THE REPAIR OF DNA STRAND BREAKS IN HUMAN LYMPHOCYTES EXPOSED TO NEAR UV-RADIATION (UVA) AND FAR UV-RADIATION (UVC)

1985 ◽  
Vol 41 (4) ◽  
pp. 437-444 ◽  
Author(s):  
M. Holmberg ◽  
Zs. Almássy ◽  
M. Lagerberg ◽  
B. Niejahr
Keyword(s):  
Uv Radiation ◽  
Human Lymphocytes ◽  
Dna Strand Breaks ◽  
Strand Breaks ◽  
Dna Strand

Rapid Rejoining of DNA Strand Breaks in Resting Human Lymphocytes after Irradiation by Low Doses of 60 Co g Rays or 14.6-MeV Neutrons

1983 ◽  
Vol 94 (3) ◽  
pp. 499 ◽  
Author(s):  
R. S. McWilliams ◽  
W. G. Cross ◽  
J. G. Kaplan ◽  
H. C. Birnboim
Keyword(s):  
Human Lymphocytes ◽  
Dna Strand Breaks ◽  
Low Doses ◽  
Strand Breaks ◽  
Dna Strand

Induction and disappearance of DNA strand breaks and/or alkalilabile sites in human lymphocytes exposed to N-ethyl-N-nitrosourea

1991 ◽  
Vol 12 (1) ◽  
pp. 77-82 ◽  
Author(s):  
Michael E.T.I. Boerrigter ◽  
Erik Mullaart ◽  
Frits Berends ◽  
Jan Vijg
Keyword(s):  
Human Lymphocytes ◽  
Dna Strand Breaks ◽  
Strand Breaks ◽  
Dna Strand

Induction of DNA Strand Breaks in Peripheral Lymphocytes by Soluble Chromium Compounds

1992 ◽  
Vol 11 (2) ◽  
pp. 77-82 ◽  
Author(s):  
M. Gao ◽  
S.P. Binks ◽  
J.K. Chipman ◽  
L.S. Levy ◽  
R.A. Braithwaite ◽  
...  
Keyword(s):  
Human Lymphocytes ◽  
Intratracheal Instillation ◽  
Dna Strand Breaks ◽  
Sodium Dichromate ◽  
Strand Breaks ◽  
Peripheral Lymphocytes ◽  
Occupationally Exposed ◽  
Dna Strand ◽  
Dose Dependent Increase ◽  
Chromium Acetate

1 Incubation of human lymphocytes with sodium dichromate (CrVI) at 37°C for 3 h resulted in a dose-dependent increase in DNA strand breaks without concurrent cytotoxicity. In contrast, chromium acetate hydroxide (CrIII) failed to induce DNA strand breaks at sub-cytotoxic concentrations. 2 DNA strand breaks were also detected in the peripheral lymphocytes of Wistar rats, 24 h after intratracheal instillation of sodium dichromate (1.3 and 2.5 mg kg-1 ). Instillation of chromium acetate hydroxide (up to 21.8 mg kg -1) failed to induce DNA strand breaks in peripheral lymphocytes. In accord with previous studies, hexavalent chromium was found to be more readily absorbed from the lungs into the peripheral blood than chromium in its trivalent form. 3 The results of this study indicate that fluorometric analysis of DNA unwinding (FADU) in peripheral lymphocytes might be a convenient method of measuring an important biological effect of chromium in occupationally-exposed workers.

Styrene oxide-induced HPRT mutations, DNA adducts and DNA strand breaks in cultured human lymphocytes

1995 ◽  
Vol 16 (10) ◽  
pp. 2357-2362 ◽  
Author(s):  
Tatiana Bastlová ◽  
Pavel Vodička ◽  
Kateřrina Peterková ◽  
Kari Hemminki ◽  
Bo Lambert
Keyword(s):  
Dna Adducts ◽  
Styrene Oxide ◽  
Human Lymphocytes ◽  
Dna Strand Breaks ◽  
Strand Breaks ◽  
Dna Strand
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