Right atrial conduction time for predicting coexistent typical atrial flutter in patients with paroxysmal atrial fibrillation

2020 ◽  
Vol 31 (9) ◽  
pp. 2355-2362
Author(s):  
Satoshi Higuchi ◽  
Koichiro Ejima ◽  
Morio Shoda ◽  
Miwa Kanai ◽  
Shohei Kataoka ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Atrial Flutter ◽  
Paroxysmal Atrial Fibrillation ◽  
Right Atrial ◽  
Conduction Time ◽  
Typical Atrial Flutter ◽  
Atrial Conduction Time

Cardiac magnetic resonance-derived right atrial functional analysis in patients with atrial fibrillation and typical atrial flutter

2019 ◽  
Vol 59 (2) ◽  
pp. 381-391
Author(s):  
Esra Gucuk Ipek ◽  
Mohammadali Habibi ◽  
Tarek Zghaib ◽  
Stefan L. Zimmerman ◽  
Hugh Calkins ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Functional Analysis ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Atrial Flutter ◽  
Right Atrial ◽  
Typical Atrial Flutter

scholarly journals Comparison of the effects of IK,ACh, IKr, and INa block in conscious dogs with atrial fibrillation and on action potentials in remodeled atrial trabeculae

2018 ◽  
Vol 96 (1) ◽  
pp. 18-25 ◽  
Author(s):  
Viktor Juhász ◽  
Tibor Hornyik ◽  
Attila Benák ◽  
Norbert Nagy ◽  
Zoltán Husti ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Action Potentials ◽  
Qt Interval ◽  
Structural Heart Disease ◽  
Conscious Dogs ◽  
Right Atrial ◽  
Conduction Time ◽  
Antiarrhythmic Agents ◽  
Atrial Conduction Time

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and a major cause of morbidity and mortality. Traditional antiarrhythmic agents used for restoration of sinus rhythm have limited efficacy in long-term AF and they may possess ventricular proarrhythmic adverse effects, especially in patients with structural heart disease. The acetylcholine receptor-activated potassium channel (IK,ACh) represents an atrial selective target for future AF management. We investigated the effects of the IK,ACh blocker tertiapin-Q (TQ), a derivative of the honeybee toxin tertiapin, on chronic atrial tachypacing-induced AF in conscious dogs, without the influence of anesthetics that modulate a number of cardiac ion channels. Action potentials (APs) were recorded from right atrial trabeculae isolated from dogs with AF. TQ significantly and dose-dependently reduced AF incidence and AF episode duration, prolonged atrial effective refractory period, and prolonged AP duration. The reference drugs propafenone and dofetilide, both used in the clinical management of AF, exerted similar effects against AF in vivo. Dofetilide prolonged atrial AP duration, whereas propafenone increased atrial conduction time. TQ and propafenone did not affect the QT interval, whereas dofetilide prolonged the QT interval. Our results show that inhibition of IK,ACh may represent a novel, atrial-specific target for the management of AF in chronic AF.

scholarly journals 1025-100 Patients with WPW Syndrome and Paroxysmal Atrial Fibrillation Shows Prolonged Atrial Conduction Time by Signal-Averaged P-Wave Electrocardiogram

1995 ◽  
Vol 25 (2) ◽  
pp. 406A-407A
Author(s):  
Roberto Sá ◽  
Ivan G. Maia ◽  
Fernando Cruz F° ◽  
Silvia Boghossian ◽  
Marcio Fagundes ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Paroxysmal Atrial Fibrillation ◽  
P Wave ◽  
Conduction Time ◽  
Wpw Syndrome ◽  
Atrial Conduction Time

Characterization of Low Right Atrial Isthmus as the Slow Conduction Zone and Pharmacological Target in Typical Atrial Flutter

Circulation ◽  
1997 ◽  
Vol 96 (8) ◽  
pp. 2601-2611 ◽  
Author(s):  
Ching-Tai Tai ◽  
Shih-Ann Chen ◽  
Chern-En Chiang ◽  
Shih-Huang Lee ◽  
Kwo-Chang Ueng ◽  
...  
Keyword(s):  
Atrial Flutter ◽  
Right Atrial ◽  
Slow Conduction ◽  
Typical Atrial Flutter ◽  
Pharmacological Target ◽  
Conduction Zone
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