scholarly journals Nucleic acid renaturation and restriction endonuclease cleavage analyses show that the DNAs of a transforming and a nontransforming strain of Epstein-Barr virus share approximately 90% of their nucleotide sequences.

1976 ◽  
Vol 18 (2) ◽  
pp. 765-775 ◽  
Author(s):  
B Sugden ◽  
W C Summers ◽  
G Klein
Keyword(s):  
Nucleic Acid ◽  
Restriction Endonuclease ◽  
Epstein Barr Virus ◽  
Nucleotide Sequences ◽  
Barr Virus ◽  
Epstein Barr ◽  
Restriction Endonuclease Cleavage

scholarly journals Hydroa Vacciniforme-like Lymphoproliferative disorder in an adult invades the liver and bone marrow with clear pathological evidence: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiankun Wang ◽  
Peng Wang ◽  
Aibin Wang ◽  
Yanli Xu ◽  
Lin Wang ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Nucleic Acid ◽  
Lymphoproliferative Disorder ◽  
Epstein Barr Virus ◽  
Antiviral Treatment ◽  
Barr Virus ◽  
Eb Virus ◽  
Hydroa Vacciniforme ◽  
Epstein Barr ◽  
Acid Test

Abstract Background Hydroa Vacciniforme-like Lymphoproliferative Disorder (HV-LPD) is the name given to a group of Epstein-Barr virus (EBV)-associated diseases. It resembles hydroa vacciniforme (HV), the rarest form of photosensitivity, and is a T-cell disorder associated with an Epstein-Barr virus infection. The majority of diagnosed cases occur in East Asia and South America. It is rare in the United States and Europe. Multiple studies have revealed the clinical manifestation of an enlarged liver, but no gold standard such as pathology has yet supported this as a clinical sign of HV-LPD. Case presentation Here, we report a case of a 34-year-old Asian female with definite liver invasion. The patient had complained of a recurring facial rash for many years. The patient was admitted to the hospital because of an enlarged liver. After hospitalization, she was given an EB virus nucleic acid test. The EB virus nucleic acid test was positive, and pathological examination suggested that HV-LPD had invaded the skin, bone marrow, and liver. After being given antiviral treatment, the patient’s symptoms were mitigated. Conclusions Our case confirms the liver damage was caused by HV-LPD and the effectiveness of antiviral treatment.

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