by ligature of the external ELD after 6 weeks to 6 months postoperatively. All specimens (n = 4 normal n = 6 cautery hydrops, n = 4 ligature hydrops) were routinely prepared for SEM by the critical point method of Smith and Finke and photographed at 20 KV on a Cambridge Stereoscan Mark II. The normal intermediate portion of the ELS shows multiple rugae or folds and true villi (Fig. 1) to increase surface area for the resorbtion of endolymph.


1985 ◽  
Vol 66 (6) ◽  
pp. 442-444
Author(s):  
I. P. Firsova

Currently, endolymphatic hydrops is considered a morphological substrate of Meniere's disease.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Munehisa Fukushima ◽  
Yu Suekata ◽  
Takuya Kusumoto ◽  
Shiro Akahani ◽  
Hidehiko Okamoto ◽  
...  

2009 ◽  
Vol 129 (11) ◽  
pp. 1326-1329 ◽  
Author(s):  
Maiko Miyagawa ◽  
Hisakuni Fukuoka ◽  
Keita Tsukada ◽  
Tomohiro Oguchi ◽  
Yutaka Takumi ◽  
...  

1982 ◽  
Vol 90 (4) ◽  
pp. 470-481 ◽  
Author(s):  
Masaaki Kitahara ◽  
Taizo Takeda ◽  
Yoshiro Yazawa ◽  
Hideharu Matsubara ◽  
Hitoshi Kitano

Experimental hydrops caused by underabsorption of endolymphatic fluid is a model of remissional stage of Meniere's disease. In this study, another type of model, ie, hydrops caused by overproduction of endolymphatic fluid, was accomplished by applying various pressures into scala media through a micropipette via stria vascularis. This type of hydrops could be a model of attacks of Meniere's disease. By using two types of the model, effects of glycerol administration and of opening the endolymphatic sac were discussed.


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