Changes in regional cerebral blood volume in frontal cortex during mental work with and without caffeine intake: functional monitoring using near-infrared spectroscopy

2004 ◽  
Vol 9 (4) ◽  
pp. 788 ◽  
Author(s):  
Terumasa Higashi ◽  
Yukari Sone ◽  
Kanta Ogawa ◽  
Yuri T. Kitamura ◽  
Kayoko Saiki ◽  
...  
2001 ◽  
Vol 21 (2) ◽  
pp. 110-113 ◽  
Author(s):  
Marjo J. T. Van de Ven ◽  
Willy N. J. M. Colier ◽  
Marco C. van der Sluijs ◽  
Diederik Walraven ◽  
Berend Oeseburg ◽  
...  

In some circumstances, cerebral blood volume (CBV) can be used as a measure for cerebral blood flow. A new near infrared spectroscope was used for determining the reproducibility of CBV measurements assessed by the O2-method. Twenty-seven healthy subjects were investigated. An intrasubject coefficient of variation (CV) was calculated, based on four identical episodes of desaturation–resaturation (O2-method) procedures for CBV measurements. Two trials were performed, with (trial 1) and without (trial 2) disconnecting the equipment. A mean CV of 12.6% and 10.0% was found in trial 1 and 2, respectively. Cerebral blood volume values yield 3.60 ± 0.82 mL 100 g−1. Cerebral blood volume could be measured reproducible in adults using near infrared spectroscopy, if the arterial desaturation is limited to approximately 5% from baseline level.


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