Epidermal Langerhans cells resistance to solar‐simulated radiation in actinic prurigo patients with low minimal erythema dose

2019 ◽  
Vol 36 (2) ◽  
pp. 105-110
Author(s):  
Martha Cecilia Valbuena ◽  
Mariam Rolon Cadena
Keyword(s):  
Langerhans Cells ◽  
Minimal Erythema Dose ◽  
Actinic Prurigo ◽  
Epidermal Langerhans Cells

Epidermal Langerhans cells in actinic prurigo: a comparison between lesional and non-lesional skin

2009 ◽  
Vol 23 (11) ◽  
pp. 1348-1348
Author(s):  
B Torres-Álvarez ◽  
JP Castanedo-Cázares ◽  
B Moncada
Keyword(s):  
Langerhans Cells ◽  
Lesional Skin ◽  
Actinic Prurigo ◽  
Epidermal Langerhans Cells

Epidermal Langerhans cells in actinic prurigo: a comparison between lesional and non-lesional skin

2009 ◽  
Vol 23 (11) ◽  
pp. 1349-1349
Author(s):  
J Calderón-Amador ◽  
A Flores-Langarica ◽  
A Silva-Sánchez ◽  
L Donis-Maturano ◽  
J Granados ◽  
...  
Keyword(s):  
Langerhans Cells ◽  
Lesional Skin ◽  
Actinic Prurigo ◽  
Epidermal Langerhans Cells

Epidermal Langerhans cells in actinic prurigo: a comparison between lesional and non-lesional skin

2009 ◽  
Vol 23 (4) ◽  
pp. 438-440 ◽  
Author(s):  
J Calderón-Amador ◽  
A Flores-Langarica ◽  
A Silva-Sánchez ◽  
L Donis-Maturano ◽  
J Granados ◽  
...  
Keyword(s):  
Langerhans Cells ◽  
Lesional Skin ◽  
Actinic Prurigo ◽  
Epidermal Langerhans Cells

In vitro primary sensitization of hapten-specific T cells by cultured human epidermal Langerhans cells - a screening predictive assay for contact sensitizers

1996 ◽  
Vol 26 (5) ◽  
pp. 563-570 ◽  
Author(s):  
M. KRASTEVA ◽  
J. PEGUET-NAVARRO ◽  
C. MOULON ◽  
P. COURTELLEMONT ◽  
G. REDZINIAK ◽  
...  
Keyword(s):  
T Cells ◽  
Langerhans Cells ◽  
Primary Sensitization ◽  
Predictive Assay ◽  
Epidermal Langerhans Cells

scholarly journals Morphological Alterations and Increased S100B Expression in Epidermal Langerhans Cells Detected in Skin from Patients with Progressive Vitiligo

Life ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 579
Author(s):  
Fei Yang ◽  
Lingli Yang ◽  
Lanting Teng ◽  
Huimin Zhang ◽  
Ichiro Katayama
Keyword(s):  
Electron Microscopy ◽  
Langerhans Cells ◽  
Critical Role ◽  
Light And Electron Microscopy ◽  
Morphological Alterations ◽  
Birbeck Granules ◽  
Immuno Electron Microscopy ◽  
Skin Biopsies ◽  
Epidermal Langerhans Cells

The role of Langerhans cells (LCs) in vitiligo pathogenesis remains unclear, with published studies reporting contradictory results regarding the quantity of LCs and no data on the features of LCs in vitiligo. Here, we aimed to analyze the presence, density, and morphological features of LCs in the epidermis of patients with vitiligo. Skin biopsies were stained for LCs using anti-CD1a/anti-langerin antibodies and analyzed by immunocytochemistry with light and electron microscopy. Compared with healthy controls, we detected significantly increased numbers of epidermal LCs in lesional skin from vitiligo in the progressive state. These LCs exhibited striking morphological alterations, including an elevated number of dendrites, with increased length and more branches than dendrites from controls. Ultrastructure examination via immuno-electron microscopy revealed markedly reduced Birbeck granules (BGs) and shorter BG rods in LCs from progressive vitiligo, with higher expression of langerin. Additionally, expression of S100B, the activity biomarker of vitiligo, was increased in these LCs. This work provides new insight on the cellular composition of LCs in vitiliginous skin, revealing altered morphology and increased LC numbers, with elevated S100B expression. Our data suggest LCs might play a critical role in vitiligo pathogenesis and thus may represent a novel therapeutic target for this disease.

Canine Epidermal Langerhans Cells Express α and γ but not β Chains of High-Affinity IgE Receptor

2005 ◽  
Vol 29 (6) ◽  
pp. 499-505 ◽  
Author(s):  
M. Bonkobara ◽  
F. Miyake ◽  
H. Yagihara ◽  
O. Yamada ◽  
D. Azakami ◽  
...  
Keyword(s):  
Langerhans Cells ◽  
Ige Receptor ◽  
High Affinity ◽  
High Affinity Ige Receptor ◽  
Epidermal Langerhans Cells

scholarly journals Cell-Specific Gene Expression in Langerhans Cell Histiocytosis Lesions Reveals a Distinct Profile Compared with Epidermal Langerhans Cells

2010 ◽  
Vol 184 (8) ◽  
pp. 4557-4567 ◽  
Author(s):  
Carl E. Allen ◽  
Liunan Li ◽  
Tricia L. Peters ◽  
Hon-chiu Eastwood Leung ◽  
Alexander Yu ◽  
...  
Keyword(s):  
Gene Expression ◽  
Langerhans Cells ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Specific Gene ◽  
Specific Gene Expression ◽  
Epidermal Langerhans Cells

A COMPARATIVE STUDY OF THE FUNCTIONS OF EPIDERMAL LANGERHANS CELLS IN HAIRLESS MICE AND NUDE MICE

1980 ◽  
Vol 7 (2) ◽  
pp. 101-108
Author(s):  
Mamoru Masutani ◽  
Kunio Iwahara
Keyword(s):  
Comparative Study ◽  
Nude Mice ◽  
Langerhans Cells ◽  
Hairless Mice ◽  
Epidermal Langerhans Cells
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