scholarly journals A multicenter, randomized, single‐blind trial comparing the efficacy of viable cryopreserved placental membrane to human fibroblast‐derived dermal substitute for the treatment of chronic diabetic foot ulcers

2018 ◽  
Vol 26 (3) ◽  
pp. 274-283 ◽  
Author(s):  
Charles E. Ananian ◽  
Yadwinder S. Dhillon ◽  
Carl C. Van Gils ◽  
D. Craig Lindsey ◽  
Raymond J. Otto ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Human Fibroblast ◽  
Foot Ulcers ◽  
Dermal Substitute ◽  
Diabetic Foot Ulcers ◽  
Blind Trial ◽  
Single Blind ◽  
Single Blind Trial

scholarly journals Comparative effectiveness of a human fibroblast-derived dermal substitute and a viable cryopreserved placental membrane for the treatment of diabetic foot ulcers

2019 ◽  
Vol 8 (14) ◽  
pp. 1229-1238
Author(s):  
Michael L Sabolinski ◽  
John V Capotorto
Keyword(s):  
Confidence Interval ◽  
Diabetic Foot ◽  
Human Fibroblast ◽  
Comparative Effectiveness ◽  
Wound Closure ◽  
Foot Ulcers ◽  
Dermal Substitute ◽  
Diabetic Foot Ulcers ◽  
Electronic Medical Record Database ◽  
Medical Record Database

Objective: To compare a human fibroblast-derived dermal substitute (HFDS) to a viable cryopreserved placental membrane (vCPM) for use in diabetic foot ulcers (DFUs). Methods: An electronic medical record database of 1622 refractory DFUs with areas 1–40 cm2 was analyzed. Results: Cox estimates of wound closure for HFDS (1444 wounds) were significantly greater (p = 0.0002) by weeks 12 (31 vs 21%), 24 (55 vs 39%) and 36 (68 vs 51%) compared with vCPM (178 wounds). HFDS reduced the median time to wound closure by 55% compared with vCPM, (20 vs 36 weeks, p = 0.0002). HFDS also increased the probability of wound closure by 60% (hazard ratio = 1.60 [95% confidence interval, (1.25, 2.06)], p = 0.0002). Conclusion: HFDS improved time and frequency of wound closure in DFUs versus vCPM.

Dermal Substitute Template Use in Diabetic Foot Ulcers

2012 ◽  
Vol 11 (3) ◽  
pp. 161-164 ◽  
Author(s):  
Swethan Alagaratnam ◽  
Andrew Choong ◽  
Alexander Loh
Keyword(s):  
Diabetic Foot ◽  
Foot Ulcers ◽  
Dermal Substitute ◽  
Diabetic Foot Ulcers

Randomized Prospective Double-Blind Trial in Healing Chronic Diabetic Foot Ulcers: CT-102 activated platelet supernatant, topical versus placebo

Diabetes Care ◽  
1992 ◽  
Vol 15 (11) ◽  
pp. 1598-1604 ◽  
Author(s):  
D. L. Steed ◽  
J. B. Goslen ◽  
G. A. Holloway ◽  
J. M. Malone ◽  
T. J. Bunt ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial

Abstract #295 Epidemiologic and Clinical Characteristics of Diabetic Foot Ulcers – Report From South West Nigeria

2019 ◽  
Vol 25 ◽  
pp. 121-122
Author(s):  
Olufunmilayo Adeleye ◽  
Ejiofor Ugwu ◽  
Anthonia Ogbera ◽  
Akinola Dada ◽  
Ibrahim Gezawa ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Clinical Characteristics ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
South West
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