PNPLA3 in end-stage liver disease: Alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival

2014 ◽  
Vol 29 (7) ◽  
pp. 1477-1484 ◽  
Author(s):  
Kilian Friedrich ◽  
Andreas Wannhoff ◽  
Stefan Kattner ◽  
Maik Brune ◽  
Johannes Roksund Hov ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Alcohol Consumption ◽  
Free Survival ◽  
End Stage Liver Disease ◽  
End Stage

scholarly journals Hepatorenal Syndrome: Physiology, Diagnosis and Management

2018 ◽  
Vol 35 (03) ◽  
pp. 194-197 ◽  
Author(s):  
Joseph Chmielewski ◽  
Robert Lewandowski ◽  
Haripriya Maddur
Keyword(s):  
Liver Disease ◽  
Hepatorenal Syndrome ◽  
Hepatic Dysfunction ◽  
Underlying Liver Disease ◽  
Free Survival ◽  
Renal Vasoconstriction ◽  
End Stage Liver Disease ◽  
Widespread Implementation ◽  
Intrahepatic Portosystemic Shunt ◽  
End Stage

AbstractIndividuals with end-stage liver disease are susceptible to a myriad of highly morbid complications, including hepatorenal syndrome (HRS). This specific type of renal dysfunction in patients with underlying liver disease occurs in pathophysiologically normal kidneys and is a result of renal vasoconstriction secondary to diminished renal blood flow in the setting of worsening hepatic dysfunction. Liver transplantation is curative; shortage of available organs limits access to this beneficial therapy. Medical management of HRS has demonstrated increasing promise. Transjugular intrahepatic portosystemic shunt creation has also been shown to be efficacious in enhancing transplant-free survival, although further study is advisable before widespread implementation of this strategy.

scholarly journals Data linkage to monitor hepatitis C‐associated end‐stage liver disease and hepatocellular carcinoma inpatient stays in England

2019 ◽  
Vol 27 (1) ◽  
pp. 20-27
Author(s):  
Georgina Ireland ◽  
Ruth Simmons ◽  
Matthew Hickman ◽  
Ross Harris ◽  
Mary Ramsay ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Hepatitis C ◽  
Data Linkage ◽  
End Stage Liver Disease ◽  
End Stage
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