Nonclinical applications of quantitative whole-body autoradiography, and imaging mass spectrometry in drug discovery and development

Visualizing and Quantifying Drug Distribution in Tissue IV ◽

10.1117/12.2551441 ◽

2020 ◽

Author(s):

Eric G. Solon

Keyword(s):

Mass Spectrometry ◽

Drug Discovery ◽

Imaging Mass Spectrometry ◽

Drug Discovery And Development ◽

Whole Body Autoradiography

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Imaging mass spectrometry in drug discovery and development

Bioanalysis ◽

10.4155/bio.15.202 ◽

2015 ◽

Vol 7 (20) ◽

pp. 2609-2610 ◽

Author(s):

Stacey R Oppenheimer ◽

Angela Y Wehr

Keyword(s):

Mass Spectrometry ◽

Drug Discovery ◽

Imaging Mass Spectrometry ◽

Drug Discovery And Development

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Imaging Mass Spectrometry (IMS) for drug discovery and development survey: Results on methods, applications and regulatory compliance

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2021.100438 ◽

2021 ◽

pp. 100438

Author(s):

Eric Solon ◽

M. Reid Groseclose ◽

Stacy Ho ◽

Kouji Tanaka ◽

Naoyuki Nakada ◽

...

Keyword(s):

Mass Spectrometry ◽

Drug Discovery ◽

Imaging Mass Spectrometry ◽

Regulatory Compliance ◽

Drug Discovery And Development ◽

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The emergence of imaging mass spectrometry in drug discovery and development: Making a difference by driving decision making

Journal of Mass Spectrometry ◽

10.1002/jms.4563 ◽

2021 ◽

Vol 56 (8) ◽

Author(s):

Steve Castellino ◽

Nichole Lareau ◽

Reid Groseclose

Keyword(s):

Mass Spectrometry ◽

Decision Making ◽

Drug Discovery ◽

Imaging Mass Spectrometry ◽

Drug Discovery And Development ◽

Making A Difference

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Utility of quantitative whole-body autoradiography (QWBA) and imaging mass spectrometry (IMS) by matrix-assisted laser desorption/ionization (MALDI) in the assessment of ocular distribution of drugs

Journal of Pharmacological and Toxicological Methods ◽

10.1016/j.vascn.2010.10.003 ◽

2011 ◽

Vol 63 (2) ◽

pp. 205-208 ◽

Author(s):

Dieter M. Drexler ◽

Sarah H. Tannehill-Gregg ◽

Lifei Wang ◽

Barry J. Brock

Keyword(s):

Mass Spectrometry ◽

Imaging Mass Spectrometry ◽

Laser Desorption ◽

Laser Desorption Ionization ◽

Desorption Ionization ◽

Whole Body Autoradiography ◽

Ocular Distribution ◽

Matrix Assisted Laser ◽

Matrix Assisted Laser Desorption

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Whole-Body Autoradiography and Microautoradiography in Drug Discovery and Development

Encyclopedia of Drug Metabolism and Interactions ◽

10.1002/9780470921920.edm103 ◽

2012 ◽

Author(s):

Eric G. Solon

Keyword(s):

Drug Discovery ◽

Drug Discovery And Development ◽

Whole Body Autoradiography

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Applications of Quantitative Whole-Body Autoradiography (QWBA) in Drug Discovery and Development

ADME-Enabling Technologies in Drug Design and Development ◽

10.1002/9781118180778.ch27 ◽

2012 ◽

pp. 419-434 ◽

Author(s):

Lifei Wang ◽

Haizheng Hong ◽

Donglu Zhang

Keyword(s):

Drug Discovery ◽

Drug Discovery And Development ◽

Whole Body Autoradiography

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10th international symposium on the synthesis and applications of isotopes and isotopically labelled compounds-whole-body autoradiography (WBA)-drug discovery and development Session 3: Monday, June 15, 2009

Journal of Labelled Compounds and Radiopharmaceuticals ◽

10.1002/jlcr.1763 ◽

2010 ◽

Vol 53 (5-6) ◽

pp. 269-274

Author(s):

Brian Whitby ◽

Alfred Lordi

Keyword(s):

Drug Discovery ◽

International Symposium ◽

Drug Discovery And Development ◽

Whole Body Autoradiography ◽

10Th International Symposium

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A systematic approach to development of analytical scale and microflow-based liquid chromatography coupled to mass spectrometry metabolomics methods to support drug discovery and development

Journal of Chromatography A ◽

10.1016/j.chroma.2021.462047 ◽

2021 ◽

Vol 1642 ◽

pp. 462047

Author(s):

Sarah Geller ◽

Harvey Lieberman ◽

Alla Kloss ◽

Alexander R. Ivanov

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Drug Discovery ◽

Systematic Approach ◽

Drug Discovery And Development ◽

Analytical Scale

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Application of Imaging Mass Spectrometry for Drug Discovery

YAKUGAKU ZASSHI ◽

10.1248/yakushi.15-00226-4 ◽

2016 ◽

Vol 136 (2) ◽

pp. 163-170 ◽

Author(s):

Takahiro Hayasaka

Keyword(s):

Mass Spectrometry ◽

Drug Discovery ◽

Imaging Mass Spectrometry

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Direct Molecular Analysis of Whole-Body Animal Tissue Sections by MALDI Imaging Mass Spectrometry

Methods in Molecular Biology - Mass Spectrometry Imaging ◽

10.1007/978-1-60761-746-4_17 ◽

2010 ◽

pp. 285-301 ◽

Author(s):

Michelle L. Reyzer ◽

Pierre Chaurand ◽

Peggi M. Angel ◽

Richard M. Caprioli

Keyword(s):

Mass Spectrometry ◽

Molecular Analysis ◽

Imaging Mass Spectrometry ◽

Animal Tissue ◽

Maldi Imaging ◽

Tissue Sections ◽

Maldi Imaging Mass Spectrometry

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