scholarly journals Restricted Isotypic Antibody Reactivity to Hepatitis C Virus Synthetic Peptides in Immunocompromised Patients

1999 ◽  
Vol 6 (2) ◽  
pp. 279-281 ◽  
Author(s):  
Marisol Devesa ◽  
Arlette de Saez ◽  
Graciela León ◽  
Firelei Sirit ◽  
Clarisa Cosson ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Enzyme Immunoassay ◽  
Synthetic Peptides ◽  
Immunocompromised Patients ◽  
The Core ◽  
Antibody Reactivity ◽  
Antibody Isotypes ◽  
Immune Impairment ◽  
Core Peptide

ABSTRACT An enzyme immunoassay based on three synthetic peptides from the core, NS4, and NS5 regions of hepatitis C virus allowed the detection of antibodies in 100% of immunocompetent infected patients and in 91% of immunocompromised patients (hemodialysis and hemophiliac patients). Immune impairment seemed to restrict the spectrum of antibody isotypes reacting to the core peptide.

Characterization of the Antibody Reactivity to Synthetic Peptides from Different Parts of the Hepatitis C Virus Genome

1996 ◽  
Vol 9 (2) ◽  
pp. 89-96 ◽  
Author(s):  
FLOR H. PUJOL ◽  
YURY E. KHUDYAKOV ◽  
MARISOL DEVESA ◽  
GRACIELA LEÓN ◽  
LINDA BLITZ-DORFMAN ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Synthetic Peptides ◽  
Virus Genome ◽  
Antibody Reactivity ◽  
Different Parts

scholarly journals Comparison of DNA Enzyme Immunoassay and Line Probe Assays (Inno-LiPA HCV I and II) for Hepatitis C Virus Genotyping

1998 ◽  
Vol 36 (5) ◽  
pp. 1461-1463 ◽  
Author(s):  
S. Le Pogam ◽  
F. Dubois ◽  
R. Christen ◽  
C. Raby ◽  
A. Cavicchini ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Enzyme Immunoassay ◽  
Untranslated Regions ◽  
Line Probe Assay ◽  
The Core ◽  
Probe Assay ◽  
Dna Enzyme Immunoassay

Two methods for genotyping hepatitis C virus (DNA enzyme immunoassay [DEIA] and line probe assay [Inno-LiPA HCV I and II]) were compared on 120 samples and of these 87% were assigned to the same subtype by both assays. There were 15 subtyping discrepancies which involved 5% of type 1 isolates and 90% of type 2 isolates. Amplified products from the core and 5′ untranslated regions (UTR) were sequenced to resolve conflicts. Type 1 discordant samples had a guanosine at position −99 in the 5′ UTR, a characteristic of genotype 1b, and a core region typical of subtype 1a. The eight isolates classified as 2a/2c by LiPA and as subtype 2c by DEIA belonged to type 2.

Variation in Antibody Reactivity to the Hepatitis C Virus by Comparative Immunoscreening and Enzyme Immunoassay

1993 ◽  
Vol 6 (1) ◽  
pp. 49-54
Author(s):  
ROBERT G. GISH ◽  
MARIA T. WARMERDAM ◽  
JEROME B. ZELDIS ◽  
EMMET B. KEEFFE ◽  
PAUL NAKAZATO ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Enzyme Immunoassay ◽  
Antibody Reactivity

Prevalence of hepatitis C virus (HCV) antibodies as assessed by a second generation enzyme immunoassay in patients on chronic hemodialysis

1991 ◽  
Vol 13 ◽  
pp. S35
Author(s):  
A. Hatzidaki ◽  
A. Katsoulidou ◽  
V. Miriagou ◽  
L. Pani ◽  
S. Voudiklari ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Enzyme Immunoassay ◽  
Second Generation ◽  
Chronic Hemodialysis

Prevalence of infection with hepatitis C virus in Venezuela, as assessed with an immuno-assay based on synthetic peptides

2001 ◽  
Vol 95 (2) ◽  
pp. 187-195 ◽  
Author(s):  
M. S. Aguilar ◽  
C. Cosson ◽  
C. L. Loureiro ◽  
M. Devesa ◽  
J. Martínez ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Synthetic Peptides ◽  
Immuno Assay
Sign in / Sign up

Export Citation Format

Share Document