Cavity ring down spectrometry for disease diagnostics using exhaled air

Author(s):  
Gita Revalde ◽  
Janis Alnis ◽  
Kārlis Grundsteins ◽  
Atis Skudra
2020 ◽  
Author(s):  
Gita Revalde ◽  
Karlis Grundsteins ◽  
Anda Abola
Keyword(s):  

Author(s):  
Gita Revalde ◽  
Karlis Grundsteins ◽  
Janis Alnis ◽  
Atis Skudra

2020 ◽  
Vol 30 (4) ◽  
pp. 94-105
Author(s):  
L. V. Novikov ◽  
◽  
V. V. Manoilov ◽  
A. G. Kuzmin ◽  
Yu. A. Titov ◽  
...  

The method is proposed for express diagnostics of diseases according to the data of mass spectrometric analysis of exhaled air. An algorithm for calculating the probability of diseases has been developed and tested. The results of data processing of patients treated in two oncological clinics are presented. The calculation of the probability of disease according to the data of mass spectrometric analysis of exhaled air is based on attributing the mass spectrum of the tested patient to the mass-spectra of the corresponding control group. Each control group is formed by collecting an array of spectra from at least ten patients with the same disease. Diagnostics is performed by transforming the matrix of spectra of the control group and the spectrum of a patient being tested into the space of the principal components. The probability of a disease is determined by the Euclidean distance of the patient's coordinates from the centroid of the control group in the multidimensional space of these principal components.


1987 ◽  
Vol 26 (03) ◽  
pp. 143-146 ◽  
Author(s):  
H. Fill ◽  
M. Oberladstätter ◽  
J. W. Krzesniak

The mean activity concentration of1311 during inhalation by the nuclear medicine personnel was measured at therapeutic activity applications of 22 GBq (600 mCi) per week. The activity concentration reached its maximum in the exhaled air of the patients 2.5 to 4 hours after oral application. The normalized maximum was between 2 • 10−5 and 2 • 10−3 Bq-m−3 per administered Bq. The mean activity concentration of1311 inhaled by the personnel was 28 to 1300 Bq-m−3 (0.8 to 35 nCi-rrf−3). From this the1311 uptake per year was estimated to be 30 to 400 kBq/a (x̄ = 250, SD = 50%). The maximum permitted uptake from air per year is, according to the German and Austrian radiation protection ordinances 22/21 µiCi/a (= 8 • 105 Bq/a). At maximum 50% and, on the average, 30% of this threshold value are reached. The length of stay of the personnel in the patient rooms is already now limited to such an extent that 10% of the maximum permissible whole-body dose for external radiation is not exceeded. Therefore, increased attention should be paid also to radiation exposure by inhalation.


2014 ◽  
Vol 134 (8) ◽  
pp. 243-246
Author(s):  
Yuki Hirabayashi ◽  
Hirokazu Tanimoto ◽  
Yoshinobu Maeda

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