End‐stage heart failure patient, care provider, and climate change‐driven natural disaster

Author(s):  
Rujittika Mungmunpuntipantip ◽  
Viroj Wiwanitkit
2018 ◽  
Vol 6 ◽  
pp. 2050313X1878921
Author(s):  
Vera Hergesell ◽  
Erwin Mathew ◽  
Peter Kornprat ◽  
Igor Knez ◽  
Hans-Joerg Mischinger ◽  
...  

Management of end-stage heart failure patients requiring major general surgery is not well defined. Due to poor cardiorespiratory reserve, perioperative morbidity and mortality are excessively high. We report a case of temporary implementation of veno-arterial extracorporeal membrane oxygenation for haemodynamic support during excision of rectal carcinoma in an end-stage heart failure patient and describe perioperative management.


Author(s):  
Ahmed Alnajar ◽  
O. H. "Bud" Frazier ◽  
Abdelmotagaly Elgalad ◽  
P. Alex Smith ◽  
James M. Shultz

Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).


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