scholarly journals Impact of heat on metabolic and hemodynamic changes in transcranial infrared laser stimulation measured by broadband near-infrared spectroscopy

2017 ◽  
Vol 5 (01) ◽  
pp. 1 ◽  
Author(s):  
Xinlong Wang ◽  
Divya D. Reddy ◽  
Sahil S. Nalawade ◽  
Suvra Pal ◽  
F. Gonzalez-Lima ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Infrared Laser ◽  
Hemodynamic Changes ◽  
Laser Stimulation

scholarly journals Up-regulation of cerebral cytochrome-c-oxidase and hemodynamics by transcranial infrared laser stimulation: A broadband near-infrared spectroscopy study

2017 ◽  
Vol 37 (12) ◽  
pp. 3789-3802 ◽  
Author(s):  
Xinlong Wang ◽  
Fenghua Tian ◽  
Divya D Reddy ◽  
Sahil S Nalawade ◽  
Douglas W Barrett ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Cytochrome C ◽  
Cytochrome C Oxidase ◽  
Near Infrared Spectroscopy ◽  
Time Course ◽  
Near Infrared ◽  
Cerebral Metabolism ◽  
Infrared Laser ◽  
Cortical Region ◽  
Laser Stimulation

Transcranial infrared laser stimulation (TILS) is a noninvasive form of brain photobiomulation. Cytochrome-c-oxidase (CCO), the terminal enzyme in the mitochondrial electron transport chain, is hypothesized to be the primary intracellular photoacceptor. We hypothesized that TILS up-regulates cerebral CCO and causes hemodynamic changes. We delivered 1064-nm laser stimulation to the forehead of healthy participants ( n = 11), while broadband near-infrared spectroscopy was utilized to acquire light reflectance from the TILS-treated cortical region before, during, and after TILS. Placebo experiments were also performed for accurate comparison. Time course of spectroscopic readings were analyzed and fitted to the modified Beer–Lambert law. With respect to the placebo readings, we observed (1) significant increases in cerebral concentrations of oxidized CCO (Δ[CCO]; >0.08 µM; p < 0.01), oxygenated hemoglobin (Δ[HbO]; >0.8 µM; p < 0.01), and total hemoglobin (Δ[HbT]; >0.5 µM; p < 0.01) during and after TILS, and (2) linear interplays between Δ[CCO] versus Δ[HbO] and between Δ[CCO] versus Δ[HbT]. Ratios of Δ[CCO]/Δ[HbO] and Δ[CCO]/Δ[HbT] were introduced as TILS-induced metabolic-hemodynamic coupling indices to quantify the coupling strength between TILS-enhanced cerebral metabolism and blood oxygen supply. This study provides the first demonstration that TILS causes up-regulation of oxidized CCO in the human brain, and contributes important insight into the physiological mechanisms.

scholarly journals Hemodynamic changes in visual motion detection measured by near infrared spectroscopy

2010 ◽  
Vol 6 (6) ◽  
pp. 572-572 ◽  
Author(s):  
M. Harasawa ◽  
A. Obata ◽  
T. Morita ◽  
T. Ito ◽  
T. Saito ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Motion Detection ◽  
Near Infrared ◽  
Visual Motion ◽  
Hemodynamic Changes ◽  
Visual Motion Detection

scholarly journals Transcranial Laser Stimulation Research—A New Helmet and First Data from Near Infrared Spectroscopy

Medicines ◽  
2018 ◽  
Vol 5 (3) ◽  
pp. 97 ◽  
Author(s):  
Gerhard Litscher
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Laser Stimulation

This editorial adopts a future-oriented technology. It describes a new modern helmet for transcranial laser stimulation and a way to quantify effects of this possible therapeutical method using near-infrared spectroscopy.

Hemodynamic Changes in the Prefrontal Cortex during Digit Span Task: A Near-Infrared Spectroscopy Study

2011 ◽  
Vol 63 (2) ◽  
pp. 59-65 ◽  
Author(s):  
Hitoshi Kaneko ◽  
Toru Yoshikawa ◽  
Kenji Nomura ◽  
Hiroyuki Ito ◽  
Hoshiko Yamauchi ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Digit Span ◽  
Span Task ◽  
Spectroscopy Study ◽  
Hemodynamic Changes

scholarly journals Measuring brain hemodynamic changes in a songbird: responses to hypercapnia measured with functional MRI and near-infrared spectroscopy

2008 ◽  
Vol 53 (10) ◽  
pp. 2457-2470 ◽  
Author(s):  
C Vignal ◽  
T Boumans ◽  
B Montcel ◽  
S Ramstein ◽  
M Verhoye ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Functional Mri ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Hemodynamic Changes
Sign in / Sign up

Export Citation Format

Share Document