Comparison of unconfined compression and spatially modulated ultrasound radiation force estimates of shear modulus.

2009 ◽  
Vol 125 (4) ◽  
pp. 2552-2552 ◽  
Author(s):  
Stephen A. McAleavey ◽  
Erin Collins ◽  
Etana Elegbe ◽  
Johanna Kelly
2009 ◽  
Vol 31 (4) ◽  
pp. 217-234 ◽  
Author(s):  
Stephen McAleavey ◽  
Manoj Menon ◽  
Etana Elegbe

The application of Spatially-Modulated Ultrasound Radiation Force (SMURF) to shear modulus imaging is demonstrated in tissue-mimicking phantoms and porcine liver. Scanning and data acquisition was performed with a Siemens Antares ultrasound scanner and VF7-3 linear array operating at 4.21 MHz. Modulus estimates in uniform phantoms of Zerdine with shear moduli of 5.1 and 12.4 kPa exhibited standard deviations within 6% of the mean value. Zerdine spheres 1 cm in diameter (nominally 2.7, 4.7 and 15 kPa) in a 8 kPa (nominal) background are clearly resolved. Cross sectional images of a soft conical inclusion in a gelatin-based phantom indicate a spatial resolution of approximately 2.5 mm. Images of the shear modulus of an ex-vivo sample of porcine liver tissue show an average value of 3 kPa. A stiff lesion induced with 0.5 mL of 10% glutaraldehyde is clearly visible as a region of shear modulus in excess of 10 kPa. A modulus gradient associated with the diffusion of the glutaraldehyde is visible. Two pulse sequences were examined, differing only in the timing of the beams used to generate the shear waves. Details of the beam sequences and subsequent signal processing are presented.


2009 ◽  
Vol 56 (11) ◽  
pp. 2380-2387 ◽  
Author(s):  
A. Karpiouk ◽  
S. Aglyamov ◽  
Y. Ilinskii ◽  
E. Zabolotskaya ◽  
S. Emelianov

Author(s):  
Yi Zheng ◽  
Aiping Yao ◽  
Shigao Chen ◽  
Matthew W. Urban ◽  
Randy Kinnick ◽  
...  

New vibration pulses are proposed to increase the power of shear waves induced by ultrasound radiation force in a tissue region with a preferred spectral distribution. The new pulses are sparsely sampled from an orthogonal frequency wave composed of several sinusoidal signals. Those sinusoidal signals have different frequencies and are orthogonal to each other. The phase and amplitude of each sinusoidal signal are adjusted to control the shape of the orthogonal frequency wave. Amplitude of the sinusoidal signal is increased as its frequency increases to compensate for higher loss at higher frequency in the tissue region. The new vibration pulses and detection pulses can be interleaved for array transducer applications. The experimental results show that the new vibration pulses significantly increases induced tissue vibration with the same peak ultrasound intensity, compared with the binary vibration pulses.


2009 ◽  
Vol 125 (3) ◽  
pp. 1410-1415 ◽  
Author(s):  
Yi Hu ◽  
Dong Zhang ◽  
Hairong Zheng ◽  
Xiufen Gong

2005 ◽  
Vol 118 (5) ◽  
pp. 2829-2840 ◽  
Author(s):  
Samuel Callé ◽  
Jean-Pierre Remenieras ◽  
Olivier Bou Matar ◽  
Melouka Elkateb Hachemi ◽  
Frédéric Patat

2007 ◽  
Vol 33 (6) ◽  
pp. 959-969 ◽  
Author(s):  
David Melodelima ◽  
Jeffrey C. Bamber ◽  
Francis A. Duck ◽  
Jacqueline A. Shipley

2006 ◽  
Vol 111 (1-2) ◽  
pp. 128-134 ◽  
Author(s):  
Aaron F.H. Lum ◽  
Mark A. Borden ◽  
Paul A. Dayton ◽  
Dustin E. Kruse ◽  
Scott I. Simon ◽  
...  

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