Growth and Dissolution of Encapsulated Microbubble Used in Ultrasound Contrast Imaging

2006 ◽  
Author(s):  
Pankaj Jain ◽  
Kausik Sarkar

Steady dissolution of a bubble with two gases and a permeable shell has been modeled. At first the shell is modeled without elasticity. Factors such as permeability of the shell, surface tension, mole fraction of the osmotic agent, gas concentration in the bulk have been varied to study the growth and the time scale for dissolution of the bubble. It has been found that the inclusion of shell elasticity also plays a vital role in the growth and dissolution of the bubble.

2009 ◽  
Vol 27 (2) ◽  
pp. 14-24 ◽  
Author(s):  
Jeff Powers ◽  
Michalakis Averkiou ◽  
Matthew Bruce

2006 ◽  
pp. 309-316
Author(s):  
F. Forsberg ◽  
M. T. Ismail ◽  
E. K. Hagen ◽  
D. A. Merton ◽  
J. B. Liu ◽  
...  

2005 ◽  
Vol 27 (2) ◽  
pp. 65-74 ◽  
Author(s):  
Flemming Forsberg ◽  
William T. Shi ◽  
Michael K. Knauer ◽  
Anne L. Hall ◽  
Chris Vecchio ◽  
...  

A new nonlinear contrast specific imaging modality, excitation-enhanced imaging (EEI) has been implemented on commercially-available scanners for real-time imaging. This novel technique employs two acoustic fields: a low-frequency, high-intensity ultrasound field (the excitation field) to actively condition contrast microbubbles, and a second lower-intensity regular imaging field applied shortly afterwards to detect enhanced contrast scattering. A Logiq 9 scanner (GE Healthcare, Milwaukee, WI) with a 3.5C curved linear array and an AN2300 digital ultrasound engine (Analogic Corporation, Peabody, MA) with a P4-2 phased array transducer (Philips Medical Systems, Bothell, WA) were modified to perform EEI on a vector-by-vector basis in fundamental and pulse inversion harmonic grayscale modes. Ultrasound contrast microbubbles within an 8 mm vessel embedded in a tissue-mimicking flow phantom (ATS Laboratories, Bridgeport, CT) were imaged in vitro. While video intensities of scattered signals from the surrounding tissue were unchanged, video intensities of echoes from contrast bubbles within the vessel were markedly enhanced. The maximum enhancement achieved was 10.4 dB in harmonic mode (mean enhancement: 6.3 dB; p=0.0007). In conclusion, EEI may improve the sensitivity of ultrasound contrast imaging, but further work is required to assess the in vivo potential of this new technique.


2013 ◽  
Vol 60 (10) ◽  
pp. 2065-2078 ◽  
Author(s):  
Fanglue Lin ◽  
Christian Cachard ◽  
Riccardo Mori ◽  
Francois Varray ◽  
Francesco Guidi ◽  
...  

Author(s):  
A. Novell ◽  
S. M. van der Meer ◽  
M. Versluis ◽  
N. de Jong ◽  
A. Bouakaz

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