scholarly journals Influence of probe pressure on the pulsatile diffuse correlation spectroscopy blood flow signal on the forearm and forehead regions

2019 ◽  
Vol 6 (03) ◽  
pp. 1 ◽  
Author(s):  
Detian Wang ◽  
Wesley B. Baker ◽  
Hui He ◽  
Peng Gao ◽  
Liguo Zhu ◽  
...  
Keyword(s):  
Blood Flow ◽  
Correlation Spectroscopy ◽  
Diffuse Correlation Spectroscopy ◽  
Flow Signal ◽  
Blood Flow Signal

scholarly journals Influence of probe pressure on the diffuse correlation spectroscopy blood flow signal: extra-cerebral contributions

2013 ◽  
Vol 4 (7) ◽  
pp. 978 ◽  
Author(s):  
Rickson C. Mesquita ◽  
Steven S. Schenkel ◽  
David L. Minkoff ◽  
Xiangping Lu ◽  
Christopher G. Favilla ◽  
...  
Keyword(s):  
Blood Flow ◽  
Correlation Spectroscopy ◽  
Diffuse Correlation Spectroscopy ◽  
Flow Signal ◽  
Blood Flow Signal

scholarly journals AB0425 PRELIMINARY EVALUATION OF THE SURAL NERVE USING 24-MHZ ULTRASOUND: A NEW APPROACH TO EVALUATE SURAL NEUROPATHY OF SJOGREN’S SYNDROME PATIENTS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1512.2-1512
Author(s):  
F. Liu ◽  
J. Zhu ◽  
S. Zhang ◽  
D. LI ◽  
F. Liu ◽  
...  
Keyword(s):  
Blood Flow ◽  
Sjögren’S Syndrome ◽  
Sural Nerve ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Primary Sjögren’S Syndrome ◽  
Flow Signal ◽  
Blood Flow Signal ◽  
Sjögren‘S Syndrome

Background:Peripheral neuropathy is one of the most frequent extraglandular manifestations of primary Sjögren’s syndrome (pSS). The diagnosis of peripheral neuropathy complications of pSS is based primarily on careful neurologic examination and electrodiagnostic tests. The value of ultrasound in peripheral nerve has been recognized. However, little clinical researches have focused specifically on cutaneous nerve of pSS.Objectives:To evaluate the morphological changes of sural nerve in patients with pSS by high-frequency ultrasound.Methods:The prospective study subjects consisted of 31 consecutive pSS patients underwent sural nerve biopsy and 30 healthy volunteers as controls. The ultrasonic presentations of the fascicle, perineurium, epineurium of sural nerve were observed, and the cross-sectional areas (CSA) of the sural nerves was measured.Results:Among the 21 sural nerves confirmed by pathology, all showed the thickening of the perineurium and epineurium (Figure 1-2), and abnormal blood flow signal in perineurium or epineurium in 14 cases (Figure 2). The mean CSAs were (1.41±0.44) mm2 for the control group, and (1.58±0.48) mm2 for the case group (P>0.05). In addition, the abnormal blood flow signal in sural nerve correlated with disease activity.Conclusion:This study indicated that high-frequency ultrasound may be a valuable tool for evaluating cutaneous nerve neuropathy of Sjogren’s syndrome patients.References:[1]Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE, et al. Classification criteria for Sjögren’s syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis. 2002;61(6):554-8.[2]Terrier B, Lacroix C, Guillevin L, Hatron PY, Dhote R, Maillot F, et al. Diagnostic and prognostic relevance of neuromuscular biopsy in primary Sjögren’s syndrome-related neuropathy. Arthritis Rheum.2007;57(8):1520-9.[3]McCoy SS, Baer AN. Neurological Complications of Sjögren’s Syndrome: Diagnosis and Management. Curr Treatm Opt Rheumatol. 2017;3(4):275-88.[4]Carvajal Alegria G, Guellec D, Devauchelle-Pensec V, Saraux A. Is there specific neurological disorders of primary Sjögren’s syndrome? Joint Bone Spine. 2015;82(2):86-9.Figure 1.Transverse sonograms of the sural nerve (arrows) V: indicates lesser saphenous veinFigure 2.Longitudinal sonograms of the sural nerve (arrows) The sonogram of sural nerve showed abnormal blood flow signal. V indicates lesser saphenous vein.Acknowledgments:This work was partly supported by National Natural Science Foundation of China (No. 81701712).Disclosure of Interests: :None declared

Modifying the Cosine Model for Nonstationary Blood Flow Signal Simulation

2003 ◽  
Vol 22 (3) ◽  
pp. 281-285 ◽  
Author(s):  
Sedigheh Ghofrani ◽  
Ahmad Ayatollahi ◽  
Mohammad Bagher Shamsollahi
Keyword(s):  
Blood Flow ◽  
Flow Signal ◽  
Blood Flow Signal ◽  
Signal Simulation

scholarly journals Evaluation of Local Skeletal Muscle Blood Flow in Manipulative Therapy by Diffuse Correlation Spectroscopy

2022 ◽  
Vol 9 ◽  
Author(s):  
Yasuhiro Matsuda ◽  
Mikie Nakabayashi ◽  
Tatsuya Suzuki ◽  
Sinan Zhang ◽  
Masashi Ichinose ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Skeletal Muscle ◽  
Blood Flow ◽  
Muscle Blood Flow ◽  
Nervous Activity ◽  
Correlation Spectroscopy ◽  
Autonomic Nervous Activity ◽  
Local Blood Flow ◽  
Diffuse Correlation Spectroscopy ◽  
Manipulative Therapy

Manipulative therapy (MT) is applied to motor organs through a therapist’s hands. Although MT has been utilized in various medical treatments based on its potential role for increasing the blood flow to the local muscle, a quantitative validation of local muscle blood flow in MT remains challenging due to the lack of appropriate bedside evaluation techniques. Therefore, we investigated changes in the local blood flow to the muscle undergoing MT by employing diffuse correlation spectroscopy, a portable and emerging optical measurement technology that non-invasively measures blood flow in deep tissues. This study investigated the changes in blood flow, heart rate, blood pressure, and autonomic nervous activity in the trapezius muscle through MT application in 30 volunteers without neck and shoulder injury. Five minutes of MT significantly increased the median local blood flow relative to that of the pre-MT period (p < 0.05). The post-MT local blood flow increase was significantly higher in the MT condition than in the control condition, where participants remained still without receiving MT for the same time (p < 0.05). However, MT did not affect the heart rate, blood pressure, or cardiac autonomic nervous activity. The post-MT increase in muscle blood flow was significantly higher in the participants with muscle stiffness in the neck and shoulder regions than in those without (p < 0.05). These results suggest that MT could increase the local blood flow to the target skeletal muscle, with minimal effects on systemic circulatory function.

Impact of Changes in Tissue Optical Properties on Near-Infrared Diffuse Correlation Spectroscopy Measures of Skeletal Muscle Blood Flow

2021 ◽  
Author(s):  
Miles F. Bartlett ◽  
Scott M. Jordan ◽  
Dennis M. Hueber ◽  
Michael D. Nelson
Keyword(s):  
Skeletal Muscle ◽  
Blood Flow ◽  
Optical Properties ◽  
Near Infrared ◽  
Muscle Blood Flow ◽  
Reactive Hyperemia ◽  
Correlation Spectroscopy ◽  
Skeletal Muscle Blood Flow ◽  
Diffuse Correlation Spectroscopy ◽  
Tissue Optical Properties

Near-infrared diffuse correlation spectroscopy (DCS) is increasingly utilized to study relative changes in skeletal muscle blood flow. However, most diffuse correlation spectrometers assume that tissue optical properties- such as absorption (μa) and reduced scattering (μ's) coefficients- remain constant during physiological provocations, which is untrue for skeletal muscle. Here, we interrogate how changes in tissue μa and μ's affect DCS calculations of blood flow index (BFI). We recalculated BFI using raw autocorrelation curves and μa/μ's values recorded during a reactive hyperemia protocol in 16 healthy young individuals. First, we show that incorrectly assuming baseline μa and μ's substantially affects peak BFI and BFI slope when expressed in absolute terms (cm2/s, p<0.01) but these differences are abolished when expressed in relative terms (% baseline). Next, to evaluate the impact of physiologic changes in μa and μ's, we compared peak BFI and BFI slope when μa and μ's were held constant throughout the reactive hyperemia protocol versus integrated from a 3s-rolling average. Regardless of approach, group means for peak BFI and BFI slope did not differ. Group means for peak BFI and BFI slope were also similar following ad absurdum analyses, where we simulated supraphysiologic changes in μa/μ's. In both cases, however, we identified individual cases where peak BFI and BFI slope were indeed affected, with this result being driven by relative changes in μa over μ's. Overall, these results provide support for past reports in which μa/μ's were held constant but also advocate for real-time incorporation of μa and μ's moving forward.

Cerebral Blood Flow of the Neonatal Brain after Hypoxic-Ischemic Injury

2021 ◽  
Author(s):  
Luis Octavio Tierradentro-García ◽  
Sandra Saade-Lemus ◽  
Colbey Freeman ◽  
Matthew Kirschen ◽  
Hao Huang ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Near Infrared ◽  
Imaging Modality ◽  
Brain Perfusion ◽  
Correlation Spectroscopy ◽  
Therapeutic Interventions ◽  
Routine Practice ◽  
Diffuse Correlation Spectroscopy ◽  
Positron Emission

Objective Hypoxic-ischemic encephalopathy (HIE) in infants can have long-term adverse neurodevelopmental effects and markedly reduce quality of life. Both the initial hypoperfusion and the subsequent rapid reperfusion can cause deleterious effects in brain tissue. Cerebral blood flow (CBF) assessment in newborns with HIE can help detect abnormalities in brain perfusion to guide therapy and prognosticate patient outcomes. Study Design The review will provide an overview of the pathophysiological implications of CBF derangements in neonatal HIE, current and emerging techniques for CBF quantification, and the potential to utilize CBF as a physiologic target in managing neonates with acute HIE. Conclusion The alterations of CBF in infants during hypoxia-ischemia have been studied by using different neuroimaging techniques, including nitrous oxide and xenon clearance, transcranial Doppler ultrasonography, contrast-enhanced ultrasound, arterial spin labeling MRI, 18F-FDG positron emission tomography, near-infrared spectroscopy (NIRS), functional NIRS, and diffuse correlation spectroscopy. Consensus is lacking regarding the clinical significance of CBF estimations detected by these different modalities. Heterogeneity in the imaging modality used, regional versus global estimations of CBF, time for the scan, and variables impacting brain perfusion and cohort clinical characteristics should be considered when translating the findings described in the literature to routine practice and implementation of therapeutic interventions. Key Points

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