Randomized, double-blind, placebo-controlled, multiple-dose study of the safety, tolerability and pharmacokinetics of benvitimod, a candidate drug for the treatment of psoriasis

L. Zhao; X. Chen; L. Cai; C. Zhang; Q. Wang; S. Jing; G. Chen; J. Li; J. Zhang; Y. Fang

doi:10.1111/jcpt.12158

Randomized, double-blind, placebo-controlled, multiple-dose study of the safety, tolerability and pharmacokinetics of benvitimod, a candidate drug for the treatment of psoriasis

Journal of Clinical Pharmacy and Therapeutics ◽

10.1111/jcpt.12158 ◽

2014 ◽

Vol 39 (4) ◽

pp. 418-423 ◽

Cited By ~ 6

Author(s):

L. Zhao ◽

X. Chen ◽

L. Cai ◽

C. Zhang ◽

Q. Wang ◽

...

Keyword(s):

Multiple Dose ◽

Double Blind ◽

Double Blind Placebo ◽

Multiple Dose Study ◽

Candidate Drug ◽

Dose Study

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Fontolizumab in moderate to severe Crohnʼs disease: A phase 2, randomized, double-blind, placebo-controlled, multiple-dose study

Inflammatory Bowel Diseases ◽

10.1002/ibd.21038 ◽

2010 ◽

Vol 16 (2) ◽

pp. 233-242 ◽

Cited By ~ 137

Author(s):

Walter Reinisch ◽

Williem de Villiers ◽

László Bene ◽

László Simon ◽

István Rácz ◽

...

Keyword(s):

Multiple Dose ◽

Phase 2 ◽

Double Blind ◽

Double Blind Placebo ◽

Multiple Dose Study ◽

Dose Study

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Effects of Lixivaptan, a Novel Vasopressin V2 Receptor Antagonist, in Chronic Heart Failure: Results from a Double-Blind, Placebo-Controlled, Multiple-Dose Study

Journal of Cardiac Failure ◽

10.1016/j.cardfail.2008.06.193 ◽

2008 ◽

Vol 14 (6) ◽

pp. S71

Author(s):

William Abraham ◽

Steven Goldsmith ◽

Stephen Gottlieb

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Multiple Dose ◽

Double Blind ◽

Double Blind Placebo ◽

Multiple Dose Study ◽

Dose Study ◽

V2 Receptor ◽

Vasopressin V2 Receptor Antagonist ◽

V2 Receptor Antagonist

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Effects of RG7652, a fully human mAb against proprotein convertase subtilisin/kexin type 9, on LDL-c: a Phase I, randomised, double-blind, placebo-controlled, single- and multiple-dose study

European Heart Journal ◽

10.1093/eurheartj/eht309.p4183 ◽

2013 ◽

Vol 34 (suppl 1) ◽

pp. P4183-P4183 ◽

Cited By ~ 4

Author(s):

W. Tingley ◽

D. Luca ◽

M. Leabman ◽

N. Budha ◽

R. Kahn ◽

...

Keyword(s):

Phase I ◽

Multiple Dose ◽

Proprotein Convertase ◽

Double Blind ◽

Double Blind Placebo ◽

Multiple Dose Study ◽

Dose Study

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EFFECTS OF AMG 145, A FULLY HUMAN MONOCLONAL ANTIBODY AGAINST PCSK9, ON LOW-DENSITY LIPOPROTEIN CHOLESTEROL IN SUBJECTS TAKING STATINS: A PHASE 1, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, ASCENDING MULTIPLE-DOSE STUDY

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(12)61380-1 ◽

2012 ◽

Vol 59 (13) ◽

pp. E1379 ◽

Cited By ~ 16

Author(s):

Clapton Dias ◽

Adam Shaywitz ◽

Blaire Cooke ◽

Stephen Uy ◽

Maurice Emery ◽

...

Keyword(s):

Multiple Dose ◽

Phase 1 ◽

Low Density Lipoprotein ◽

Human Monoclonal Antibody ◽

Density Lipoprotein ◽

Low Density Lipoprotein Cholesterol ◽

Double Blind ◽

Double Blind Placebo ◽

Multiple Dose Study ◽

Dose Study

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P4-218: A phase I, double-blind, placebo-controlled, randomized, multiple dose study to evaluate the safety, tolerability, and pharmacokinetics of PF 04447943 in mild-to-moderate Alzheimer's disease subjects on stable donepezil therapy

Alzheimer s & Dementia ◽

10.1016/j.jalz.2011.05.2241 ◽

2011 ◽

Vol 7 ◽

pp. S781-S781

Author(s):

Rebecca Evans ◽

Timothy Nicholas ◽

Vu Le ◽

William Martin ◽

David Martin ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Phase I ◽

Multiple Dose ◽

Double Blind ◽

Double Blind Placebo ◽

Multiple Dose Study ◽

Dose Study

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GW24-e2907 Effects of RG7652, a fully human mAb against proprotein convertase subtilisin/kexin type 9, on LDL-c: a Phase I, randomised, double-blind, placebo-controlled, single- and multiple-dose study

Heart ◽

10.1136/heartjnl-2013-304613.423 ◽

2013 ◽

Vol 99 (Suppl 3) ◽

pp. A153.2-A153 ◽

Cited By ~ 1

Author(s):

Whittemore Tingley ◽

Diana Luca ◽

Maya Leabman ◽

Nageshwar Budha ◽

Robert Kahn ◽

...

Keyword(s):

Phase I ◽

Multiple Dose ◽

Proprotein Convertase ◽

Double Blind ◽

Double Blind Placebo ◽

Multiple Dose Study ◽

Dose Study

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Pharmacokinetic, pharmacodynamic, and tolerability profiles of the dipeptidyl peptidase-4 inhibitor alogliptin: A randomized, double-blind, placebo-controlled, multiple-dose study in adult patients with type 2 diabetes

Clinical Therapeutics ◽

10.1016/j.clinthera.2008.03.004 ◽

2008 ◽

Vol 30 (3) ◽

pp. 499-512 ◽

Cited By ~ 90

Author(s):

P COVINGTON ◽

R CHRISTOPHER ◽

M DAVENPORT ◽

P FLECK ◽

Q MEKKI ◽

...

Keyword(s):

Type 2 Diabetes ◽

Multiple Dose ◽

Dipeptidyl Peptidase ◽

Double Blind ◽

Double Blind Placebo ◽

Dipeptidyl Peptidase 4 ◽

Multiple Dose Study ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Dose Study

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A Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the Safety, Tolerability, and Efficacy of Brodalumab (AMG 827) in Subjects with Moderate to Severe Asthma

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2012.12.1486 ◽

2013 ◽

Vol 131 (2) ◽

pp. AB230 ◽

Cited By ~ 4

Author(s):

William W. Busse ◽

Stephen T. Holgate ◽

Edward M. Kerwin ◽

Yun Chon ◽

JingYuan Feng ◽

...

Keyword(s):

Severe Asthma ◽

Multiple Dose ◽

Double Blind ◽

Double Blind Placebo ◽

Multiple Dose Study ◽

Dose Study

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(210) Results from a phase I, double-blind, randomized, placebo-controlled, multiple-dose study evaluating the safety, tolerability, and pharmacokinetics of oral doses of NKTR-118

Journal of Pain ◽

10.1016/j.jpain.2008.01.131 ◽

2008 ◽

Vol 9 (4) ◽

pp. 28 ◽

Cited By ~ 4

Author(s):

D. Sahner ◽

H. van Paaschen ◽

A. Marcantonio ◽

M. Eldon

Keyword(s):

Phase I ◽

Multiple Dose ◽

Double Blind ◽

Multiple Dose Study ◽

Dose Study ◽

Oral Doses

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Brief Report: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multiple-Dose Study to Evaluate AMG 557 in Patients With Systemic Lupus Erythematosus and Active Lupus Arthritis

Arthritis & Rheumatology ◽

10.1002/art.40479 ◽

2018 ◽

Vol 70 (7) ◽

pp. 1071-1076 ◽

Cited By ~ 20

Author(s):

Laurence E. Cheng ◽

Zahir Amoura ◽

Benjamin Cheah ◽

Falk Hiepe ◽

Barbara A. Sullivan ◽

...

Keyword(s):

Systemic Lupus Erythematosus ◽

Lupus Erythematosus ◽

Multiple Dose ◽

Systemic Lupus ◽

Double Blind ◽

Multiple Dose Study ◽

Parallel Group ◽

Dose Study ◽

Active Lupus

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