SU-E-T-427: Cell Surviving Fractions Derived From Tumor-Volume Variation During Radiotherapy for Non-Small Cell Lung Cancer: Comparison with Predictive Assays

2014 ◽  
Vol 41 (6Part18) ◽  
pp. 324-324
Author(s):  
A Chvetsov ◽  
S Yartsev ◽  
J Schwartz ◽  
N Mayr
2009 ◽  
Vol 36 (6Part22) ◽  
pp. 2722-2722
Author(s):  
A Chvetsov ◽  
L Dong ◽  
S Tucker ◽  
J Palta ◽  
N Mendenhall

2020 ◽  
Vol 61 (5) ◽  
pp. 740-746
Author(s):  
Nam Vu ◽  
Hiroshi Onishi ◽  
Masahide Saito ◽  
Kengo Kuriyama ◽  
Takafumi Komiyama ◽  
...  

Abstract The purpose of the study was to investigate the association between tumor volume changes during stereotactic body radiation therapy (SBRT) and prognoses in stage I non-small-cell lung cancer (NSCLC). This retrospective review included stage I NSCLC patients in whom SBRT was performed at a total dose of 48.0–50.5 Gy in four or five fractions. The tumor volumes observed on computed tomography (CT) simulation and on the CT performed at the last treatment session using a CT-on-rails system were measured and compared. Then, the tumor volume changes during the SBRT period were measured and assessed for their association with prognoses (overall survival, local control, lymph node metastases and distant metastases). A total of 98 patients with a mean age of 78.6 years were enrolled in the study. The T-stage was T1a in 42%, T1b in 32% and T2a in 26% of the cases. The gross tumor volume (GTV) shrank and increased ≥10% in 23 (23.5%) and 36 (36.7%) of the cases, respectively. The 5-year local control and overall survival rates in the groups with a tumor shrinkage of ≥10% vs the group with a shrinkage of <10% were 94.7 vs 70.8% and 85.4 vs 47.6%, respectively; these differences were significant, with a P-value < 0.05. During a short SBRT period, the tumor shrank or enlarged in a small number of cases. A decrease of ≥10% in the GTV during SBRT was significantly related to better overall survival and local control.


Author(s):  
J.L. Fox ◽  
E. Ford ◽  
K. Janson ◽  
J. Zhou ◽  
L. Myers ◽  
...  

2006 ◽  
Vol 33 (6Part5) ◽  
pp. 2034-2034
Author(s):  
E Ford ◽  
D Song ◽  
E Tryggestad ◽  
T McNutt ◽  
J Wong

2016 ◽  
Vol 11 (7) ◽  
pp. 1074-1080 ◽  
Author(s):  
Tomoyoshi Takenaka ◽  
Koji Yamazaki ◽  
Naoko Miura ◽  
Ryo Mori ◽  
Sadanori Takeo

2006 ◽  
Vol 54 (2) ◽  
pp. 112-116 ◽  
Author(s):  
A. Iwasaki ◽  
T. Shirakusa ◽  
S. Enatsu ◽  
S. Maekawa ◽  
T. Hamada ◽  
...  

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