scholarly journals Eligibility for anti‐fibrotic treatment in idiopathic pulmonary fibrosis depends on the predictive equation used for pulmonary function testing

Respirology ◽  
2019 ◽  
Vol 24 (10) ◽  
pp. 988-995 ◽  
Author(s):  
Andrew Burgess ◽  
Ken Goon ◽  
John D. Brannan ◽  
John Attia ◽  
Kerrin Palazzi ◽  
...  
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Pulmonary Function ◽  
Pulmonary Function Testing ◽  
Predictive Equation ◽  
Function Testing

Pulmonary Hypertension and Pulmonary Function Testing in Idiopathic Pulmonary Fibrosis

CHEST Journal ◽  
2007 ◽  
Vol 131 (3) ◽  
pp. 657-663 ◽  
Author(s):  
Steven D. Nathan ◽  
Oksana A. Shlobin ◽  
Shahzad Ahmad ◽  
Susan Urbanek ◽  
Scott D. Barnett
Keyword(s):  
Pulmonary Hypertension ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Pulmonary Function ◽  
Pulmonary Function Testing ◽  
Function Testing

scholarly journals Combined Pulmonary Fibrosis and Emphysema: Pulmonary Function Testing and a Pathophysiology Perspective

Medicina ◽  
2019 ◽  
Vol 55 (9) ◽  
pp. 580
Author(s):  
Diana E. Amariei ◽  
Neal Dodia ◽  
Janaki Deepak ◽  
Stella E. Hines ◽  
Jeffrey R. Galvin ◽  
...  
Keyword(s):  
Gas Exchange ◽  
Pulmonary Fibrosis ◽  
Pulmonary Function ◽  
Lung Volume ◽  
Pulmonary Emphysema ◽  
Imaging Modality ◽  
Lung Compliance ◽  
Ct Imaging ◽  
Pulmonary Function Testing ◽  
Function Testing

Combined pulmonary fibrosis and emphysema (CPFE) has been increasingly recognized over the past 10–15 years as a clinical entity characterized by rather severe imaging and gas exchange abnormalities, but often only mild impairment in spirometric and lung volume indices. In this review, we explore the gas exchange and mechanical pathophysiologic abnormalities of pulmonary emphysema, pulmonary fibrosis, and combined emphysema and fibrosis with the goal of understanding how individual pathophysiologic observations in emphysema and fibrosis alone may impact clinical observations on pulmonary function testing (PFT) patterns in patients with CPFE. Lung elastance and lung compliance in patients with CPFE are likely intermediate between those of patients with emphysema and fibrosis alone, suggesting a counter-balancing effect of each individual process. The outcome of combined emphysema and fibrosis results in higher lung volumes overall on PFTs compared to patients with pulmonary fibrosis alone, and the forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) ratio in CPFE patients is generally preserved despite the presence of emphysema on chest computed tomography (CT) imaging. Conversely, there appears to be an additive deleterious effect on gas exchange properties of the lungs, reflecting a loss of normally functioning alveolar capillary units and effective surface area available for gas exchange, and manifested by a uniformly observed severe reduction in the diffusing capacity for carbon monoxide (DLCO). Despite normal or only mildly impaired spirometric and lung volume indices, patients with CPFE are often severely functionally impaired with an overall rather poor prognosis. As chest CT imaging continues to be a frequent imaging modality in patients with cardiopulmonary disease, we expect that patients with a combination of pulmonary emphysema and pulmonary fibrosis will continue to be observed. Understanding the pathophysiology of this combined process and the abnormalities that manifest on PFT testing will likely be helpful to clinicians involved with the care of patients with CPFE.

Specifications for equipment used for infant pulmonary function testing

2000 ◽  
Vol 16 (4) ◽  
pp. 731 ◽  
Author(s):  
U. Frey ◽  
J. Stocks ◽  
A Coates ◽  
P Sly ◽  
J Bates ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Pulmonary Function Testing ◽  
Function Testing ◽  
Infant Pulmonary Function ◽  
Infant Pulmonary Function Testing

scholarly journals Pulmonary Function Testing in Work-Related Asthma: An Overview from Spirometry to Specific Inhalation Challenge

2021 ◽  
Vol 18 (5) ◽  
pp. 2325
Author(s):  
Mathias Poussel ◽  
Isabelle Thaon ◽  
Emmanuelle Penven ◽  
Angelica I. Tiotiu
Keyword(s):  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Objective Evaluation ◽  
Pulmonary Function Testing ◽  
Initial Assessment ◽  
Work Related ◽  
Specific Inhalation Challenge ◽  
Occupational Setting ◽  
Inhalation Challenge ◽  
Function Testing

Work-related asthma (WRA) is a very frequent condition in the occupational setting, and refers either to asthma induced (occupational asthma, OA) or worsened (work-exacerbated asthma, WEA) by exposure to allergens (or other sensitizing agents) or to irritant agents at work. Diagnosis of WRA is frequently missed and should take into account clinical features and objective evaluation of lung function. The aim of this overview on pulmonary function testing in the field of WRA is to summarize the different available tests that should be considered in order to accurately diagnose WRA. When WRA is suspected, initial assessment should be carried out with spirometry and bronchodilator responsiveness testing coupled with first-step bronchial provocation testing to assess non-specific bronchial hyper-responsiveness (NSBHR). Further investigations should then refer to specialists with specific functional respiratory tests aiming to consolidate WRA diagnosis and helping to differentiate OA from WEA. Serial peak expiratory flow (PEF) with calculation of the occupation asthma system (OASYS) score as well as serial NSBHR challenge during the working period compared to the off work period are highly informative in the management of WRA. Finally, specific inhalation challenge (SIC) is considered as the reference standard and represents the best way to confirm the specific cause of WRA. Overall, clinicians should be aware that all pulmonary function tests should be standardized in accordance with current guidelines.

Pulmonary Function Testing in Patients with Tracheostomies: Feasibility and Technical Considerations

Lung ◽  
2021 ◽  
Author(s):  
Ajay Sheshadri ◽  
Leendert Keus ◽  
David Blanco ◽  
Xiudong Lei ◽  
Cheryl Kellner ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Pulmonary Function Testing ◽  
Function Testing ◽  
Technical Considerations
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