Developmental Abnormalities: Teratology of the Central Nervous System . Induced and Spontaneous Malformations of Laboratory, Agricultural, and Domestic Mammals. Harold Kalter. University of Chicago Press, Chicago, 1968. xvi + 481 pp., illus. $17.50.

Science ◽  
1968 ◽  
Vol 162 (3859) ◽  
pp. 1259-1259
Author(s):  
Samuel P. Hicks
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
University Of Chicago ◽  
Developmental Abnormalities ◽  
The Central Nervous System ◽  
University Of Chicago Press

Teratology of the Central Nervous System, by Harold Kalter. Chicago: The University of Chicago Press, 1968, 483 pp., $17.50

PEDIATRICS ◽  
1969 ◽  
Vol 44 (4) ◽  
pp. 626-627
Author(s):  
Floyd H. Gilles
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Congenital Malformations ◽  
University Of Chicago ◽  
Valuable Source ◽  
The Central Nervous System ◽  
Animal Part ◽  
The University ◽  
University Of Chicago Press

Kalter monograph is a compendium of congenital malformations of the central nervous system organized by agent or method (Part 1) or by animal (Part 2). As such, it is a valuable source of teratological information up to the year 1967. While largely a résumé of literature, it includes a reserved presentation of the author contribution to teratology.

TERATOLOGY OF THE CENTRAL NERVOUS SYSTEM, by Harold Kalter. Chicago: The University of Chicago Press, 1968, 483 pp., $17.50

PEDIATRICS ◽  
1970 ◽  
Vol 46 (5) ◽  
pp. 827-828
Author(s):  
Floyd H. Gilles
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Congenital Malformations ◽  
University Of Chicago ◽  
Valuable Source ◽  
The Central Nervous System ◽  
Animal Part ◽  
The University ◽  
University Of Chicago Press

Kalter's monograph is a compendium of congenital malformations of the central nervous system organized by agent or method (Part 1) or by animal (Part 2). As such it is a valuable source of teratological information to 1967. While largely a resume of literature, it includes a reserved presentation of the author's contribution to teratology. The bibliography of 94 pages seems well coordinated not only by the organization of individual chapters but by adequate author and subject indices.

Developmental abnormalities of the central nervous system

2020 ◽  
pp. 6350-6367
Author(s):  
Christopher M. Verity ◽  
Jane A. Hurst ◽  
Helen V. Firth
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
System Development ◽  
Complex Structure ◽  
Nervous System Development ◽  
Developmental Abnormalities ◽  
System P ◽  
The Family ◽  
The Central Nervous System ◽  
Brain And Spinal Cord

This chapter deals with abnormalities that may result from failures at particular stages of central nervous system development. The brain and spinal cord arise from a sheet of cells that undergo transformations into the final complex structure. Failure of closure of the neural tube may result in anencephaly or spina bifida and failure of regionalization may cause holoprosencephaly. Disorders of neural proliferation or migration cause abnormalities of the cerebral cortex. There are distinct malformations of the posterior fossa structures and there are complex malformations that cannot be ascribed to just one abnormal step in development. The clinical problems associated with developmental abnormalities of the central nervous system are discussed and the approach to obtaining a clinical molecular diagnosis and providing genetic advice to the family is outlined.

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