Natural antibodies to human retrovirus HTLV in a cluster of Japanese patients with adult T cell leukemia

Science ◽  
1982 ◽  
Vol 215 (4535) ◽  
pp. 975-978 ◽  
Author(s):  
M Robert-Guroff ◽  
Y Nakao ◽  
K Notake ◽  
Y Ito ◽  
A Sliski ◽  
...  
Keyword(s):  
T Cell ◽  
Japanese Patients ◽  
Natural Antibodies ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia ◽  
Human Retrovirus

Experimental infection of cynomolgus monkeys with a human retrovirus, adult T-cell leukemia virus

1984 ◽  
Vol 173 (1) ◽  
pp. 57-64 ◽  
Author(s):  
N. Yamamoto ◽  
M. Hayami ◽  
A. Komuro ◽  
J. Schneider ◽  
G. Hunsmann ◽  
...  
Keyword(s):  
T Cell ◽  
Experimental Infection ◽  
Leukemia Virus ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Cynomolgus Monkeys ◽  
Adult T Cell Leukemia ◽  
T Cell Leukemia Virus ◽  
Human Retrovirus

Human retrovirus in adult T-cell leukemia/lymphoma

1985 ◽  
Vol 6 (3) ◽  
pp. 83-88 ◽  
Author(s):  
Kazuo Sugamura ◽  
Yorio Hinuma
Keyword(s):  
T Cell ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia ◽  
Human Retrovirus

Abnormalities of chromosome 14 at band 14q11 in Japanese patients with adult T-cell leukemia

1985 ◽  
Vol 17 (3) ◽  
pp. 279-282 ◽  
Author(s):  
Naoki Sadamori ◽  
Miyuki Kusano ◽  
Kenji Nishino ◽  
Masuko Tagawa ◽  
Ei-ichi Yao ◽  
...  
Keyword(s):  
T Cell ◽  
Japanese Patients ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Chromosome 14 ◽  
Adult T Cell Leukemia

scholarly journals Significance of chromosome 14 anomaly at band 14Q11 in Japanese patients with adult T-cell leukemia

Cancer ◽  
1986 ◽  
Vol 58 (10) ◽  
pp. 2244-2250 ◽  
Author(s):  
Naoki Sadamori ◽  
Kenji Nishino ◽  
Miyuki Kusano ◽  
Yu Tomonaga ◽  
Masuko Tagawa ◽  
...  
Keyword(s):  
T Cell ◽  
Japanese Patients ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Chromosome 14 ◽  
Adult T Cell Leukemia

Interferon-α and zidovudine for relapsed/refractory adult T cell leukemia/lymphoma: case reports of Japanese patients

2010 ◽  
Vol 92 (5) ◽  
pp. 762-764 ◽  
Author(s):  
Kenji Ishitsuka ◽  
Hiroo Katsuya ◽  
Tomona Toyota ◽  
Masanao Ishizu ◽  
Naoko Kunami ◽  
...  
Keyword(s):  
T Cell ◽  
Case Reports ◽  
Japanese Patients ◽  
Interferon Α ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia

scholarly journals Chromosome studies in adult T-cell leukemia in Japan: significance of trisomy 7

Blood ◽  
1981 ◽  
Vol 58 (3) ◽  
pp. 420-425 ◽  
Author(s):  
Y Ueshima ◽  
S Fukuhara ◽  
T Hattori ◽  
T Uchiyama ◽  
K Takatsuki ◽  
...  
Keyword(s):  
T Cell ◽  
Peripheral Blood ◽  
Sex Chromosome ◽  
Marker Chromosome ◽  
Japanese Patients ◽  
Chromosome Abnormalities ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia ◽  
Abnormal Cells

Abstract Chromosomes were studied in cells from 15 japanese patients with adult T-cell leukemia (ATL). Mitoses were obtained from unstimulated peripheral blood in 12 patients and a lymph node in one patient. In two other patients, mitotic cells were obtained solely from peripheral blood stimulated with phytohemagglutinin (PHA). Chromsomally abnormal cells were seen in 14 of the 15 patients. The abnormal cells had a modal number of chromosomes in near diploid range in 12 patients, and in near triploid and tetraploid range in the remaining 2 patients, respectively. Eight of the nine patients analyzed by Q-banding had clonal chromosome abnormalities. The most common abnormality was trisomy no.7 or 7q, which was seen in 5 cases and has been primarily observed in lymphoid neoplasms. A 14q+ marker chromosome was found in two patients and a Dq+ in one patient; loss of a sex chromosome was found in three patients. Most chromosomes were involved in gains, losses, or structural rearrangements, but abnormalities of no. 11, which have been frequently found in lymphoid malignancies, was not observed in our series. The significance of these chromosome abnormalities is discussed.

Major prognostic factors of Japanese patients with lymphoma-type adult T-cell leukemia

1990 ◽  
Vol 35 (4) ◽  
pp. 232-237 ◽  
Author(s):  
Yoshinori Shimamoto ◽  
Kenji Suga ◽  
Junji Nishimura ◽  
Hajime Nawata ◽  
Masaya Yamaguchi
Keyword(s):  
Prognostic Factors ◽  
T Cell ◽  
Japanese Patients ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia ◽  
Lymphoma Type
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