Low cost plastic optical fiber sensor based on surface plasmon resonance

Surface Plasmon Resonance (SPR)-based plastic optical fiber sensor for estimating the concentration and refractive index of sugar in human blood serum. The sensor is fabricated by a small part (10mm) of optical fiber in the middle is embedded in a resin block and then the polishing process is done, after that it is deposited with about (40nm) thickness of gold metal. The blood serum is placed on gold coated core of an Optical grade plastic optical fiber of 980 µm core diameter.

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Design and validation of fiber optic localized surface plasmon resonance sensor for thyroglobulin immunoassay with high sensitivity and rapid detection

Scientific Reports ◽

10.1038/s41598-021-95375-y ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Hyeong-Min Kim ◽

Dae Hong Jeong ◽

Ho-Young Lee ◽

Jae-Hyoung Park ◽

Seung-Ki Lee

Keyword(s):

Surface Plasmon Resonance ◽

Optical Fiber ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Localized Surface Plasmon Resonance ◽

Optical Fiber Sensor ◽

Fiber Sensor ◽

Localized Surface Plasmon ◽

Simple Method ◽

Resonance Sensor

AbstractA simple optical fiber sensor based on localized surface plasmon resonance was constructed for direct and rapid measurement of thyroglobulin (Tg). Specific tests for Tg in patients that have undergone thyroidectomy are limited because of insufficient sensitivity, complicated procedures, and in some cases, a long time to yield a result. A sensitive, fast, and simple method is necessary to relieve the psychological and physical burden of the patient. Various concentrations of Tg were measured in a microfluidic channel using an optical fiber sensor with gold nanoparticles. The sensor chip has a detection limit of 93.11 fg/mL with no specificity for other antigens. The potential applicability of the Tg sensing system was evaluated using arbitrary samples containing specific concentrations of Tg. Finally, the sensor can be employed to detect Tg in the patient’s serum, with a good correlation when compared with the commercial kit.

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An Enhanced Plastic Optical Fiber-Based Surface Plasmon Resonance Sensor with a Double-Sided Polished Structure

Sensors ◽

10.3390/s21041516 ◽

2021 ◽

Vol 21 (4) ◽

pp. 1516

Author(s):

Lian Liu ◽

Shijie Deng ◽

Jie Zheng ◽

Libo Yuan ◽

Hongchang Deng ◽

...

Keyword(s):

Surface Plasmon Resonance ◽

Optical Fiber ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Low Cost ◽

Fiber Axis ◽

Plastic Optical Fiber ◽

Au Film ◽

Spr Sensor ◽

Resonance Sensor

An enhanced plastic optical fiber (POF)-based surface plasmon resonance (SPR) sensor is proposed by employing a double-sided polished structure. The sensor is fabricated by polishing two sides of the POF symmetrically along with the fiber axis, and a layer of Au film is deposited on each side of the polished region. The SPR can be excited on both polished surfaces with Au film coating, and the number of light reflections will be increased by using this structure. The simulation and experimental results show that the proposed sensor has an enhanced SPR effect. The visibility and full width at half maximum (FWHM) of spectrum can be improved for the high measured refractive index (RI). A sensitivity of 4284.8 nm/RIU is obtained for the double-sided POF-based SPR sensor when the measured liquid RI is 1.42. The proposed SPR sensor is easy fabrication and low cost, which can provide a larger measurement range and action area to the measured samples, and it has potential application prospects in the oil industry and biochemical sensing fields.

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