TNFAIP3 and IL12B gene polymorphisms associated with psoriasis vulgaris in an Egyptian cohort

2014 ◽  
Vol 29 (7) ◽  
pp. 1297-1301 ◽  
Author(s):  
O. Haase ◽  
H. Mosaad ◽  
M.A. Eldarouti ◽  
A.Z. Elramly ◽  
N. Samir ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Psoriasis Vulgaris ◽  
Il12b Gene

AB0050 Association of il12b gene polymorphisms with ankylosing spondylitis

2013 ◽  
Vol 72 (Suppl 3) ◽  
pp. A800.4-A801
Author(s):  
M. Ivanova ◽  
I. Manolova ◽  
L. Miteva ◽  
N. Stoilov ◽  
R. Stoilov ◽  
...  
Keyword(s):  
Ankylosing Spondylitis ◽  
Gene Polymorphisms ◽  
Il12b Gene

CTLA-4 gene polymorphisms and natural soluble CTLA-4 protein in psoriasis vulgaris

2006 ◽  
Vol 33 (3) ◽  
pp. 217-224 ◽  
Author(s):  
W. Łuszczek ◽  
W. Kubicka ◽  
M. Jasek ◽  
E. Baran ◽  
M. Cisło ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Psoriasis Vulgaris

scholarly journals IL-6 and IL-10 Promoter Gene Polymorphisms in Psoriasis Vulgaris

2008 ◽  
Vol 88 (2) ◽  
pp. 113-116 ◽  
Author(s):  
W Baran ◽  
JC Szepietowski ◽  
G Mazur ◽  
E Baran
Keyword(s):  
Gene Polymorphisms ◽  
Psoriasis Vulgaris ◽  
Promoter Gene

Association of IL12B Gene Polymorphisms with Rheumatoid Arthritis: A Meta-analysis

2016 ◽  
Vol 47 (2) ◽  
pp. 126-133
Author(s):  
Ming-jie Wang ◽  
Xiao-liang Xu ◽  
Yuan-yuan Mi ◽  
Rui-ping Liu
Keyword(s):  
Rheumatoid Arthritis ◽  
Gene Polymorphisms ◽  
Meta Analysis ◽  
Il12b Gene

scholarly journals Association Study of the Caspase Gene Family and Psoriasis Vulgaris Susceptibility in Northeastern China

2019 ◽  
Vol 2019 ◽  
pp. 1-11
Author(s):  
Xinyu Yao ◽  
Siyu Hao ◽  
Pei Yu
Keyword(s):  
Gene Polymorphisms ◽  
Psoriasis Vulgaris ◽  
Disease Risk ◽  
Association Studies ◽  
Group Versus ◽  
Northeastern China ◽  
Control Group ◽  
Case Group ◽  
Nucleotide Polymorphisms ◽  
Han Population

Background. Abnormal apoptosis of keratinocytes is one of the pathological changes of psoriasis. Caspases (CASPs) are the central engines of apoptosis. Studies to date have shown that some SNPs alter the expression of related genes and lead to changes in disease risk. However, no studies have investigated the associations between gene polymorphisms and the risk of psoriasis in Han population in northeast China. Therefore, we conducted a case-control study to explore this question in Han population of northeastern China. Methods. 540 patients with PsV and 612 healthy age- and sex-matched controls were enrolled in this study. We determined the genotypes of 17 single nucleotide polymorphisms (SNPs) from 11 genes of caspase family by the improved multiplex ligation detection reaction (iMLDR) method. A model-based single SNP frequentist test and haplotype association studies were performed to evaluate the association between SNPs and PsV. Results. In the single SNP tests, rs6704688 in CASP8 was significantly associated with psoriasis vulgaris (PsV) in Han population of northeastern China (P = 0.0169, P’ = 0.0179 under the additive model; P = 0.0126, P’ = 0.0149 under the heterozygous model). In haplotype analyses, the CASP7 haplotype GC was found to be associated with PsV risk (case group versus control group, 47.2% versus 54.4%, respectively, p = 0.0149). Conclusions. Our study presented that the gene polymorphisms of CASP7 and CASP8 were significantly associated with PsV in Han population of northeastern China, which implied the functional relationship between PsV and caspase genes. CASP8 and CASP7 SNPs could be new potential biomarkers for risk stratification and prevention of PsV.

MMP-9 gene polymorphisms (rs3918242, rs3918254 and rs4810482) and the risk of psoriasis vulgaris: No evidence for associations in a Chinese Han population

2015 ◽  
Vol 168 (2) ◽  
pp. 343-348 ◽  
Author(s):  
Jingyao Liang ◽  
Tian Zhao ◽  
Juan Yang ◽  
Wei Li ◽  
Fang Zhang ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Psoriasis Vulgaris ◽  
Chinese Han Population ◽  
Chinese Han ◽  
Han Population

scholarly journals Investigation of cytokine gene polymorphisms in patients with psoriasis vulgaris

TURKDERM ◽  
2016 ◽  
Vol 50 (1) ◽  
pp. 34-38
Author(s):  
Çiğdem Kekik Çınar ◽  
Gonca Emel Karahan ◽  
Sonay Temurhan ◽  
Serpil Pirmit ◽  
Nahide Onsun ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Psoriasis Vulgaris ◽  
Cytokine Gene ◽  
Cytokine Gene Polymorphisms

IL12B gene polymorphisms have sex-specific effects in relapsing–remitting multiple sclerosis

2018 ◽  
Vol 119 (1) ◽  
pp. 83-93 ◽  
Author(s):  
Lyuba Miteva ◽  
Anastasiya Trenova ◽  
Georgi Slavov ◽  
Spaska Stanilova
Keyword(s):  
Multiple Sclerosis ◽  
Gene Polymorphisms ◽  
Specific Effects ◽  
Relapsing Remitting ◽  
Il12b Gene ◽  
Remitting Multiple Sclerosis ◽  
Relapsing Remitting Multiple Sclerosis

Three gene polymorphisms at psoriasis vulgaris

1998 ◽  
Vol 11 ◽  
pp. S293-S294
Author(s):  
V VAKDU
Keyword(s):  
Gene Polymorphisms ◽  
Psoriasis Vulgaris

scholarly journals Exploring ankylosing spondylitis-associated ERAP1, IL23R and IL12B gene polymorphisms in subphenotypes of psoriatic arthritis

Rheumatology ◽  
2012 ◽  
Vol 52 (2) ◽  
pp. 261-266 ◽  
Author(s):  
D. Jadon ◽  
W. Tillett ◽  
D. Wallis ◽  
C. Cavill ◽  
J. Bowes ◽  
...  
Keyword(s):  
Psoriatic Arthritis ◽  
Ankylosing Spondylitis ◽  
Gene Polymorphisms ◽  
Il12b Gene
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