KINETIC ISOTOPE EFFECTS IMPLICATE A SINGLE OXIDANT FOR CYTOCHROME P450-MEDIATED O-DEALKYLATION, N-OXYGENATION, AND AROMATIC HYDROXYLATION OF 6-METHOXYQUINOLINE

2006 ◽  
Vol 34 (8) ◽  
pp. 1288-1290 ◽  
Author(s):  
Tamara S. Dowers ◽  
Jeffrey P. Jones
Keyword(s):  
Cytochrome P450 ◽  
Isotope Effects ◽  
Kinetic Isotope Effects ◽  
Kinetic Isotope ◽  
Aromatic Hydroxylation

Kinetic Isotope Effects in a C−H Bond Dissociation by the Iron-Oxo Species of Cytochrome P450

2000 ◽  
Vol 104 (51) ◽  
pp. 12365-12370 ◽  
Author(s):  
Kazunari Yoshizawa ◽  
Yoshihisa Kagawa ◽  
Yoshihito Shiota
Keyword(s):  
Cytochrome P450 ◽  
Isotope Effects ◽  
Kinetic Isotope Effects ◽  
Bond Dissociation ◽  
Kinetic Isotope

Kinetic Isotope Effects Implicate Two Electrophilic Oxidants in Cytochrome P450-Catalyzed Hydroxylations

2003 ◽  
Vol 125 (20) ◽  
pp. 6064-6065 ◽  
Author(s):  
Martin Newcomb ◽  
David Aebisher ◽  
Runnan Shen ◽  
R. Esala P. Chandrasena ◽  
Paul F. Hollenberg ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Isotope Effects ◽  
Kinetic Isotope Effects ◽  
Kinetic Isotope
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