Sclerosingangiomatoid nodular transformation of spleen in a pediatric malignancy patient

2021 ◽  
Author(s):  
Hee‐Jeong Lim ◽  
Youngeun Yoo ◽  
SunHee Sung ◽  
Eun Sun Yoo
Keyword(s):  
Pediatric Malignancy

1132 G-CSF mobilization effect on PSC in pediatric malignancy

1995 ◽  
Vol 31 ◽  
pp. S237
Author(s):  
M. Ohira ◽  
J. Takayama ◽  
Y. Kuroda ◽  
Y. Takaue ◽  
K. Kawano ◽  
...  
Keyword(s):  
Pediatric Malignancy

Chronic Myelogenous Leukemia Presenting as a Secondary Malignancy After BCR-ABL1-negative B-lymphoblastic Leukemia/Lymphoma in a Pediatric Patient

2017 ◽  
Vol 20 (1) ◽  
pp. 58-62
Author(s):  
Gheorghe Popa ◽  
Cristina Blag ◽  
Horatiu Olteanu
Keyword(s):  
Complete Remission ◽  
Pediatric Patient ◽  
Chronic Myelogenous Leukemia ◽  
Pediatric Population ◽  
Lymphoblastic Leukemia ◽  
Myeloproliferative Neoplasm ◽  
Myelogenous Leukemia ◽  
Secondary Malignancy ◽  
Pediatric Malignancy ◽  
Pathologic Features

Chronic myelogenous leukemia, BCR-ABL1 positive (CML) is a rare myeloproliferative neoplasm in children and presents even less often as a secondary malignancy in the pediatric population. Below, we report a patient with Philadelphia-negative B-lymphoblastic leukemia/lymphoma, who developed CML several years after achieving complete remission, and summarize the existing literature on the clinical and pathologic features of CML as a secondary pediatric malignancy.

Percutaneous Image-Guided Treatment of Pediatric Malignancy

2013 ◽  
pp. 923-932
Author(s):  
William E. Shiels ◽  
Mark J. Hogan
Keyword(s):  
Pediatric Malignancy ◽  
Image Guided

Thrombosis in pediatric malignancy

2018 ◽  
Vol 29 (7) ◽  
pp. 596-601 ◽  
Author(s):  
Mohammadreza Bordbar ◽  
Mehran Karimi ◽  
Nader Shakibazad
Keyword(s):  
Pediatric Malignancy

Pediatric Malignancy

2021 ◽  
pp. 236-277
Keyword(s):  
Pediatric Malignancy

scholarly journals Chronic Hepatitis C Virus Infection After Treatment for Pediatric Malignancy

Blood ◽  
1997 ◽  
Vol 90 (3) ◽  
pp. 1315-1320 ◽  
Author(s):  
Simone Cesaro ◽  
Maria Grazia Petris ◽  
Flavio Rossetti ◽  
Riccardo Cusinato ◽  
Corrado Pipan ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Virus Infection ◽  
Chronic Liver Disease ◽  
Chronic Liver ◽  
Hcv Infection ◽  
Pediatric Malignancy ◽  
Infection Markers

Abstract Sera of 658 patients who had completed treatment for pediatric malignancy were analyzed by a second-generation enzyme-linked immunosorbent assay and recombinant immunoblot assay test to assess the prevalence of hepatitis C virus (HCV)-seropositivity. All HCV-seropositive patients underwent detailed clinical, laboratory, virologic, and histologic study to analyze the course of HCV infection. One hundred seventeen of the 658 patients (17.8%) were positive for HCV infection markers. Among the 117 anti-HCV+ patients, 41 (35%) were also positive for markers of hepatitis B virus infection with or without delta virus infection markers, 91 (77.8%) had previously received blood product transfusions, and 25 (21.4%) showed a normal alanine aminotransferase (ALT) level during the last 5-year follow-up (11 of them never had abnormal ALT levels). The remaining 92 patients showed ALT levels higher than the upper limit of normal range. Eighty-one of 117 (70%) anti-HCV+ patients were HCV-RNA+, with genotype 1b being present in most patients (54%). In univariate analysis, no risk factor for chronic liver disease was statistically significant. In this study, the prevalence of HCV infection was high in patients who were treated for a childhood malignancy. In about 20% of anti-HCV+ patients, routes other than blood transfusions are to be considered in the epidemiology of HCV infection. After a 14-year median follow-up, chronic liver disease of anti-HCV+ positive patients did not show progression to liver failure.

IL-2 Adenovector-Transduced Autologous Tumor Cells Induce Antitumor Immune Responses in Patients With Neuroblastoma

Blood ◽  
1998 ◽  
Vol 92 (6) ◽  
pp. 1941-1949 ◽  
Author(s):  
Laura Bowman ◽  
Michael Grossmann ◽  
Donna Rill ◽  
Michael Brown ◽  
Wan-yun Zhong ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Cytotoxic T Cell ◽  
Autologous Tumor ◽  
Murine Models ◽  
Dose Escalation Study ◽  
Local Inflammatory Response ◽  
Pediatric Malignancy ◽  
American Society ◽  
Complete Tumor ◽  
Antitumor Antibody

Abstract In many different murine models, the immunogenicity of tumor cells can be increased by transduction with a range of immunostimulatory genes, inducing an immune response that causes regression of pre-existing unmodified tumor cells. To investigate the relevance of these animal models to pediatric malignancy, we used autologous unirradiated tumor cells transduced with an adenovirus-IL-2 to immunize 10 children with advanced neuroblastoma. In a dose-escalation study, we found that this tumor immunogen induced a moderate local inflammatory response consisting predominantly of CD4+ T lymphocytes, and a systemic response, with a rise in circulating CD25+and DR+ CD3+ T cells. Patients also made a specific antitumor response, manifest by an IgG antitumor antibody and increased cytotoxic T-cell killing of autologous tumor cells. Clinically, five patients had tumor responses after the tumor immunogen alone (one complete tumor response, one partial response, and three with stable disease). Four of these five patients were shown to have coexisting antitumor cytotoxic activity, as opposed to only one of the patients with nonresponsive disease. These results show a promising correlation between preclinical observations and clinical outcome in this disease, and support further exploration of the approach for malignant diseases of children. © 1998 by The American Society of Hematology.

The Graft-Versus-Tumor Effect in Pediatric Malignancy

2010 ◽  
Vol 57 (1) ◽  
pp. 67-81 ◽  
Author(s):  
Terry J. Fry ◽  
Andre Willasch ◽  
Peter Bader
Keyword(s):  
Pediatric Malignancy ◽  
Graft Versus Tumor Effect

scholarly journals High rate of TTV infection in multitransfused patients with pediatric malignancy and hematological disorders

2000 ◽  
Vol 65 (1) ◽  
pp. 41-44 ◽  
Author(s):  
Miho Maeda ◽  
Hisamitsu Hamada ◽  
Akio Tsuda ◽  
Kiyoshi Kaneko ◽  
Yoshitaka Fukunaga
Keyword(s):  
High Rate ◽  
Pediatric Malignancy ◽  
Hematological Disorders

Undernutrition in Pediatric Malignancy

2017 ◽  
Vol 84 (11) ◽  
pp. 875-876
Author(s):  
Anirban Das ◽  
Reshma Ray ◽  
Tiash Sinha ◽  
Manash Gogoi ◽  
Shekhar Krishnan ◽  
...  
Keyword(s):  
Pediatric Malignancy
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