A Single-Copy Gene Encodes Kex1, a Serine Endoprotease of Pneumocystis jiroveci
2003 ◽
Vol 71
(1)
◽
pp. 571-574
◽
Keyword(s):
ABSTRACT We have cloned and characterized the kex1 gene of Pneumocystis jiroveci. Unlike the case for Pneumocystis carinii, in which the homologous PRT-1 genes are multicopy, kex1 is a single-copy gene encoding a protein homologous to fungal serine endoproteases, which localize to the Golgi apparatus. Thus, substantial biological differences can be seen among Pneumocystis species.