Concomitant Repair For Mild Aortic Insufficiency And Implantation Of Left Ventricle Mechanical Support

Aortic valve regurgitation in patients undergoing LVAD implantation is a significant complication which occurs in up to 10% of patients in the INTERMACS database. Patients who have aortic valve regurgitation at the time of implant have been handled by several methods, including aortic valve leaflets approximation, to aortic valve replacement or even valve closure. We report a case where we used HAART Ring to repair a regurgitant aortic valve during LAVD implant for destination therapy.

Role of yoga prana vidya healing techniques in successful and speedy recovery of orthopaedic cases of bone injuries and fractures: a multiple case study

<p class="abstract">Bones form a vital part of the skeletal system providing mechanical support, strength, structure and protection to the human body. Inability of the bone to resist any kind of stress caused accidently can result in a bone injury or a fracture. This article provides a summary of eleven cases of bone injury and fracture treated successfully by yoga prana vidya (YPV) techniques as a complementary medicine for faster recovery. The study was carried out by two healers who independently healed eleven cases of bone injury and fracture using the bone regeneration techniques of YPV. Further, the data was collected and the results were analysed. By application of YPV healing techniques complementarily, it is observed that full recovery took place within 10 days to 45 days for the 3 hospitalised cases, and within 3 to 8 days for the two patients who had bandage/dressing done at a medical facility. In case of the remaining 6 patients who sought YPV healing help in preference to seeking medical help the recovery took place within 5 to 20 days. helping the patients to lead a normal life thereafter. It is observed that YPV techniques can be used for faster recovery of patients with injured and fractured bones. This paper shows the successful results when the techniques were applied on eleven participants. It is recommended to conduct further studies on a larger scale for the healing of bone related cases such as injury and fractures.</p>

Case Report: Fulminant Myocarditis Successfully Treated With Extracorporeal Membrane Oxygenation in Ikeda Strain Orientia tsutsugamushi Infection

Scrub typhus is an acute zoonotic febrile illness caused by Orientia tsutsugamushi having a specific geographic endemic area. This infection could be complicated with multi-organ involvement including myocarditis with variable severity. Here, we report a rare case of scrub typhus with biopsy-proven acute fulminant myocarditis which progressed very rapidly to cardiac arrest and was treated successfully with extracorporeal cardiopulmonary resuscitation. Clinicians should be alert to possible rapid progression of scrub typhus myocarditis to fulminant form and be prepared for close monitoring and temporary mechanical support if indicated.

Status of the WEST Travelling Wave Array antenna design and results from the high power mock-up

A mock-up of the WEST TWA antenna was designed in 2019, manufactured during 2020 and installed in the TITAN test facility in the beginning of 2021. The paper presents the current status of the WEST TWA antenna, its mock-up and a possible extrapolation to DEMO. The updated WEST TWA design has a reduced antenna length and features feeding and mechanical support from a single vessel port. The first results of the mock-up at low power, its diagnostic system and the prospects are explained. Extensions versus a TWA antenna for WEST, and a possible DEMO TWA system are briefly discussed.

Anthracyclines in a patient with acute leukemia and severe cardiomyopathy requiring mechanical support: A case report

Introduction For young adult patients with acute leukemia, both the efficacy and cardiotoxicity of anthracycline-based regimens have been documented. We report the case of a patient with severe cardiomyopathy, mechanically supported by a left ventricular assist device (LVAD), who subsequently developed Philadelphia-chromosome positive acute lymphoblastic leukemia (Ph + ALL). To our knowledge, this is the first report of anthracycline administration in a patient with heart failure requiring mechanical support. Case report Our 27-year-old female patient was diagnosed with Ph + B-ALL as part of workup for leukocytosis. Past medical history included non-ischemic cardiomyopathy with a left ventricular ejection fraction of 30–35% and moderate-severe right ventricular dysfunction, for which LVAD had been placed 4 years previously. Management & outcome After shared decision-making and multidisciplinary discussions, we felt that hyperfractionated cyclophosphamide, doxorubicin, vincristine, and dexamethasone alternating with cytarabine and high-dose methotrexate in addition to ponatinib (HyperCVAD-ponatinib) best balanced the patient's goals for aggressive treatment with the potential for rapid and durable remissions. The patient received a single reduced dose of doxorubicin alongside dexrazoxane with her first cycle of HyperCVAD-ponatinib. She attained a complete molecular response 22 days later and remains in remission (with stable cardiac function) 30 months later on maintenance therapy. Discussion In conclusion, LVAD placement is not an absolute contra-indication to anthracyclines if such therapies offer the best opportunity for a durable response.