Fourteen-Member Macrolides Suppress Interleukin-8 Production but Do Not Promote Apoptosis of Activated Neutrophils
2002 ◽
Vol 46
(4)
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pp. 1101-1104
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Keyword(s):
ABSTRACT A 14-member macrolide was found to inhibit interleukin-8 (IL-8) synthesis in lipopolysaccharide-stimulated neutrophils but did not accelerate apoptosis in activated neutrophils. These data suggest that 14-member macrolides achieve clinical efficacy for chronic airway diseases partly by suppressing IL-8 production by activated neutrophils, but not by enhancing apoptosis in these cells.
1994 ◽
Vol 62
(10)
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pp. 4145-4152
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2017 ◽
Vol 12
(5)
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pp. 1830-1837
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Keyword(s):
2020 ◽
Vol 879
◽
pp. 173139
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2008 ◽
Vol 118
(1)
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pp. 128-137
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2011 ◽
Vol 301
(1)
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pp. L31-L39
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Keyword(s):