scholarly journals Single Nucleotide Polymorphism in the Cytolethal Distending Toxin B Gene Confers Heterogeneity in the Cytotoxicity of Actinobacillus actinomycetemcomitans

2006 ◽  
Vol 74 (12) ◽  
pp. 7014-7020 ◽  
Author(s):  
Shuichi Nishikubo ◽  
Masaru Ohara ◽  
Masae Ikura ◽  
Katsuo Katayanagi ◽  
Tamaki Fujiwara ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Amino Acid ◽  
Actinobacillus Actinomycetemcomitans ◽  
Single Amino Acid ◽  
Polymorphism Analysis ◽  
Cytolethal Distending Toxin ◽  
Single Nucleotide Polymorphism Analysis ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Toxin B

ABSTRACT Clinical Actinobacillus actinomycetemcomitans produces cytolethal distending toxin (CDT) with titers ranging from 102 to 108 U/mg. Single nucleotide polymorphism analysis of the cdt gene in clinical isolates identified a variation of a single amino acid at residue 281 of CdtB, which significantly affected CDT toxicity by modulating the chromatin-degrading activity of CdtB.

scholarly journals Flow Cytometric Platform for High-Throughput Single Nucleotide Polymorphism Analysis

BioTechniques ◽  
2001 ◽  
Vol 30 (3) ◽  
pp. 661-669 ◽  
Author(s):  
J.D. Taylor ◽  
D. Briley ◽  
Q. Nguyen ◽  
K. Long ◽  
M.A. Iannone ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
High Throughput ◽  
Polymorphism Analysis ◽  
Single Nucleotide Polymorphism Analysis ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Flow Cytometric

Single-Nucleotide Polymorphism Analysis by Pyrosequencing

2000 ◽  
Vol 280 (1) ◽  
pp. 103-110 ◽  
Author(s):  
Afshin Ahmadian ◽  
Baback Gharizadeh ◽  
Anna C. Gustafsson ◽  
Fredrik Sterky ◽  
Pål Nyrén ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Polymorphism Analysis ◽  
Single Nucleotide Polymorphism Analysis ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide
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