scholarly journals The inspired sine-wave technique: A novel method to measure lung volume and ventilatory heterogeneity

2018 ◽  
Vol 103 (5) ◽  
pp. 738-747 ◽  
Author(s):  
Richard M. Bruce ◽  
Phi Anh Phan ◽  
Edmund Pacpaco ◽  
Najib M. Rahman ◽  
Andrew D. Farmery
Author(s):  
Ajay Kumar Dabas ◽  
Vikram Patra ◽  
Sebasish Metia ◽  
D Mahapatra ◽  
Vijoy Kumar Jha ◽  
...  

Author(s):  
Shehan Jayasekera ◽  
Edward Hensel ◽  
Risa Robinson

Background: Limited research has been done to measure ambulatory respiratory behavior, in particular those associated with tobacco use, in the natural environment due to a lack of monitoring techniques. Respiratory topography parameters provide useful information for modeling particle deposition in the lung and assessing exposure risk and health effects associated with tobacco use. Commercially available Wearable Respiratory Monitors (WRM), such as the Hexoskin Smart Garment, have embedded sensors that measure chest motion and may be adapted for measuring ambulatory lung volume. Methods: Self-reported “everyday” and “some days” Hookah and Cigarette smokers were recruited for a 3-day natural environment observation study. Participants wore the Hexoskin shirt while using their preferred tobacco product. The shirt was calibrated on them prior to, during, and after the observation period. A novel method for calculating the calibration parameters is presented. Results: NH = 5 Hookah and NC = 3 Cigarette participants were enrolled. Calibration parameters were obtained and applied to the observed chest motion waveform from each participant to obtain their lung volume waveform. Respiratory topography parameters were derived from the lung volume waveform. Conclusion: The feasibility of using the Hexoskin for measuring ambulatory respiratory topography parameters in the natural environment is demonstrated.


Author(s):  
Shehan Jayasekera ◽  
Edward Hensel ◽  
Risa Robinson

Background: Limited research has been done to measure ambulatory respiratory behavior, in particular those associated with tobacco use, in the natural environment due to a lack of monitoring techniques. Respiratory topography parameters provide useful information for modelling particle deposition in the lung and assessing exposure risk and health effects associated with tobacco use. Commercially available Wearable Respiratory Monitors (WRM), such as the Hexoskin Smart Garment, have embedded sensors which measure chest motion and may be adapted for measuring ambulatory lung volume. Methods: Self-reported ‘everyday’ and ‘some days’ Hookah and Cigarette smokers were recruited for a 3-day natural environment observation study. Participants wore the Hexoskin shirt while using their preferred tobacco product. The shirt was calibrated on them prior to, during, and after the observation period. A novel method for calculating the calibration parameters is presented. Results: N=5 Hookah and N=3 Cigarette participants were enrolled. Calibration parameters were obtained and applied to the observed chest motion waveform from each participant to obtain their lung volume waveform. Respiratory topography parameters were derived from the lung volume waveform. Conclusion: The feasibility of using the Hexoskin for measuring ambulatory respiratory topography parameters in the natural environment is demonstrated..


Author(s):  
Ryan Amelon ◽  
Kunlin Cao ◽  
Kai Ding ◽  
Gary E. Christensen ◽  
Joseph M. Reinhardt ◽  
...  

Regional lung deformation (as opposed to whole lung volume change) may be an indicator of localized lung malformations. Regional deformation may be characterized by principal strains, but lack a direct physiological relevance. Alternatively, regional volume change (distribution of Jacobian) is physiologically intuitive, but does not characterize all aspects of deformation. For instance, a region may undergo no volume change, but still have deformed significantly — say, when the lengthening in one direction is compensated by contraction along another direction. From a perspective of physiological relevance to lung function, lung deformation may be thought to encompass both the volume change and directional preferences in volume change.


Author(s):  
M.A. Gregory ◽  
G.P. Hadley

The insertion of implanted venous access systems for children undergoing prolonged courses of chemotherapy has become a common procedure in pediatric surgical oncology. While not permanently implanted, the devices are expected to remain functional until cure of the primary disease is assured. Despite careful patient selection and standardised insertion and access techniques, some devices fail. The most commonly encountered problems are colonisation of the device with bacteria and catheter occlusion. Both of these difficulties relate to the development of a biofilm within the port and catheter. The morphology and evolution of biofilms in indwelling vascular catheters is the subject of ongoing investigation. To date, however, such investigations have been confined to the examination of fragments of biofilm scraped or sonicated from sections of catheter. This report describes a novel method for the extraction of intact biofilms from indwelling catheters.15 children with Wilm’s tumour and who had received venous implants were studied. Catheters were removed because of infection (n=6) or electively at the end of chemotherapy.


Author(s):  
Brenda E. Lambert ◽  
Ernest C. Hammond

The purpose of this study was to examine the external structure of four human hair shaft samples with the scanning Electron Microscope (SEM) and to obtain information regarding the chemical composition of hair by using the attached x ray microanalysis unit.The hair samples were obtained from two female subjects. Sample A was taken from a black female and had not undergone any type of chemical processing. Sample B, C, D were taken from a white female, and were natural, processed, and unpigmented, i.e. “gray”, respectively. Sample C had been bleached, tinted, and chemically altered using a permanent wave technique.


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