Urinary Cyclophilin A and serum Cystatin C as biomarkers for diabetic nephropathy in children with type 1 diabetes

2020 ◽  
Vol 21 (5) ◽  
pp. 846-855 ◽  
Author(s):  
Nanees Abdel‐Badie Salem ◽  
Rania Mostafa El Helaly ◽  
Ibrahim Maroof Ali ◽  
Hala Abd Alem Ebrahim ◽  
Mostafa Mahmoud Alayooti ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Diabetic Nephropathy ◽  
Cystatin C ◽  
Cyclophilin A ◽  
Serum Cystatin C ◽  
Serum Cystatin

Author response for "Urinary Cyclophilin A and Serum Cystatin C as Biomarkers for Diabetic Nephropathy in Children with Type 1 Diabetes"

2020 ◽  
Author(s):  
Nanees Abdel‐Badie Salem ◽  
Rania Mostafa El Helaly ◽  
Ibrahim Maroof Ali ◽  
Hala Abd Alem Ebrahim ◽  
Mostafa Mahmoud Alayooti ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Diabetic Nephropathy ◽  
Cystatin C ◽  
Cyclophilin A ◽  
Author Response ◽  
Serum Cystatin C ◽  
Serum Cystatin

scholarly journals Serum Cystatin C and the Incidence of Hypertension in Type 1 Diabetes Mellitus

2011 ◽  
Vol 24 (1) ◽  
pp. 59-63 ◽  
Author(s):  
K. Sahakyan ◽  
B. E. K. Klein ◽  
K. E. Lee ◽  
M. Y. Tsai ◽  
R. Klein
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Cystatin C ◽  
Serum Cystatin C ◽  
Serum Cystatin

scholarly journals Serum Cystatin C as a Biomarker for Early Diabetic Nephropathy and Dyslipidemia in Young Type 1 Diabetes Patients

2020 ◽  
Author(s):  
Lina Radzeviciene ◽  
Ingrida Stankute ◽  
Ausra Monstaviciene ◽  
Rimantė Dobrovolskiene ◽  
Evalda Danyte ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Kidney Function ◽  
Cystatin C ◽  
Young Patients ◽  
Kidney Injury ◽  
Albumin Excretion Rate ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Long Term Follow Up

Abstract Background. Early capture of initial stages of complications is the destination of long term follow up of type 1 diabetes (T1D) patients. The aim of this study was to assess the clinical significance of serum cystatin C in the early diagnosis of renal injury and its association with dyslipidemia in young T1D patients.Methods. 779 subjects were evaluated for kidney function by estimating glomerular filtration rate (eGFR) based on serum creatinine (eGFRcreat) and cystatin C (eGFRcys). Results. Median age of study subjects was 16.2 years (2.1;26.4), diabetes duration – 5.3 years (0.51;24.0). The median of HbA1c was 8% (5.2;19.9) (64 mmol/mol (33.3;194)); 24.2% of participants had HbA1c <7% (53 mmol/mol). Elevated albumin excretion rate was found in 13.5% of subjects. The median of cystatin C was 0.8 mg/L (0.33;1.71), the median of creatinine – 63 µmol/L (6;126). Median of eGFRcys was lower than eGFRcreat (92 ml/min/1.73m2 vs. 101 ml/min/1.73m2, p<0.001). 30.2% of all patients were classified as having worse kidney function when using cystatin C vs. creatinine for eGFR calculation. Linear correlations were found between cystatin C and HbA1c, r=-0.088, p<0.05, as well as cystatin C and HDL, r=-0.097, p<0.01.Conclusion. This study showed that cystatin C might be used as an additional biomarker of early kidney injury for young patients with T1D.

Serum cystatin C levels are decreased in type 1 diabetes mellitus patients with diabetic ketoacidosis

2020 ◽  
Vol 45 (2) ◽  
Author(s):  
Yiping Cheng ◽  
Chao Xu ◽  
Sichao Wang ◽  
Lin Hou ◽  
Qingbo Guan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Diabetic Ketoacidosis ◽  
Cystatin C ◽  
Serum Cystatin C ◽  
Serum Cystatin

Does serum cystatin C level reflect insulin resistance in patients with type 1 diabetes?

2014 ◽  
Vol 47 (13-14) ◽  
pp. 1235-1238 ◽  
Author(s):  
A. Uruska ◽  
A. Araszkiewicz ◽  
D. Zozulinska-Ziolkiewicz ◽  
M. Wegner ◽  
A. Grzelka ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Type 1 Diabetes ◽  
Cystatin C ◽  
Serum Cystatin C ◽  
Serum Cystatin
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