multiple kernel learning
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Author(s):  
Santhoshkumar SP ◽  
Kumar M Praveen ◽  
Beaulah H Lilly

Video has more information than the isolated images. Processing, analyzing and understanding of contents present in videos are becoming very important. Consumer videos are generally captured by amateurs using handheld cameras of events and it contains considerable camera motion, occlusion, cluttered background, and large intraclass variations within the same type of events, making their visual cues highly variable and less discriminant. So visual event recognition is an extremely challenging task in computer vision. A visual event recognition framework for consumer videos is framed by leveraging a large amount of loosely labeled web videos. The videos are divided into training and testing sets manually. A simple method called the Aligned Space-Time Pyramid Matching method was proposed to effectively measure the distances between two video clips from different domains. Each video is divided into space-time volumes over multiple levels. A new transfer learning method is referred to as Adaptive Multiple Kernel Learning fuse the information from multiple pyramid levels, features, and copes with the considerable variation in feature distributions between videos from two domains web video domain and consumer video domain.With the help of MATLAB Simulink videos are divided and compared with web domain videos. The inputs are taken from the Kodak data set and the results are given in the form of MATLAB simulation.


Genes ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1872
Author(s):  
Yingxia Li ◽  
Ulrich Mansmann ◽  
Shangming Du ◽  
Roman Hornung

Lung adenocarcinoma (LUAD) is a common and very lethal cancer. Accurate staging is a prerequisite for its effective diagnosis and treatment. Therefore, improving the accuracy of the stage prediction of LUAD patients is of great clinical relevance. Previous works have mainly focused on single genomic data information or a small number of different omics data types concurrently for generating predictive models. A few of them have considered multi-omics data from genome to proteome. We used a publicly available dataset to illustrate the potential of multi-omics data for stage prediction in LUAD. In particular, we investigated the roles of the specific omics data types in the prediction process. We used a self-developed method, Omics-MKL, for stage prediction that combines an existing feature ranking technique Minimum Redundancy and Maximum Relevance (mRMR), which avoids redundancy among the selected features, and multiple kernel learning (MKL), applying different kernels for different omics data types. Each of the considered omics data types individually provided useful prediction results. Moreover, using multi-omics data delivered notably better results than using single-omics data. Gene expression and methylation information seem to play vital roles in the staging of LUAD. The Omics-MKL method retained 70 features after the selection process. Of these, 21 (30%) were methylation features and 34 (48.57%) were gene expression features. Moreover, 18 (25.71%) of the selected features are known to be related to LUAD, and 29 (41.43%) to lung cancer in general. Using multi-omics data from genome to proteome for predicting the stage of LUAD seems promising because each omics data type may improve the accuracy of the predictions. Here, methylation and gene expression data may play particularly important roles.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Ayyüce Begüm Bektaş ◽  
Mehmet Gönen

Abstract Background Identification of molecular mechanisms that determine tumour progression in cancer patients is a prerequisite for developing new disease treatment guidelines. Even though the predictive performance of current machine learning models is promising, extracting significant and meaningful knowledge from the data simultaneously during the learning process is a difficult task considering the high-dimensional and highly correlated nature of genomic datasets. Thus, there is a need for models that not only predict tumour volume from gene expression data of patients but also use prior information coming from pathway/gene sets during the learning process, to distinguish molecular mechanisms which play crucial role in tumour progression and therefore, disease prognosis. Results In this study, instead of initially choosing several pathways/gene sets from an available set and training a model on this previously chosen subset of genomic features, we built a novel machine learning algorithm, PrognosiT, that accomplishes both tasks together. We tested our algorithm on thyroid carcinoma patients using gene expression profiles and cancer-specific pathways/gene sets. Predictive performance of our novel multiple kernel learning algorithm (PrognosiT) was comparable or even better than random forest (RF) and support vector regression (SVR). It is also notable that, to predict tumour volume, PrognosiT used gene expression features less than one-tenth of what RF and SVR algorithms used. Conclusions PrognosiT was able to obtain comparable or even better predictive performance than SVR and RF. Moreover, we demonstrated that during the learning process, our algorithm managed to extract relevant and meaningful pathway/gene sets information related to the studied cancer type, which provides insights about its progression and aggressiveness. We also compared gene expressions of the selected genes by our algorithm in tumour and normal tissues, and we then discussed up- and down-regulated genes selected by our algorithm while learning, which could be beneficial for determining new biomarkers.


2021 ◽  
Author(s):  
Shervin Rahimzadeh Arashloo

The paper addresses the one-class classification (OCC) problem and advocates a one-class multiple kernel learning (MKL) approach for this purpose. To this aim, based on the Fisher null-space one-class classification principle, we present a multiple kernel learning algorithm where an $\ell_p$-norm constraint ($p\geq1$) on kernel weights is considered. We cast the proposed one-class MKL task as a min-max saddle point Lagrangian optimisation problem and propose an efficient method to solve it. An extension of the proposed one-class MKL approach is also considered where several related one-class MKL tasks are learned concurrently by constraining them to share common kernel weights. <br>An extensive assessment of the proposed method on a range of data sets from different application domains confirms its merits against the baseline and several other algorithms.<br>


2021 ◽  
Author(s):  
Shervin Rahimzadeh Arashloo

The paper addresses the one-class classification (OCC) problem and advocates a one-class multiple kernel learning (MKL) approach for this purpose. To this aim, based on the Fisher null-space one-class classification principle, we present a multiple kernel learning algorithm where an $\ell_p$-norm constraint ($p\geq1$) on kernel weights is considered. We cast the proposed one-class MKL task as a min-max saddle point Lagrangian optimisation problem and propose an efficient method to solve it. An extension of the proposed one-class MKL approach is also considered where several related one-class MKL tasks are learned concurrently by constraining them to share common kernel weights. <br>An extensive assessment of the proposed method on a range of data sets from different application domains confirms its merits against the baseline and several other algorithms.<br>


2021 ◽  
Vol 15 ◽  
Author(s):  
Xiaocheng Zhou ◽  
Qingmin Lin ◽  
Yuanyuan Gui ◽  
Zixin Wang ◽  
Manhua Liu ◽  
...  

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common brain diseases among children. The current criteria of ADHD diagnosis mainly depend on behavior analysis, which is subjective and inconsistent, especially for children. The development of neuroimaging technologies, such as magnetic resonance imaging (MRI), drives the discovery of brain abnormalities in structure and function by analyzing multimodal neuroimages for computer-aided diagnosis of brain diseases. This paper proposes a multimodal machine learning framework that combines the Boruta based feature selection and Multiple Kernel Learning (MKL) to integrate the multimodal features of structural and functional MRIs and Diffusion Tensor Images (DTI) for the diagnosis of early adolescent ADHD. The rich and complementary information of the macrostructural features, microstructural properties, and functional connectivities are integrated at the kernel level, followed by a support vector machine classifier for discriminating ADHD from healthy children. Our experiments were conducted on the comorbidity-free ADHD subjects and covariable-matched healthy children aged 9–10 chosen from the Adolescent Brain and Cognitive Development (ABCD) study. This paper is the first work to combine structural and functional MRIs with DTI for early adolescents of the ABCD study. The results indicate that the kernel-level fusion of multimodal features achieves 0.698 of AUC (area under the receiver operating characteristic curves) and 64.3% of classification accuracy for ADHD diagnosis, showing a significant improvement over the early feature fusion and unimodal features. The abnormal functional connectivity predictors, involving default mode network, attention network, auditory network, and sensorimotor mouth network, thalamus, and cerebellum, as well as the anatomical regions in basal ganglia, are found to encode the most discriminative information, which collaborates with macrostructure and diffusion alterations to boost the performances of disorder diagnosis.


2021 ◽  
Author(s):  
Qiang Hu ◽  
Yuelong Zhu ◽  
Hexuan Hu ◽  
Zhuang Guan ◽  
Zeyu Qian ◽  
...  

Abstract This paper proposes a new technology of spatial prediction for flood susceptibility. Multiple kernel learning was used to build the flood susceptibility model and predict the flood inundation risk of the Sanhuajian Basin of the Yellow River. Based on the historical flow records of the Huayuankou Site and the MODIS remote sensing images of the study area, the maximum inundation range was extracted by the open water likelihood index method, and the flooded and non-flooded sample sites were selected. Considering the availability of pertinent literatures and data, ten flood conditioning factors were defined as the sample characteristics. The model performance was evaluated in terms of accuracy, F1 score, and AUC. According to the results, multiple kernel learning significantly outperforms the support vector machine adopting single kernel, and NLMKL demonstrates the best comprehensive performance. The flood susceptibility map generated by MODIS remote sensing images and multiple kernel learning, therefore, can provide effective help for researchers and decision makers in flood management.


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