Enzymatic Alteration of Nucleic Acid Structure: Enzymes put finishing touches characteristic of each species on RNA and DNA by insertion of methyl groups.

Science ◽  
1964 ◽  
Vol 145 (3632) ◽  
pp. 548-553 ◽  
Author(s):  
P. R. Srinivasan ◽  
E. Borek
Keyword(s):  
Nucleic Acid ◽  
Methyl Groups ◽  
Nucleic Acid Structure ◽  
Acid Structure ◽  
Rna And Dna

scholarly journals Chemical etiology of nucleic acid structure

2000 ◽  
Vol 72 (3) ◽  
pp. 343-345 ◽  
Author(s):  
A. Eschenmoser ◽  
R. Krishnamurthy
Keyword(s):  
Nucleic Acid ◽  
Chemical Properties ◽  
Nucleic Acid Structure ◽  
Acid Structure ◽  
Rna And Dna

The synthesis of potentially natural nucleic acid alternatives and comparison of some of their chemical properties with those of RNA and DNA have led to findings that we consider to be relevant in the context of a chemical etiology of nucleic acid structure.

scholarly journals ASAXS quantifies counterion distributions around DNA and RNA

2014 ◽  
Vol 70 (a1) ◽  
pp. C1579-C1579
Author(s):  
Lois Pollack
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acid Structure ◽  
Ion Distribution ◽  
Dna And Rna ◽  
Charge Interaction ◽  
The Relationship ◽  
Oppositely Charged ◽  
Scattering Signal ◽  
Acid Structure ◽  
Rna And Dna

Because both RNA and DNA carry large negative charge, interaction with oppositely charged partners is required for folding to functional structures. For example, counterions fold RNA and condense DNA. Despite these important roles, ion detection remains elusive. I describe the application of anomalous SAXS methods that highlight the contribution to the scattering signal arising from counterions [1]. In addition to measuring ion distribution, we also count the number of excess ions surrounding a nucleic acid structure [2,3]. Taken together, measurements of ion number and spatial distribution provide an understanding of the relationship between counterions and nucleic acid structure. Present ASAXS work in the Pollack lab is supported by the NIH through grants R01 GM085062 and R01 GM099450.

ChemInform Abstract: Applications of Psoralens as Probes of Nucleic Acid Structure and Function

ChemInform ◽  
2010 ◽  
Vol 22 (16) ◽  
pp. no-no
Author(s):  
Y. B. SHI ◽  
S. E. LIPSON ◽  
D. Y. CHI ◽  
H. P. SPIELMANN ◽  
J. A. MONFORTE ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Structure And Function ◽  
Nucleic Acid Structure ◽  
And Function ◽  
Acid Structure

scholarly journals 2P123 Bacterial ribosomal RNA as a target for sequence-specific inhibition(05A. Nucleic acid: Structure & Property,Poster)

2013 ◽  
Vol 53 (supplement1-2) ◽  
pp. S179
Author(s):  
Joanna Tyylska ◽  
Sapna G. Thoduka ◽  
Zofia Dabrowska ◽  
Anna Gorska ◽  
Maciej Jasinski ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Ribosomal Rna ◽  
Specific Inhibition ◽  
Structure Property ◽  
Nucleic Acid Structure ◽  
Acid Structure
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