scholarly journals Large-scale production of mouse mammary tumor virus in the absence of endogenous murine leukemia virus.

1979 ◽  
Vol 37 (1) ◽  
pp. 148-158 ◽  
Author(s):  
C V Benton ◽  
J S Harshman ◽  
O R Robinson ◽  
G P Shibley
Keyword(s):  
Murine Leukemia Virus ◽  
Mouse Mammary Tumor Virus ◽  
Large Scale ◽  
Leukemia Virus ◽  
Scale Production ◽  
Mammary Tumor Virus ◽  
Large Scale Production ◽  
Mouse Mammary Tumor ◽  
Tumor Virus ◽  
Murine Leukemia

scholarly journals Construction and Characterization of a Hybrid Mouse Mammary Tumor Virus/Murine Leukemia Virus-Based Retroviral Vector

1998 ◽  
Vol 72 (2) ◽  
pp. 1699-1703 ◽  
Author(s):  
Robert M. Saller ◽  
Feride Öztürk ◽  
Brian Salmons ◽  
Walter H. Günzburg
Keyword(s):  
Mammary Tumor ◽  
Murine Leukemia Virus ◽  
Mouse Mammary Tumor Virus ◽  
Leukemia Virus ◽  
Regulation Of Gene Expression ◽  
Mammary Tumor Virus ◽  
Mouse Mammary Tumor ◽  
Tumor Virus ◽  
Specific Regulation ◽  
Murine Leukemia

ABSTRACT Mouse mammary tumor virus (MMTV)-based vectors are characterized by low titers. In an effort to transfer MMTV-specific regulation of gene expression to a more efficient murine leukemia virus (MLV) vector, we have replaced the complete 3′ U3 region of MLV with the complete U3 region of MMTV. Virus titers were not significantly affected by this modification, there was no impairment of reverse transcription and integration, and after infection of cells, the MMTV promoter is duplicated and translocated to the 5′ long terminal repeat, resulting in glucocorticoid-regulatable RNA expression.

Studies of Mouse Mammary Tumor Virus by Ferritin-labeled Antibody

1970 ◽  
Vol 28 ◽  
pp. 170-171
Author(s):  
T. Kodama ◽  
W. C. Williams ◽  
R. L. Hales ◽  
L. Dmochowski
Keyword(s):  
Virus Type ◽  
Mammary Tumor ◽  
Mouse Mammary Tumor Virus ◽  
Leukemia Virus ◽  
Mammary Tumors ◽  
Mammary Tumor Virus ◽  
Mouse Mammary Tumor ◽  
Mouse Mammary Tumors ◽  
Mouse Leukemia Virus ◽  
Tumor Virus

Morphological, biological, and immunological studies indicate a possible interrelationship between mouse mammary tumor virus and leukemia virus in the development of mouse mammary tumors. Electron microscope studies have shown the presence of both mouse mammary tumor virus (type B) particles and mouse leukemia virus (type C) particles in mouse milk, in tissues, and in tissue cultures from spontaneous and induced mouse mammary tumors (Dmochowski, L., et; al.: Carcinogenesis, A Broad Critique, Williams and Wilkins Co., Baltimore, p.211, 1967;., Dmochowski, L., et al.: J.Nat. Cancer Inst., 40:1339, 1968).

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