Noninvasive study of high-energy phosphate metabolism in human heart by depth-resolved 31P NMR spectroscopy

Science ◽  
1985 ◽  
Vol 229 (4715) ◽  
pp. 769-772 ◽  
Author(s):  
P. Bottomley
Keyword(s):  
Nmr Spectroscopy ◽  
Human Heart ◽  
31P Nmr ◽  
High Energy ◽  
31P Nmr Spectroscopy ◽  
Phosphate Metabolism ◽  
High Energy Phosphate ◽  
High Energy Phosphate Metabolism

Effects of Halothane on Myocardial High-energy Phosphate Metabolism and Intracellular  p H Utilizing 31P NMR Spectroscopy 

1987 ◽  
Vol 67 (5) ◽  
pp. 649-653 ◽  
Author(s):  
Paul A. Murray ◽  
Thomas J. J. Blanck ◽  
Mark C. Rogers ◽  
William E. Jacobus
Keyword(s):  
Nmr Spectroscopy ◽  
31P Nmr ◽  
High Energy ◽  
31P Nmr Spectroscopy ◽  
Phosphate Metabolism ◽  
High Energy Phosphate ◽  
High Energy Phosphate Metabolism

Skeletal muscle bioenergetics during frequency-dependent fatigue

1991 ◽  
Vol 260 (3) ◽  
pp. C643-C651 ◽  
Author(s):  
C. R. Bridges ◽  
B. J. Clark ◽  
R. L. Hammond ◽  
L. W. Stephenson
Keyword(s):  
Skeletal Muscle ◽  
Nmr Spectroscopy ◽  
31P Nmr ◽  
High Energy ◽  
Metabolic Energy ◽  
31P Nmr Spectroscopy ◽  
External Work ◽  
Dynamic Contractions ◽  
High Energy Phosphate Metabolism

The bioenergetic correlates of skeletal muscle fatigue were assessed in vivo with phosphorus-31 nuclear magnetic resonance (31P-NMR) spectroscopy. After surgical construction of latissimus dorsi muscle ventricles, seven beagles underwent 31P-NMR spectroscopy during 12-min exercise protocols at 25- and 85-Hz stimulation frequencies and during both isovolumetric and dynamic contractions. Exercise at 85 Hz was associated with significantly greater fatigue than exercise at 25 Hz. At both frequencies, the onset of exercise was associated with a marked increase in inorganic phosphate (Pi) and a decrease in phosphocreatine (PCr). As the muscle fatigued at 85 Hz but not at 25 Hz, the phosphorus spectra returned to near baseline with a decrease in Pi and increase in PCr. For a given amount of force generated, the Pi-to-PCr ratio was higher for dynamic contractions than for isovolumetric contractions. This study indicates that high-frequency fatigue is unlikely to result from the direct effects of high-energy phosphate metabolism and that contractions producing external work consume more metabolic energy than equally forceful isometric contractions.

Determination of high-energy phosphate compounds in fish muscle: 31P-NMR spectroscopy and enzymatic methods

1990 ◽  
Vol 95 (4) ◽  
pp. 789-795 ◽  
Author(s):  
Guido van den Thillart ◽  
Aren van Waarde ◽  
Henk Jan Muller ◽  
Cees Erkelens ◽  
Johan Lugtenburg
Keyword(s):  
Nmr Spectroscopy ◽  
31P Nmr ◽  
Fish Muscle ◽  
High Energy ◽  
31P Nmr Spectroscopy ◽  
High Energy Phosphate ◽  
Enzymatic Methods ◽  
Phosphate Compounds

High‐Energy Phosphate Metabolism during Exercise and Recovery in Temperate and Antarctic Scallops: An In Vivo 31P‐NMR Study

2003 ◽  
Vol 76 (5) ◽  
pp. 622-633 ◽  
Author(s):  
David M. Bailey ◽  
Lloyd S. Peck ◽  
Christian Bock ◽  
Hans‐Otto Pörtner
Keyword(s):  
31P Nmr ◽  
High Energy ◽  
Phosphate Metabolism ◽  
High Energy Phosphate ◽  
Nmr Study ◽  
High Energy Phosphate Metabolism

Interleaved MRI/MRS study of muscle perfusion, oxygenation and high energy phosphate metabolism in normal subjects and Becker's myopathic patients

1998 ◽  
Vol 95 (2) ◽  
pp. 250-255
Author(s):  
J. F. Toussaint ◽  
C. Brillault-Salvat ◽  
E. Giacomini ◽  
G. Bloch ◽  
D. Duboc ◽  
...  
Keyword(s):  
Normal Subjects ◽  
High Energy ◽  
Phosphate Metabolism ◽  
High Energy Phosphate ◽  
Muscle Perfusion ◽  
High Energy Phosphate Metabolism
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